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Long-Acting Muscarinic Antagonists

Long-acting muscarinic antagonists are used to help manage the symptoms of COPD. These medications work by continually relaxing the lungs and maintaining an open airway to improve symptoms such as shortness of breath.

Why are long acting muscarinic antagonists prescribed?

  1. COPD (90%)
  2. Asthma (10%)

Key takeaways

Long-acting muscarinic antagonists (LAMAs) are primarily used to treat chronic obstructive pulmonary disease (COPD). But certain medications in this class can also be used for asthma. LAMAs work by blocking the action of acetylcholine, a chemical that causes the muscles around your airways to tighten, making it easier for you to breathe. These medications come in different forms, including inhalers and nebulizer solutions. Examples include tiotropium (Spiriva Handihaler, Spiriva Respimat), umeclidinium (Incruse Ellipta), and aclidinium (Tudorza Pressair). You can discuss with your healthcare team which option might be right for you.

Prices for popular Long-Acting Muscarinic Antagonists medications
Viewing 5 of 5 medications
handihaler icon

Spiriva Handihaler (tiotropium)

as low as$72
TIOTROPIUM treats chronic obstructive pulmonary disease (COPD). It works by opening the airways of the lungs, making it easier to breathe. It is often called a controller inhaler. Do not use it to treat a sudden COPD flare-up.
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inhaler icon

Incruse Ellipta

as low as$345
Incruse Ellipta (umeclidinium) is used for COPD, including chronic bronchitis and emphysema. Incruse Ellipta is slightly less popular than other anticholinergics. There are currently no generic alternatives for Incrue Ellipta.

Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Incruse Ellipta is covered by most Medicare and insurance plans.
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inhaler icon

Tudorza Pressair

as low as$345
Tudorza Pressair (aclidinium) is used to treat chronic obstructive pulmonary disease (COPD), including emphysema and chronic bronchitis. Tudorza Pressair is less popular than other anticholinergics. There are currently no generic alternatives to Tudorza Pressair.

Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Tudorza Pressair is covered by some Medicare and insurance plans.
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respimat-inhaler icon

Spiriva Respimat

as low as$511
TIOTROPIUM treats asthma and chronic obstructive pulmonary disease (COPD). It works by opening the airways of the lungs, making it easier to breathe. It is often called a controller inhaler. Do not use it to treat a sudden asthma attack or COPD flare-up.
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carton icon

Yupelri

as low as$1,317
REVEFENACIN treats chronic obstructive pulmonary disease (COPD). It works by opening the airways of the lungs, making it easier to breathe. It is often called a controller medication. Do not use it to treat a sudden COPD flare-up.
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Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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