Key takeaways
Xopenex (levalbuterol) and Breo Ellipta (fluticasone/vilanterol) are both inhaled medications used to help with breathing problems, but they work differently and are used for different purposes. Xopenex is a short-acting beta agonist (SABA) that quickly opens up your airways to relieve sudden wheezing or shortness of breath, and it's typically used three times a day. In contrast, Breo Ellipta is a combination of an inhaled corticosteroid (ICS) and a long-acting beta agonist (LABA) used for the long-term control of asthma and chronic obstructive pulmonary disease (COPD), and it's taken once daily. Xopenex is suitable for children as young as 6 years old, while Breo Ellipta can be used by children as young as 5 years old for asthma. Xopenex requires a nebulizer machine for administration, which can be less convenient, especially when traveling. Breo Ellipta, on the other hand, is a dry powder inhaler that is easier to use and doesn't require a nebulizer. You will need to rinse your mouth out with water after taking your Breo Ellipta dose to prevent oral thrush, a fungal infection in the mouth. Breo Ellipta contains lactose, so it can't be used if you're severely allergic to milk proteins. Both medications have generic versions available, making them more affordable.
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