Head-to-head comparisons of medication uses, side effects, warnings, and more.
Xopenex (levalbuterol) and Breo Ellipta (fluticasone/vilanterol) are both inhaled medications used to help with breathing problems, but they work differently and are used for different purposes. Xopenex is a short-acting beta agonist (SABA) that quickly opens up your airways to relieve sudden wheezing or shortness of breath, and it's typically used three times a day. In contrast, Breo Ellipta is a combination of an inhaled corticosteroid (ICS) and a long-acting beta agonist (LABA) used for the long-term control of asthma and chronic obstructive pulmonary disease (COPD), and it's taken once daily. Xopenex is suitable for children as young as 6 years old, while Breo Ellipta can be used by children as young as 5 years old for asthma. Xopenex requires a nebulizer machine for administration, which can be less convenient, especially when traveling. Breo Ellipta, on the other hand, is a dry powder inhaler that is easier to use and doesn't require a nebulizer. You will need to rinse your mouth out with water after taking your Breo Ellipta dose to prevent oral thrush, a fungal infection in the mouth. Breo Ellipta contains lactose, so it can't be used if you're severely allergic to milk proteins. Both medications have generic versions available, making them more affordable.
Levalbuterol inhalation solution (also known by its brand name, Xopenex) is a short-acting beta agonist (SABA). It's used to treat and prevent sudden wheezing or shortness of breath in people with certain breathing problems, such as asthma. This medication is for adults and children ages 6 years and older. Levalbuterol (Xopenex) inhalation solution is inhaled through the mouth with a nebulizer machine. Side effects of this medication include headache, sore throat, and runny nose. It's available as a lower-cost generic.
Breo is a combination inhaler used for maintenance treatment of chronic obstructive pulmonary disease (COPD) and asthma in adults and children. It contains two active ingredients, fluticasone (an inhaled corticosteroid, or ICS) and vilanterol (a long-acting beta agonist, or LABA). Breo Ellipta (fluticasone / vilanterol) is inhaled through the mouth once per day. It's available as a lower-cost generic. Side effects can differ based on your age and your Breo Ellipta (fluticasone / vilanterol) dose, but generally include upper respiratory tract infections, sore throat, and headache.
Ages 12 years and older:
Ages 6 to 11 years:
COPD:
Asthma (adults):
Asthma (children):
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