Key takeaways
Breo Ellipta (fluticasone furoate / vilanterol) and Trelegy Ellipta (fluticasone / umeclidinium/ vilanterol) are both inhalers used to manage asthma and chronic obstructive pulmonary disease (COPD). They share the active ingredients fluticasone, a corticosteroid, and vilanterol, a long-acting beta agonist (LABA), which help reduce inflammation and relax airway muscles. However, Trelegy Ellipta also includes umeclidinium, a long-acting muscarinic antagonist (LAMA), which further helps to keep airways open. Breo Ellipta is available in generic form, while Trelegy Ellipta does not have a generic version. Both medications are taken once daily, but Breo Ellipta is available in three different strengths, whereas Trelegy Ellipta comes in two strengths for asthma treatment. Common side effects for both include headache and oral thrush, but Trelegy Ellipta may also cause back pain and changes in taste. Additionally, Trelegy Ellipta has more potential drug interactions, such as with beta blockers and tricyclic antidepressants.
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