Key takeaways:
Trelegy Ellipta (fluticasone furoate / umeclidinium / vilanterol) is an inhaler used for asthma and chronic obstructive pulmonary disease (COPD).
The typical Trelegy Ellipta dosage is 1 puff once daily. Your specific dose will depend on whether you have asthma or COPD. If you have asthma, your prescriber may adjust your dose based on your symptoms.
There are ways to save on Trelegy Ellipta, which is available as a brand-name medication. If you’re eligible, you could pay as little as $0 with a manufacturer copay card.
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If you’re living with asthma or chronic obstructive pulmonary disease (COPD), you likely use an inhaler to help manage your symptoms. Maintenance inhalers are key to managing chronic lung conditions. These daily medications help prevent symptoms and flare-ups.
Trelegy Ellipta (fluticasone furoate / umeclidinium / vilanterol) is an example of a maintenance inhaler. It’s FDA approved for both asthma and COPD. It contains three medications that work in different ways to help keep airways open, making it easier to breathe.
If you’re just getting started with Trelegy Ellipta, it’s common to want to know more about it. Knowing how to use it is often top of mind. Below, we review typical Trelegy Ellipta dosages for asthma and COPD. But always follow your prescriber’s directions, even if they’re different from what’s discussed here.
Good to know: Trelegy Ellipta is only approved for use in adults ages 18 and older. So we won’t discuss dosages for children in this article.
What’s the typical Trelegy Ellipta dosage for adults?
The typical Trelegy Ellipta dosage is to inhale 1 dose once daily. But your specific dose depends on why you’re using it and your response.
Trelegy Ellipta comes in the following doses:
100 mcg fluticasone furoate / 62.5 mcg umeclidinium / 25 mcg vilanterol (100/62.5/25 mcg)
200 mcg fluticasone furoate / 62.5 mcg umeclidinium / 25 mcg vilanterol (200/62.5/25 mcg)
Regardless of your dose, be sure to rinse your mouth after using Trelegy Ellipta. This inhaler contains fluticasone furoate, an inhaled corticosteroid (steroid). Steroid inhalers raise the risk of developing oral thrush (a fungal infection of the mouth and throat). Rinsing your mouth with water after using Trelegy Ellipta lowers the risk of this side effect.
Trelegy Ellipta dosage for asthma
Trelegy Ellipta dosages for asthma depend on how severe your asthma is:
For mild-to-moderate asthma: The typical dosage is 1 puff of the 100/62.5/25 mcg dose once daily. If needed, your prescriber can raise your dosage to 1 puff of the 200/62.5/25 mcg dose once daily.
For more severe asthma: The typical dosage is 1 puff of the 200/62.5/25 mcg dose once daily. This is also the maximum Trelegy Ellipta dosage.
Trelegy Ellipta dosage for COPD
The recommended Trelegy Ellipta dosage for COPD is 1 puff of the 100/62.5/25 mcg dose once daily. This is the FDA-approved dosage for this condition. The higher dose wasn’t studied for safety or effectiveness in people with COPD. If Trelegy Ellipta 100/62.5/25 mcg doesn’t work well enough for you, it’s recommended to try a different COPD inhaler.
Are there any dosage adjustments for health conditions?
Many medications have different dosages for people with liver or kidney disease. But this isn’t the case for Trelegy Ellipta. Your dosage depends on what lung condition you have. And if you have asthma, your dosage may be adjusted based on your symptoms.
What happens if you miss a dose of Trelegy Ellipta?
If you forget a dose of Trelegy Ellipta, take your dose as soon as you remember. But if it’s close to time for your next dose, skip the missed one. Then, take your next dose at its usual time. Don’t use Trelegy Ellipta more than once every 24 hours. This can raise your risk of side effects.
Trelegy Ellipta contains multiple medications: Trelegy Ellipta is a long-acting maintenance asthma inhaler that contains several medications to help people get a handle on their symptoms.
A guide to using Trelegy Ellipta: Learn how to use this inhaler for asthma or chronic obstructive pulmonary disease (COPD).
Comparing the costs of asthma inhalers: See how Trelegy Ellipta measures up to other inhalers and find out ways to save on your prescriptions.
What should you do if you use too much Trelegy Ellipta?
Using too much Trelegy Ellipta, or using it too often, can raise your risk of side effects. Relatively common side effects include headache, back pain, and sore throat. But each medication included in Trelegy Ellipta has its own risks when used too much.
The table below lists possible side effects that can happen with each active ingredient in Trelegy Ellipta. These side effects can happen even when you’re using your inhaler as directed. But they become more likely if you use your inhaler more than recommended.
| Fluticasone furoate side effects | Umeclidinium side effects | Vilanterol side effects |
|---|---|---|
|
|
|
These aren’t the only possible side effects. Using Trelegy Ellipta as instructed helps prevent more serious issues.
If you use more Trelegy Ellipta than prescribed, contact your healthcare team. They may ask you to watch for side effects. Or they may want to see you in person. You can also contact Poison Control online or at 1-800-222-1222 for guidance. But if you’re having any severe side effects, seek emergency help.
How to save on Trelegy Ellipta
There are ways to save on Trelegy Ellipta, which is available as a brand-name medication. GoodRx can help you navigate between copay savings cards and patient assistance programs to save money on your prescription.
Save with a copay savings card. If you have commercial insurance, you may be eligible to pay as little as $0 for Trelegy Ellipta using a savings card from the manufacturer.
Save with patient assistance programs. If you’re uninsured or underinsured, you may be eligible for Trelegy Ellipta’s patient assistance program, which offers the medication free of cost.
The bottom line
Trelegy Ellipta (fluticasone furoate / umeclidinium / vilanterol) is an inhaler that’s used for asthma and chronic obstructive pulmonary disease (COPD). The typical Trelegy Ellipta dosage is 1 puff once a day. Your specific dose depends on why you’re using the inhaler. And if you have asthma, your dose can be adjusted based on your symptoms.
Be sure to only use Trelegy Ellipta once every 24 hours. Using it more often than this raises your risk of side effects.
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References
GlaxoSmithKline. (2023). Trelegy Ellipta - fluticasone furoate, umeclidinium bromide and vilanterol trifenatate powder [package insert].
Hsu, E., et al. (2023). Beta2-agonists. StatPearls.
MedlinePlus. (2017). Umeclidinium oral inhalation.
MedlinePlus. (2020). Fluticasone, umeclidinium, and vilanterol oral inhalation.
Remien, K., et al. (2024). Fluticasone. StatPearls.
