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How Much Is Trelegy Ellipta Without Insurance?

Tamara E. HolmesJoshua Murdock, PharmD, BCBBS
Published on December 17, 2024

Key takeaways:

  • Trelegy Ellipta (fluticasone / umeclidinium / vilanterol) contains three active ingredients that decrease inflammation and relax the air passages in the lungs. The inhaler is used for the long-term treatment of chronic obstructive pulmonary disease (COPD) and asthma.

  • If you don’t have insurance, the amount you will pay for Trelegy Ellipta depends on where you live, your pharmacy, your dosage, and whether you qualify for any discounts or coupons. The average cost of one 100 mcg / 62.5 mcg / 25 mcg inhaler is about $824.55 without insurance.

  • You may be able to pay less for Trelegy Ellipta by using a GoodRx coupon or comparing prices at different pharmacies. You also may be able to save between $100 and $500 on your monthly prescriptions through GSK’s Trelegy savings program.

Access savings on related medications

A man is pictured using an asthma inhaler in a close-up.
tdub303/E+ via Getty Images

Having asthma or chronic obstructive pulmonary disease (COPD) can make breathing difficult, and for some people, lead to a poor quality of life. Trelegy Ellipta is a brand-name, once-daily inhaler that can help make it easier for people with these conditions to breathe. 

Trelegy Ellipta contains three active ingredients: fluticasone, umeclidinium, and vilanterol. Fluticasone decreases inflammation in the lungs, while umeclidinium and vilanterol relax the air passages in the lungs. Trelegy Ellipta is not a rescue inhaler, so it won’t relieve sudden or emergency breathing problems. Instead, it can offer long-term relief as a maintenance treatment.

Since Trelegy Ellipta utilizes three active ingredients and there is currently no generic version of the inhaler, it may cost more than some alternative medications. Without insurance or discounts, the average cost of one 100 mcg / 62.5 mcg / 25 mcg inhaler is around $824.55.

Promotion disclosure
Avg retail price
$894.18(Save 27.57%)
GoodRx discount
$647.63

Trelegy Ellipta basics

The chart below provides a summary of basic information about Trelegy Ellipta.

Trelegy Ellipta Basics

Brand name Trelegy Ellipta
Generic name No generic available
Available doses
  • 100 mcg / 62.5 mcg / 25 mcg
  • 200 mcg / 62.5 mcg / 25 mcg
Recommended dosages
  • For Asthma: One inhalation of the 100 mcg / 62.5 mcg / 25 mcg inhaler or the 200 mcg / 62.5 mcg / 25 mcg inhaler at the same time every day
  • For COPD: One inhalation of the 100 mcg / 62.5 mcg / 25 mcg inhaler at the same time every day
FDA-approved uses
Benefits
  • Three active ingredients in one device
  • Improved breathing for 24 hours per dose
  • Prevention of some asthma and COPD symptoms
Possible side effects
  • Headaches
  • Back pain
  • Changes in taste
  • Diarrhea
  • Constipation
  • Sore throat
  • Upper respiratory tract infections
  • Bronchitis
  • Pneumonia
  • Urinary tract infections
  • Joint pain
  • Mouth and throat pain
  • Hoarseness
  • Narrowing of the airways
  • Heart problems

Is Trelegy Ellipta covered by insurance?

The vast majority of health insurance plans cover Trelegy Ellipta. If you have insurance, check your plan’s summary of benefits and coverage and formulary to determine whether Trelegy Ellipta is covered.

If you have commercial insurance and your plan doesn’t fully cover Trelegy Ellipta, you may be able to save up to $500 per month for 3 months, or up to $200 per month for 9 months, with a copay savings card. You can join the Trelegy savings program to see if you are eligible for any discounts. Your healthcare professional can also order copay savings cards for their office.

How insurance covers Trelegy Ellipta

As mentioned, Trelegy Ellipta is covered for almost everyone with insurance. And most health insurance providers don’t require enrollees to get a prior authorization or do step therapy for Trelegy Ellipta. However, Medicaid requires a prior authorization for more than 70% of enrollees and step therapy for more than 40% of enrollees.

The following table shows the likelihood of having coverage, as well as prior authorization and step therapy requirements, for the Trelegy Ellipta 100 mcg / 62.5 mcg / 25 mcg inhaler with different types of insurance plans.

Insurance Coverage for Trelegy Ellipta

Insurance type

Enrollees covered for Trelegy Ellipta

Enrollees required to get a prior authorization

Enrollees required to do step therapy

Affordable Care Act (ACA) plans

95.9%

5.4%

2.62%

Commercial (not including ACA) plans

97.7%

5.3%

1.37%

Medicare, including original Medicare and Medicare Advantage plans

96%

0%

0.03%

Medicaid, including state-run and managed care plans

99.9%

72.1%

41.98%

Source: Managed Markets Insight & Technology, LLC™, as of November 13, 2024. (See methodology below.)

GoodRx icon
  • Trelegy Ellipta contains multiple medications. Trelegy Ellipta is a long-acting maintenance asthma inhaler that contains several medications to help people get a handle on their symptoms.

  • A guide to using Trelegy Ellipta inhalers: Learn how to use the inhalers for asthma or chronic obstructive pulmonary disease (COPD).

  • Comparing the costs of asthma inhalers: See how Trelegy Ellipta measures up to other inhalers and find out ways to save on your prescriptions.

Tips if your medication isn’t covered by insurance

If your insurance doesn’t cover Trelegy Ellipta, here are a few options to try:

  • Talk to your prescriber about alternative medications.

  • Ask for a formulary exception from your insurance plan. Keep in mind that you may be required to do step therapy or get a prior authorization to be covered.

  • If you request a formulary exception and it’s denied, file an appeal with your plan.

  • Use a GoodRx coupon for potential savings.

  • Consider changing your prescription medication coverage during your next open enrollment period.

  • Check if you’re eligible for savings through GSK’s patient assistance program for people without insurance. Or if you have commercial insurance, see if you qualify for a copay savings card.

How much does Trelegy Ellipta cost without insurance?

Without insurance, the average cost of one 100 mcg / 62.5 mcg / 25 mcg Trelegy Ellipta inhaler is about $824.55. However, the exact price you pay will depend on factors such as:

  • Your dosage

  • Your geographic location

  • Your specific pharmacy

Trelegy Ellipta Costs

Dosage form (1 inhaler)

Average cash price

100 mcg / 62.5 mcg / 25 mcg

$824.55

200 mcg / 62.5 mcg / 25 mcg

$835.99

Ways to save on Trelegy Ellipta without insurance

Below are six potential ways to save on Trelegy Ellipta without insurance.

1. Use a GoodRx coupon

With a GoodRx coupon, you may be able to pay a lower price for your Trelegy Ellipta prescription. At certain pharmacies, one 100 mcg / 62.5 mcg / 25 mcg inhaler may cost as low as $659.81 with a GoodRx coupon. 

Here’s how to get a coupon:

  • Visit www.goodrx.com or install the GoodRx app on your mobile device.

  • Type “Trelegy Ellipta” in the search field.

  • Select the correct dose and quantity, and set your location.

  • Click or tap on “Search prices” to find prices at pharmacies near you.

  • Choose to receive your coupon via text or email, or print it out.

  • Show the coupon at the pharmacy when you pick up your medication. Or present the coupon to your pharmacy staff early on in the filling process, such as when you first receive your prescription, to help prevent delays at the pick-up counter.

2. Request a larger supply

Ask your prescriber for a prescription for multiple inhalers. Filling multiple inhalers at once may reduce the cost for each individual inhaler. 

If you have insurance that covers Trelegy Ellipta, you can also ask about potential discounts for using your plan’s mail-order pharmacy.

3. Compare prices at various pharmacies

GoodRx can help you easily compare costs at different pharmacies so that you can find the best Trelegy Ellipta price in your area.

4. Ask your prescriber about alternatives

If you are concerned about the cost of Trelegy Ellipta, talk to your prescriber. There may be another medication that adequately treats your condition and fits your budget.

5. Use funds from a tax-advantaged account

If you have a health savings account (HSA), a flexible spending account (FSA) or a health reimbursement arrangement (HRA), using those funds to buy your medication can reduce your out-of-pocket costs through tax savings.

6. See if you're eligible for a patient assistance program

GSK, the manufacturer of Trelegy Ellipta, offers a patient assistance program for people without insurance, as well as assistance through its patient access foundation.

The bottom line

Trelegy Ellipta (fluticasone / umeclidinium / vilanterol) is a maintenance inhaler that is used for the long-term treatment of chronic obstructive pulmonary disease (COPD) and asthma. It contains three active ingredients that, together, help decrease inflammation and relax the air passages in the lungs. 

Even without insurance, there are ways to save on Treley Ellipta. For example, the cost of one 100 mcg / 62.5 mcg / 25 mcg inhaler may be as low as $659.81 with a GoodRx coupon at certain pharmacies. And GSK, the maker of Trelegy Ellipta, offers multiple programs to help consumers reduce their out-of-pocket costs.

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Why trust our experts?

Tamara E. Holmes
Written by:
Tamara E. Holmes
Tamara E. Holmes is a Washington, DC-based freelance journalist and content strategist who has been writing about personal finance, health, and health insurance for more than a decade. Her work has appeared in various print and online publications, such as USA Today, AARP, Working Mother, and Diversity Woman.
Cindy George, MPH
Cindy George is the senior personal finance editor at GoodRx. She is an endlessly curious health journalist and digital storyteller.
Joshua Murdock, PharmD, BCBBS
Joshua Murdock, PharmD, BCBBS, is a licensed pharmacist in Arizona, Colorado, and Rhode Island. He has worked in the pharmacy industry for more than 10 years and currently serves as a pharmacy editor for GoodRx.

Methodology

We obtained national prescription coverage data for each medication from Managed Markets Insight & Technology (MMIT). The data reflects health insurance coverage as of November 2024. 

We calculated the percentage of enrollees in plans that cover each medication by dividing the number of enrollees covered for the medication within a specific insurance channel (e.g., ACA, Medicare, Medicaid) by the total number of enrollees in all plans within that channel. 

We determined the percentage of enrollees in plans with a prior authorization requirement by calculating the proportion of enrollees in plans that required prior authorization for the medication within each channel. 

Finally, we measured the percentage of enrollees in plans with a step therapy requirement by calculating the proportion of enrollees in plans that imposed step therapy requirements for the medication in each channel. 

These estimates, derived from national MMIT coverage data, provide insight into health insurance coverage for each medication. They take into account restrictions such as prior authorization, step therapy, and quantity limits. The percentages are expressed relative to the total number of enrollees covered by various insurance channels, including ACA plans, commercial (excluding ACA) plans, Medicare, and Medicaid (both state-run and managed care plans).

View All References (3)

Medicaid.gov. (n.d.). Managed care. Centers for Medicare & Medicaid Services. 

Trelegy Ellipta. (n.d.). Request Trelegy samples and savings offers.

Trelegy Ellipta. (n.d.). Trelegy: Savings and support.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

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