Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Budesonide/formoterol (Symbicort) and albuterol (ProAir HFA, Ventolin HFA) are both inhaled medications used to treat breathing problems, but they have some important differences. Budesonide/formoterol is a combination of a corticosteroid and a long-acting beta-agonist (LABA), while albuterol is a short-acting beta-agonist (SABA). Budesonide/formoterol is used for long-term management of asthma and chronic obstructive pulmonary disease (COPD) and is used twice a day regularly. On the other hand, albuterol is a rescue inhaler used as needed for sudden wheezing or shortness of breath. It works within minutes and lasts up to 6 hours. Budesonide/formoterol is available in two strengths. Albuterol comes in one strength but multiple brand names and forms, including HFA and dry powder inhalers. Budesonide/formoterol can cause an oral fungal infection called thrush. You can reduce your risk for thrush by rinsing your mouth out with water and spitting it out after each use. Albuterol may cause sore throat and throat irritation. Budesonide/formoterol should not be used for asthma attacks, while albuterol is specifically designed for sudden shortness of breath or wheezing.
Symbicort (budesonide / formoterol)
Albuterol
Symbicort (budesonide / formoterol)
Albuterol
Summary of Symbicort vs. Albuterol
Summary for Inhaled corticosteroid / LABA
Prescription only
Symbicort (budesonide / formoterol) is a combination inhaler used to treat asthma and chronic obstructive pulmonary disease (COPD). It contains two medications: budesonide, a steroid, and formoterol, a long-acting beta-agonist (LABA). Both medications work together to reduce inflammation in the lungs and open up your airways. The typical dose is two puffs by mouth twice a day, usually about 12 hours apart. Common side effects include common cold symptoms, headache, and sore throat.
Summary for SABA
Prescription only
Albuterol sulfate is a short-acting beta agonist (SABA). It's a rescue inhaler that treats or prevents sudden wheezing or shortness of breath in adults and children at least 4 years old with certain breathing problems, such as asthma. Albuterol is inhaled through the mouth using either an HFA inhaler (or metered dose inhaler) or a dry powder inhaler. The typical dose is 2 inhalations every 4 to 6 hours as needed when you suddenly have trouble breathing. Albuterol side effects generally include sore throat, throat irritation, and infections.
Indications of Symbicort vs. Albuterol
Indications for
•Asthma - in adults and children 6 years and older