Key takeaways
Budesonide/formoterol (Symbicort) and albuterol (ProAir HFA, Ventolin HFA) are both inhaled medications used to treat breathing problems, but they have some important differences. Budesonide/formoterol is a combination of a corticosteroid and a long-acting beta-agonist (LABA), while albuterol is a short-acting beta-agonist (SABA). Budesonide/formoterol is used for long-term management of asthma and chronic obstructive pulmonary disease (COPD) and is used twice a day regularly. On the other hand, albuterol is a rescue inhaler used as needed for sudden wheezing or shortness of breath. It works within minutes and lasts up to 6 hours. Budesonide/formoterol is available in two strengths. Albuterol comes in one strength but multiple brand names and forms, including HFA and dry powder inhalers. Budesonide/formoterol can cause an oral fungal infection called thrush. You can reduce your risk for thrush by rinsing your mouth out with water and spitting it out after each use. Albuterol may cause sore throat and throat irritation. Budesonide/formoterol should not be used for asthma attacks, while albuterol is specifically designed for sudden shortness of breath or wheezing.
