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PDE4 Inhibitors

PDE4 inhibitors are used to treat COPD, eczema and psoriasis. They work by reducing inflammation in the lungs and skin.

Why are pde4 inhibitors prescribed?

  1. COPD (87%)
  2. Eczema (7%)
  3. Plaque Psoriasis (5%)
  4. Psoriatic Arthritis (1%)
  5. Seborrheic Dermatitis (0%)

Key takeaways

PDE4 inhibitors are used to treat certain medical conditions that involve inflammation. Some PDE4 inhibitors help treat chronic obstructive pulmonary disease (COPD), while others help manage eczema, psoriasis, and psoriatic arthritis. These medications work by blocking the enzyme phosphodiesterase-4 (PDE4), which helps reduce inflammation in your body. PDE4 inhibitors come in different forms, including oral tablets and topical creams. Examples include roflumilast (Daliresp) for COPD, apremilast (Otezla) for psoriasis and psoriatic arthritis, and Eucrisa (crisaborole) for eczema. These treatments help manage your condition effectively.

Prices for popular PDE4 Inhibitors medications
Viewing 4 of 4 medications
ROFLUMILAST treats chronic obstructive pulmonary disease (COPD). It works by decreasing inflammation of the airways, making it easier to breathe. Do not use it to treat a sudden COPD flare-up.
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Eucrisa

as low as$766
CRISABOROLE reduces swelling, redness, itching, or rashes caused by skin conditions, such as eczema. It works by slowing down an overactive immune system.
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Zoryve

as low as$895
Zoryve (roflumilast) is used to treat plaque psoriasis, seborrheic dermatitis and mild to moderate eczema. There are currently no generic alternatives for Zoryve. It may be covered by your Medicare or insurance plan, but some pharmacy coupons or cash prices could help offset the cost.
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Subject to eligibility
Otezla (apremilast) is used to treat psoriasis and psoriatic arthritis. Otezla is a PDE4 Inhibitor, which works by reducing inflammation in the lungs. The most common form of Otezla is a 30mg tablet. It's also available in titration packs. It is available in both generic and brand versions. It is covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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