Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Eucrisa vs. Temovate

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Eucrisa (crisaborole) and Clobetasol are both used to treat skin conditions, but they have some key differences. Eucrisa (crisaborole) is a PDE4 inhibitor used to treat mild-to-moderate eczema in people 3 months and older. It is only available as a brand medication and is applied as an ointment twice daily. Clobetasol, on the other hand, is a super potent corticosteroid used for more severe skin problems like psoriasis and eczema. It comes in various forms, including cream, shampoo, and spray, and is generally for short-term use due to potential serious side effects like skin thinning and high blood sugar. Clobetasol is available as a lower-cost generic medication and some formulations (solution and foam) can be used by children as young as 12 years old. While Eucrisa can be used safely in young children, Clobetasol is more potent and is used for more severe conditions but with more caution due to its stronger effects and potential risks.

  • Eucrisa (crisaborole)
    Clobetasol
  • Eucrisa (crisaborole)
    Clobetasol

  • Summary of Eucrisa vs. Temovate

    Summary for PDE4 inhibitor
    Prescription only

    Eucrisa (crisaborole) is an ointment that's used to treat eczema for people 3 months and older. The medication is a phosphodiesterase 4 (PDE4) inhibitor that works to help reduce skin inflammation and itching from eczema. The ointment is usually applied to the affected area(s) of skin twice a day. The most common side effect is burning or stinging on the skin where you apply the medication.

    Summary for Corticosteroid
    Prescription only

    Clobetasol is a super potent (very strong) steroid medication that's applied to the skin. It's used to relieve skin inflammation and irritation caused by moderate to severe skin problems, such as psoriasis. Clobetasol is available in many different formulations, including cream, shampoo, lotion, and spray. Most formulations of clobetasol aren't recommended to be used for more than 2 weeks at a time since it can cause serious side effects. In general, clobetasol is for adults only, but some formulations (e.g., solution and foam) can be used by children as young as 12 years old.

  • Indications of Eucrisa vs. Temovate

    Indications for
    •Mild-to-moderate eczema
    Indications for
    •Treatment of skin rashes and itchy skin - all topical forms except shampoo
    •Treatment of moderate to severe scalp psoriasis - foam and shampoo only
    •Treatment of plaque psoriasis not on the scalp - all topical forms except shampoo

  • Pros and Cons of Eucrisa vs. Temovate

    Pros and Const for PDE4 inhibitor
    Pros
    •Easy-to-apply ointment
    •Safe to use on children as young as 3 months old
    •Can start to see improvement in your skin in about 1 week
    •An alternative to topical steroids to treat eczema
    Cons
    •Must use twice daily
    •Can cause pain, burning, or stinging on the skin
    •Not approved for severe eczema
    •No lower-cost generic available
    Pros and Const for Corticosteroid
    Pros
    •Available as a lower-cost, generic medication
    •One of the most potent (high strength) topical steroids
    •Many formulations to choose from, such as ointment, cream, and spray
    •Works well to manage psoriasis symptoms
    Cons
    •For short-term use only, otherwise it might cause skin thinning and high blood sugar
    •Not safe to use on the face, armpits, or groin
    •Certain products aren't safe for children under 12 years old (shampoo, lotion, and spray can only be used by adults)
    •Unknown if safe in pregnant or breastfeeding females

  • Common Side Effects of Eucrisa vs. Temovate

    Common Side Effects for
    •Pain, burning, or stinging where the medication is applied (4%)
    Common Side Effects for
    •Burning
    •Stinging
    •Skin irritation
    •Itching

  • Warnings of Eucrisa vs. Temovate

    Common Side Effects for
    •Allergic reactions
    Common Side Effects for
    •Changes in hormone levels
    •Risk of high blood sugar
    •New or worsened skin infection
    •Skin problems

  • Prices with our coupons for Eucrisa vs. Temovate

    Learn more about Eucrisa
    Learn more about Clobetasol

Compare other Eczema drugs

Eucrisa vs DupixentEucrisa vs ElidelEucrisa vs TemovateDupixent vs AdbryDupixent vs FasenraDupixent vs SymbicortDupixent vs XolairEbglyss vs DupixentEntyvio vs RinvoqEohilia vs DupixentEticovo vs RinvoqNucala vs DupixentOhtuvayre vs DupixentOlumiant vs RinvoqOrencia vs RinvoqRemicade vs RinvoqRinvoq vs ActemraRinvoq vs CibinqoRinvoq vs CimziaRinvoq vs CosentyxRinvoq vs DupixentRinvoq vs EnbrelRinvoq vs HumiraRinvoq vs OtezlaRinvoq vs SimponiRinvoq vs SkyriziRinvoq vs XeljanzSkyrizi vs DupixentTezspire vs DupixentTremfya vs Dupixent
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.