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Eucrisa vs. Clobetasol

Eucrisa (crisaborole) is an ointment that's used to treat eczema for people 3 months and older. The medication is a phosphodiesterase 4 (PDE4) inhibitor that works to help reduce skin inflammation and itching from eczema. The ointment is usually applied to the affected area(s) of skin twice a day. The most common side effect is burning or stinging on the skin where you apply the medication.

• Mild-to-moderate eczema

• Pain, burning, or stinging where the medication is applied (4%)

• Allergic reactions

Clobetasol is a super potent (very strong) corticosteroid that's applied to the skin. It helps relieve skin inflammation and irritation from moderate-to-severe skin problems, like psoriasis. Clobetasol is available in many different formulations. This includes a cream, ointment, shampoo, topical solution, and foam. Most formulations are for people 12 years and older. But others, like the shampoo and lotion, are for adults only. Some side effects include burning, stinging, and irritation where it's applied. Clobetasol has both brand-name and generic options.

• Skin rashes and itchy skin - all topical forms except shampoo
• Plaque psoriasis not on the scalp - all topical forms except shampoo
• Moderate-to-severe scalp psoriasis - shampoo and certain foams only

• Burning
• Stinging
• Skin irritation
• Itching

• More skin reactions with longer use and coverings
• Changes in stress hormone levels
• Topical steroid withdrawal
• Higher risk of cataracts and glaucoma
• Treat any skin infections appropriately
• Flammable (clobetasol foam, solution, and spray only)