Eucrisa vs. Tacrolimus for Eczema: Important Differences and Potential Risks.

Eucrisa

(crisaborole)

Tacrolimus

(Protopic)

Summary for Eucrisa

Prescription only

Eucrisa (crisaborole) is a steroid-free ointment that's used to treat eczema. It's approved for adults and children ages 3 months and older. This medication is a phosphodiesterase 4 (PDE4) inhibitor that works to help reduce skin inflammation and itching from eczema. The ointment is usually applied to the affected area(s) of skin twice a day. The most common side effect is burning or stinging on the skin where you apply the medication.

Indications for Eucrisa

Mild-to-moderate eczema

Pros and Cons for Eucrisa

Pros

Easy-to-apply ointment
Can be used on children as young as 3 months old
An alternative to topical steroids for treating eczema
Safe for long-term use

Cons

Must use twice a day at first
Can cause pain, burning, or stinging on the skin where you applied the medication
Might not start to see improvement for about 1 week or longer
Not approved for severe eczema

Common Side Effects for Eucrisa

Pain, burning, or stinging where the medication is applied (4%)

Warnings for Eucrisa

Allergic reactions

Summary for Tacrolimus

Prescription only

Tacrolimus (Protopic) is a prescription non-steroid ointment used short-term on the skin to treat moderate-to-severe eczema (atopic dermatitis). It's a calcineurin inhibitor that helps lower the immune system’s response so it doesn’t cause inflammation and make eczema worse. Tacrolimus (Protopic) is approved for both adults and children ages 2 years and older who don't have a weakened immune system. It comes as both a brand-name and generic ointment that you apply to the affected area twice daily. Common side effects include stinging, itching, and a burning sensation at the application site.

Indications for Tacrolimus

Moderate-to-severe eczema in adults and children ages 2 years and older

Pros and Cons for Tacrolimus

Pros

Non-steroid option for treating eczema
Usually starts to work as early as 1 week
Can be used in both adults and children
Can be applied to the face, neck, groin, around the eyes, or in skin folds

Cons

Not a first-choice medication for treating eczema
Typically only used short term
Can cause burning and stinging where you apply it
Unknown if safe during pregnancy or while breastfeeding

Common Side Effects for Tacrolimus

Adults:

Skin burning (up to 58%)
Itchiness (up to 46%)
Flu-like symptoms (up to 31%)
Skin redness (up to 28%)
Headache (up to 20%)

Children:

Skin burning (up to 43%)
Itchiness (up to 41%)
Flu-like symptoms (up to 34%)

Warnings for Tacrolimus

Long-term use and risk of cancer
Risk of infection
Swollen lymph nodes
Sun exposure
Sudden kidney failure

Prices with our coupons for Eucrisa vs. Tacrolimus

Eucrisa1 tube / 60g of 2%

$158.48$938.99

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Tacrolimus1 tube / 60g of 0.1%

$54.18$465.02

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Eucrisa vs. Tacrolimus

Eucrisa

Tacrolimus

Summary for Eucrisa

Indications for Eucrisa

Pros and Cons for Eucrisa

Pros

Cons

Common Side Effects for Eucrisa

Warnings for Eucrisa

Summary for Tacrolimus

Indications for Tacrolimus

Pros and Cons for Tacrolimus

Pros

Cons

Common Side Effects for Tacrolimus

Warnings for Tacrolimus

Prices with our coupons for Eucrisa vs. Tacrolimus

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Eucrisa

Tacrolimus

Summary for Eucrisa

Indications for Eucrisa

Pros and Cons for Eucrisa

Pros

Cons

Common Side Effects for Eucrisa

Warnings for Eucrisa

Summary for Tacrolimus

Indications for Tacrolimus

Pros and Cons for Tacrolimus

Pros

Cons

Common Side Effects for Tacrolimus

Warnings for Tacrolimus