Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Clotrimazole (Lotrimin AF) and triamcinolone (Triderm) are both topical medications used to treat skin conditions, but they belong to different medication classes. Clotrimazole is an antifungal medication used to treat fungal infections like athlete's foot, jock itch, and ringworm. It is available over-the-counter and is applied twice daily. Triamcinolone, on the other hand, is a prescription-only corticosteroid used to treat inflammatory skin conditions such as eczema and psoriasis. It is available in various forms, including creams and sprays, and is typically applied 2 to 4 times a day. While clotrimazole is generally well-tolerated with mild skin irritation as a possible side effect, triamcinolone can cause more serious side effects like skin thinning and adrenal suppression if used improperly. Clotrimazole is safe for use in children over 2 years old, while triamcinolone requires careful monitoring in children due to the risk of side effects. Additionally, triamcinolone should not be used on fungal infections, as it can worsen them, whereas clotrimazole is specifically designed to treat such infections.
Clotrimazole (Lotrimin AF)
Triamcinolone
Clotrimazole (Lotrimin AF)
Triamcinolone
Summary of Clotrimazole vs. Triamcinolone
Summary for Antifungal
Clotrimazole (Lotrimin AF) is an over-the-counter (OTC) antifungal cream that's applied to the skin to treat certain infections, such as ringworm and athlete's foot. Sometimes, a provider might also recommend this medication for diaper rash. Clotrimazole (Lotrimin AF) is for adults and children 2 years and older, unless otherwise directed by a provider. Most people experience few to no side effects while using clotrimazole (Lotrimin AF), though mild skin irritations have been reported.
Summary for Corticosteroid
Prescription only
Triamcinolone is a topical corticosteroid used to treat different inflammatory skin conditions, like eczemapsoriasis, or skin allergies, in adults and children. It works by reducing inflammation, redness, and irritation. The medication is available in various formulations, such as cream, ointment, lotion, and topical spray. Depending on the formulation, it's typically applied between 2 to 4 times a day. Side effects are rare, but can include burning, itching, and dryness at the application site.
Indications of Clotrimazole vs. Triamcinolone
Indications for
Treatment and symptom relief (e.g., itching, irritation, redness) of the following fungal skin infections: