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Compare Sporanox vs. Terbinafine

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Itraconazole (Sporanox) capsule
    Terbinafine
  • Itraconazole (Sporanox) capsule
    Terbinafine

  • Summary of Sporanox vs. Terbinafine

    Summary for Antifungal
    Prescription only

    Itraconazole (Sporanox) capsule is used to treat various fungal infections. You might have to take it for several weeks or months. It interacts with many medications, which can lead to serious heart-related side effects.

    Summary for Antifungal
    Prescription only

    Terbinafine is a first-choice treatment option for fingernail and toenail fungus. It's available as once-daily tablets, but treatment can take many weeks. Common side effects of terbinafine include headache, rash, diarrhea, and upset stomach. Terbinafine can have interactions with other medications, including certain antidepressants, beta-blockers, and some medications that treat an irregular heart rhythm.

  • Indications of Sporanox vs. Terbinafine

    Indications for

    Severe fungal infections in people with weakened or healthy immune systems - itraconazole (Tolsura) and itraconazole (Sporanox) capsule:

    •Blastomycosis
    •Histoplasmosis
    •Aspergillosis in people in which amphotericin b (Ambisome) hasn't worked or isn't tolerated

    Fungal toenail and fingernail infections (onychomycosis) for people with healthy immune systems - itraconazole (Sporanox) capsule only

    Indications for
    •Fungal infection of toenail or fingernail

  • Pros and Cons of Sporanox vs. Terbinafine

    Pros and Const for Antifungal
    Pros
    •Works to treat some serious and life-threatening fungal infections
    •Available as a lower-cost generic
    •Can be taken once a day for most conditions
    Cons
    •Can raise your risk for serious heart problems, including heart failure
    •Must be taken for several weeks to months
    •Interacts with many medications
    Pros and Const for Antifungal
    Pros
    •Works better to treat nail fungus than other treatment options
    •First-choice over other antifungal medications that are taken by mouth (e.g., versus itraconazole (Sporanox))
    •Only taken once a day, with or without food
    •Lower-cost generic available
    Cons
    •Can take several weeks to work
    •Can cause loss of taste or smell (sometimes permanently)
    •Not recommended if you have long-term or current liver problems
    •Not studied in children

  • Common Side Effects of Sporanox vs. Terbinafine

    Common Side Effects for
    •Nausea (11%)
    •Rash (3-9%)
    •Vomiting (5%)
    •Swelling in the arms and legs (4%)
    •Headache (1-4%)
    Common Side Effects for
    •Headache (13%)
    •Rash (6%)
    •Diarrhea (6%)
    •Upset stomach (4%)

  • Warnings of Sporanox vs. Terbinafine

    Common Side Effects for
    •Congestive heart failure (CHF)
    •Abnormal heart rhythm (QT prolongation)
    •Liver damage
    •Interactions with other medications
    •Hearing loss
    •Vision problems
    •Nerve damage (peripheral neuropathy)
    Common Side Effects for
    •Liver damage
    •Changes to taste and smell
    •Depression
    •Low white blood cell levels
    •Serious skin reactions
    •Lupus flare up
    •Clotting and bleeding problems

  • Prices with our coupons for Sporanox vs. Terbinafine

    Learn more about Itraconazole
    Learn more about Terbinafine

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