Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Nystatin (Nystop, Nyamyc, Klayesta) and clotrimazole (Lotrimin AF) are both antifungal medications, but they have some key differences. Nystatin is available by prescription only and is used to treat yeast infections on the skin. It comes in various forms like cream, ointment, and powder, and is safe for all ages, including babies. On the other hand, clotrimazole is available over-the-counter and treats a wider range of fungal infections, such as athlete's foot, jock itch, and ringworm. Clotrimazole is suitable for adults and children over 2 years old. While both medications are generally well-tolerated, nystatin is specifically for yeast infections, whereas clotrimazole can treat multiple types of fungal infections. Additionally, clotrimazole might take up to a month to fully treat certain infections, whereas nystatin can start working within a few days.
Nystatin topical is a prescription antifungal you use on your skin to treat certain fungal skin infections, like yeast infections. It's safe for all ages, even babies with diaper rash. Nystatin topical comes as a cream, ointment, or powder. You usually apply it to the affected skin 2 to 3 times a day. Sometimes, it can cause mild side effects like itching or burning where you put it on.
Summary for Antifungal
Clotrimazole (Lotrimin AF) is an over-the-counter (OTC) antifungal cream that's applied to the skin to treat certain infections, such as ringworm and athlete's foot. Sometimes, a provider might also recommend this medication for diaper rash. Clotrimazole (Lotrimin AF) is for adults and children 2 years and older, unless otherwise directed by a provider. Most people experience few to no side effects while using clotrimazole (Lotrimin AF), though mild skin irritations have been reported.