Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Sporanox vs. Oravig

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Itraconazole (Sporanox, Tolsura) and miconazole (Oravig) are both antifungal medications used to treat fungal infections, but they differ in their specific uses and forms. Itraconazole is available in oral capsules and is used for severe fungal infections like blastomycosis, histoplasmosis, and aspergillosis, as well as fungal nail infections. Miconazole, on the other hand, is available as a buccal tablet and is specifically used for oral thrush in the mouth and throat. While itraconazole is taken with food and can be used for several months, miconazole is placed in the mouth once daily for 14 days. Itraconazole is available as a generic, making it more affordable, whereas miconazole does not have a generic version. Common side effects of itraconazole include nausea and rash, while miconazole may cause mouth discomfort and diarrhea. Itraconazole has significant drug interactions and can cause serious heart-related side effects, whereas miconazole's main concern is potential allergic reactions.

  • Itraconazole (Sporanox) capsule
    Oravig (miconazole)
  • Itraconazole (Sporanox) capsule
    Oravig (miconazole)

  • Summary of Sporanox vs. Oravig

    Summary for Antifungal
    Prescription only

    Itraconazole (Sporanox) capsule is used to treat various fungal infections. You might have to take it for several weeks or months. It interacts with many medications, which can lead to serious heart-related side effects.

    Summary for Antifungal
    Prescription only

    Oravig (miconazole) treats fungal infections in the mouth and throat (oral thrush). This medication comes as a tablet that dissolves against your gum in your mouth, so it might be more difficult to use than other medications. The most common side effects of Oravig (miconazole) include upset stomach (e.g., diarrhea, nausea) and headache.

  • Indications of Sporanox vs. Oravig

    Indications for

    Severe fungal infections in people with weakened or healthy immune systems - itraconazole (Tolsura) and itraconazole (Sporanox) capsule:

    •Blastomycosis
    •Histoplasmosis
    •Aspergillosis in people in which amphotericin b (Ambisome) hasn't worked or isn't tolerated

    Fungal toenail and fingernail infections (onychomycosis) for people with healthy immune systems - itraconazole (Sporanox) capsule only

    Indications for
    •Oral thrush of the mouth and throat

  • Pros and Cons of Sporanox vs. Oravig

    Pros and Const for Antifungal
    Pros
    •Works to treat some serious and life-threatening fungal infections
    •Available as a lower-cost generic
    •Can be taken once a day for most conditions
    Cons
    •Can raise your risk for serious heart problems, including heart failure
    •Must be taken for several weeks to months
    •Interacts with many medications
    Pros and Const for Antifungal
    Pros
    •First and only tablet for oral thrush that dissolves against the gum in the mouth
    •Only need to take once daily
    •No serious side effects
    Cons
    •Can be tricky to use compared to other medications
    •Can take 6 or more hours to fully dissolve
    •No lower-cost generic available

  • Common Side Effects of Sporanox vs. Oravig

    Common Side Effects for
    •Nausea (11%)
    •Rash (3-9%)
    •Vomiting (5%)
    •Swelling in the arms and legs (4%)
    •Headache (1-4%)
    Common Side Effects for
    •Mouth discomfort (e.g., pain, swelling; up to 12%)
    •Diarrhea (9%)
    •Headache (8%)
    •Nausea (7%)
    •Vomiting (4%)

  • Warnings of Sporanox vs. Oravig

    Common Side Effects for
    •Congestive heart failure (CHF)
    •Abnormal heart rhythm (QT prolongation)
    •Liver damage
    •Interactions with other medications
    •Hearing loss
    •Vision problems
    •Nerve damage (peripheral neuropathy)
    Common Side Effects for
    •Allergic reaction

  • Prices with our coupons for Sporanox vs. Oravig

    Learn more about Itraconazole
    Learn more about Oravig

Compare other Nail Fungus and Thrush drugs

Itraconazole vs AmbisomeItraconazole vs ClotrimazoleItraconazole vs DiflucanItraconazole vs EconazoleItraconazole vs KetoconazoleItraconazole vs NystatinItraconazole vs OravigItraconazole vs TerbinafineNoxafil vs ItraconazoleClotrimazole vs KetoconazoleClotrimazole vs TriamcinoloneDiflucan vs NystatinDiflucan vs SporanoxKetoconazole vs CresembaKetoconazole vs DiflucanKetoconazole vs EconazoleKetoconazole vs NoxafilKetoconazole vs OravigKetoconazole vs TriamcinoloneMupirocin vs NystatinNoxafil vs AmbisomeNoxafil vs DiflucanNystatin vs ClotrimazoleNystatin vs EconazoleNystatin vs OravigTerbinafine vs ClotrimazoleTerbinafine vs NystatinTerbinafine vs OravigVfend vs DiflucanVfend vs Noxafil
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.