Key takeaways
Terbinafine (Lamsil) and nystatin are both antifungal medications, but they have different uses and forms. Terbinafine is taken orally and is primarily used to treat fungal infections of the fingernails and toenails. It is a first-choice treatment for these infections and is taken once daily for several weeks. Common side effects include headache, rash, and upset stomach. Nystatin, on the other hand, is used topically to treat fungal skin infections, such as yeast infections. It comes in various forms like cream, ointment, and powder, and is applied directly to the skin multiple times a day. Nystatin is generally well-tolerated, but some people may experience itching or burning at the application site. While terbinafine can interact with other medications and has potential serious side effects like liver damage, nystatin is considered safer for a wider range of people, including babies. Both medications are available in generic versions, but only terbinafine has over-the-counter topical forms available.
