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Compare Diflucan vs. Nyamyc

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Fluconazole (Diflucan) and nystatin (Nystop, Nyamyc, Klayesta) are both antifungal medications, but they have some key differences. Fluconazole is an azole antifungal that can be taken orally or by injection to treat various *Candida* infections, including vaginal yeast infections, oral thrush, and even serious infections like cryptococcal meningitis. It is usually taken once daily and is available as a lower-cost generic. On the other hand, nystatin is used topically to treat fungal skin infections, such as diaper rash, and comes in forms like cream, ointment, and powder. Nystatin is applied multiple times a day and is also available as a lower-cost generic. While fluconazole can cause side effects like headache and nausea and has a rare risk of liver problems, nystatin is generally well-tolerated but can cause local irritation like burning and itching. Additionally, fluconazole is not recommended during pregnancy due to potential risks, whereas the safety of nystatin during pregnancy or breastfeeding is not clearly established.

  • Fluconazole (Diflucan)
    Nystatin topical
  • Fluconazole (Diflucan)
    Nystatin topical

  • Summary of Diflucan vs. Nyamyc

    Summary for Antifungal
    Prescription only

    Fluconazole (Diflucan) is an azole antifungal. It's used to treat different types of Candida infections, such as vaginal yeast infections and oral thrush. It can also treat a serious brain infection called cryptococcal meningitis. Oral fluconazole (Diflucan) is available as a tablet and suspension. It's taken by mouth as a one-time dose for vaginal yeast infections; it's typically taken once daily for other types of infections. Fluconazole (Diflucan) is generally well-tolerated, but some people can experience side effects like headache, nausea, and stomach pain. Fluconazole (Diflucan) can raise the risk of liver problems, so you're recommend to avoiding drinking alcohol while taking this medication.

    Summary for Antifungal
    Prescription only

    Nystatin topical is a prescription antifungal you use on your skin to treat certain fungal skin infections, like yeast infections. It's safe for all ages, even babies with diaper rash. Nystatin topical comes as a cream, ointment, or powder. You usually apply it to the affected skin 2 to 3 times a day. Sometimes, it can cause mild side effects like itching or burning where you put it on.

  • Indications of Diflucan vs. Nyamyc

    Indications for
    •Treatment of infections caused by Candida:
    •Vaginal yeast infections
    •Mouth, throat, or esophagus infections, including oral thrush
    •Bloodstream infections
    •Urinary tract infections (UTIs)
    •Peritonitis (infection of the lining of the stomach)
    •Pneumonia
    •Prevention of Candida fungal infections for people having a bone marrow transplant
    •Cryptococcus meningitis
    Indications for
    •Fungal skin infections, like yeast infections

  • Pros and Cons of Diflucan vs. Nyamyc

    Pros and Const for Antifungal
    Pros
    •Taken once daily for most infections
    •Considered acceptable to take while breastfeeding
    •Oral liquid comes flavored for better taste
    •Available as a lower-cost generic
    Cons
    •Interacts with many medications
    •Not recommended during pregnancy due to the potential risk of harm to babies
    •Rare risk of liver problems
    Pros and Const for Antifungal
    Pros
    •Comes as an ointment, cream, and powder
    •Generally well-tolerated with few side effects
    •Safe for all ages, including babies
    Cons
    •Applied onto skin multiple times a day
    •Only treats some fungal skin infections, not bacteria or viruses
    •Need a prescription to get it

  • Common Side Effects of Diflucan vs. Nyamyc

    Common Side Effects for

    Single dose for vaginal yeast infection:

    •Headache (13%)
    •Nausea (7%)
    •Stomach pain (6%)
    •Diarrhea (3%)

    Multiple doses for other infections:

    •Nausea (4%)
    •Headache (2%)
    •Skin rash (2%)
    •Vomiting (2%)
    •Stomach pain (2%)
    •Diarrhea (2%)
    Common Side Effects for
    •Burning or pain where applied
    •Itching
    •Rash
    •Eczema

  • Warnings of Diflucan vs. Nyamyc

    Common Side Effects for
    •Liver damage
    •Allergic reaction
    •Severe skin reaction
    •Harm to unborn babies
    Common Side Effects for
    •Use only on your skin

  • Prices with our coupons for Diflucan vs. Nyamyc

    Learn more about Fluconazole
    Learn more about Nystatin topical

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