Azole antifungals are used to treat fungal infections such as skin infections, oral thrush, and vaginal yeast infections. They also have additional uses, including treating other candidiasis infections, aspergillosis, and certain types of fungal meningitis. These medications kill fungi by blocking them from making ergosterol, an essential component of fungal cell membranes. Azole antifungals come in various forms, including oral tablets, topical creams, and injections. Examples include fluconazole (Diflucan), ketoconazole, itraconazole (Sporanox), and voriconazole (Vfend). You can choose the form that best fits your needs based on the type and location of the infection.