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luliconazole

Generic Luzu
Used for Athlete's Foot, Ringworm, Jock Itch
Used for Athlete's Foot, Ringworm, Jock Itch

Luliconazole (Luzu) is an antifungal cream that treats fungal skin infections, such as tinea pedis (athlete's foot), tinea cruris (jock itch), and tinea corporis (body ringworm). It can be used on adults and children 2 years and older, depending on the condition. It's typically applied to the affected areas on the skin once a day. The most common side effect is mild application site reactions like burning, stinging, and redness.

Reviewed by:
reviewer
Kristianne Hannemann, PharmD
reviewer
Daisy Chau, PharmD
Last reviewed on November 22, 2024
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageCostAlternativesReferencesPricesMedicare
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What is Luliconazole (Luzu)?

What is Luliconazole (Luzu) used for?

How Luliconazole (Luzu) works

Luliconazole (Luzu) is an antifungal medication. It works by damaging the protective covering of the fungus. This stops the growth of the fungus and kills it to treat the infection.

Drug Facts

Common BrandsLuzu
Drug ClassAntifungal
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Avg retail price
$250.51(save 61.26%)
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$97.05
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What are the side effects of Luliconazole (Luzu)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Application site reactions (e.g. burning, stinging, redness, itchiness) (<1%)

Other Side Effects

Source: DailyMed

The following side effects have also been reported

Side effects that you should report to your care team as soon as possible:

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Mild skin irritation, redness, or dryness
pros-and-cons

Pros and cons of Luliconazole (Luzu)

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Pros

Applied once a day and for a shorter period of time than similar medications

Few side effects

Applied directly to the affected areas of skin

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Cons

Requires a prescription from a healthcare professional

Not approved to treat all types of fungal infections

Unknown if safe during pregnancy or while breastfeeding

pharmacist-tips

Pharmacist tips for Luliconazole (Luzu)

pharmacist

  • Apply a thin layer of luliconazole (Luzu) to the affected skin and surrounding area, gently rubbing it in until fully absorbed. Be sure to cover about 1 inch around the visible fungal infection to treat nearby areas that might have an early infection.

    • Wash your hands with soap and water after using luliconazole (Luzu) to avoid spreading the fungal infection and prevent the medication from getting into your eyes. If it does get in your eyes, rinse them well with water.

      • Use luliconazole (Luzu) for full recommended time (2 weeks for athlete's foot, 1 week for jock itch and body ringworm). Don't stop early, even if you feel better, because the infection could come back and become harder to treat.

        • You might feel mild stinging, burning, or redness shortly after applying luliconazole (Luzu). These side effects should go away on their own, but speak to your prescriber if they become bothersome.

          • Let your prescriber know if your symptoms don't get better using luliconazole (Luzu) for the recommended time. You might need a different antifungal medication, or it might mean that your skin condition is due to something else.

            • If you’re breastfeeding, talk to your prescriber before using luliconazole (Luzu). It’s not known if this medication passes into breast milk, but it's not likely to cause harm. To be safe, avoid applying it to areas near the breast where your baby might come into contact with it.

              faqs

              Frequently asked questions about Luliconazole (Luzu)

              What's the difference between luliconazole (Luzu) and ketoconazole cream?
              Luliconazole (Luzu) and ketoconazole cream are both prescription antifungal creams, but they have some differences. For one, ketoconazole cream can also treat conditions like tinea versicolor (a fungal infection that causes discolored patches on the skin), seborrheic dermatitis, and certain skin yeast infections caused by Candida. Another difference is that luliconazole (Luzu) is used for 2 weeks to treat athlete's foot, while ketoconazole is used for 6 weeks. Talk to your healthcare professional to learn about other differences between these two medications.
              How long does it take for luliconazole (Luzu) to work?
              The length of time it takes for luliconazole (Luzu) to work can differ depending on the type of infection. In general, you should start to notice improvement in symptoms after a few days. Remember to use this medication for the recommended amount of time (2 weeks for athlete's foot, 1 week for jock itch and body ringworm), even if your symptoms are mostly gone. If you still have symptoms after the recommended treatment course, talk to your prescriber.
              Is luliconazole (Luzu) a steroid?
              No, luliconazole (Luzu) isn't a topical steroid. It's a topical antifungal used to treat certain fungal skin infections. Your healthcare professional (HCP) might also prescribe a steroid to help with redness and swelling. Don't use other medications together with luliconazole (Luzu) without checking with your HCP first.
              Can I use luliconazole (Luzu) on my face?
              Luliconazole (Luzu) isn't FDA-approved for treating fungal infections on the face, such as face ringworm (tinea faciei) or skin infections caused by Candida. Don't use it on your face unless your prescriber specifically tells you to since facial skin tends to be more sensitive and prone to unwanted side effects. Avoid getting the medication in your mouth or eyes.
              Is luliconazole (Luzu) over the counter?
              No, luliconazole (Luzu) isn't available over the counter. It requires a prescription from a healthcare professional.
              Is luliconazole (Luzu) safe to use during pregnancy?
              There isn't enough information to know if luliconazole (Luzu) is safe during pregnancy. Talk to your HCP about the risks and benefits of using this medication if you're pregnant.
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              What are the risks and warnings for Luliconazole (Luzu)?

              Luliconazole (Luzu) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

              risk-warning

              Use only on the skin

              Only use luliconazole (Luzu) on the skin. Avoid using it in the eyes, mouth, or vagina. If it gets into these areas, it might cause burning or other unwanted side effects. Rinse the medication out well with water if this happens.

              dosage

              Luliconazole (Luzu) dosage forms

              The average cost for 1 tube of 60g of 1% of Luliconazole (Luzu) is $97.05 with a free GoodRx coupon. This is 61.26% off the average retail price of $250.51.
              tube of cream
              Tube of cream
              DosageQuantityPrice as low asPrice per unit
              60g of 1%1 tube$97.05$97.05

              Typical dosing for Luliconazole (Luzu)

              Athlete's foot between the toes:

              • People 12 years and older: Apply a thin layer to the affected area and 1 inch around it once a day for 2 weeks.

              Jock itch and body ringworm:

              • People 2 years and older: Apply to the affected area and the surrounding skin once a day for 1 week.

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              How much does Luliconazole (Luzu) cost?

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              Luliconazole (Luzu) (generic)
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              alternatives

              What are alternatives to Luliconazole (Luzu)?

              There are a number of medications that your doctor can prescribe in place of Luliconazole (Luzu). Compare a few possible alternatives below.
              Luliconazole (Luzu)
              Used for:
              $97.05 Lowest GoodRx priceView Prices
              Ketoconazole cream
              Used for:
              $23.00 Lowest GoodRx priceView Prices
              Butenafine (Lotrimin Ultra)
              Used for:
              $9.31 Lowest GoodRx priceView Prices

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              References

              Best studies we found

              Bausch Health US, LLC. (2020). Luzu-lulconzaole cream [package insert]. DailyMed.

              Drugs and Lactation Database (LactMed®). (2021). Luliconazole. National Institute of Child Health and Human Development.

              Khanna, D., et al. (2014). Luliconazole for the treatment of fungal infections: An evidence-based review. Core Evidence.

              View All References (1)

              Pei, Y., et al. (2022). Tinea faciei. The Journal of Pediatrics.

              GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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