Jublia
Jublia (efinaconazole) is a prescription antifungal medication used to treat toenail fungus in people 6 years and older. It comes as a topical solution that you apply once a day directly to the affected toenail and the skin around it. Treatment usually lasts for almost a year. Common side effects include ingrown toenail and redness, itching, or irritation at the application site.
What is Jublia (efinaconazole)?
What is Jublia (efinaconazole) used for?
- Toenail fungus in people 6 years and older
How Jublia (efinaconazole) works
Jublia (efinaconazole) is an azole antifungal. It works by blocking the fungus from making its protective outer layer. Without this layer, the fungus can’t grow or survive.
Drug facts
More on Jublia (efinaconazole) essentials
Side effects of Jublia (efinaconazole)
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Ingrown toenail (2%)
- Skin irritation around the application site (2%)
- Blisters around the application site (2%)
Less Common Side Effects
- Pain around the application site
The following Jublia (efinaconazole) side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
- Ingrown nails
- Mild skin irritation, redness, or dryness
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Pros and cons of Jublia (efinaconazole)
Pros
- Used just once a day
- Applied directly to the toenail(s)
- Fewer side effects compared to oral antifungals
Cons
- Doesn't work as well as other antifungals
- Can be messy to apply
- Treatment lasts almost a year
Pharmacist tips for Jublia (efinaconazole)
- Apply Jublia (efinaconazole) to your toenail and the surrounding skin only. Don't take it by mouth, use it in your eyes, or place it inside the vagina.
- Use Jublia (efinaconazole) every day for 48 weeks (about 11 months). Don't stop early, even if your toenails look better, unless your prescriber tells you so. Stopping too soon can make the infection come back stronger.
- Avoid nail polish while using Jublia (efinaconazole). It's unclear whether it will cause this medication to not work as well. Wait until your infection is gone and your nails healed before applying nail polish again.
- Jublia (efinaconazole) can cause some redness, itching, and swelling at the application site. Let your prescriber know if these side effects don't go away.
- Store Jublia (efinaconazole) at room temperature in its original bottle. Keep it away from heat and open flames because the solution is flammable.
How to use Jublia (efinaconazole):
- Before using Jublia (efinaconazole), wash your feet and toes with soap and water and let them dry for at least 10 minutes.
- Use the brush applicator to apply Jublia (efinaconazole) to the affected toenail(s). Cover the whole nail, the cuticle, the skin around the nail, and the skin under the nail tip.
- Let Jublia (efinaconazole) dry fully before putting on socks or shoes. If you're treating your big toenail, apply a second coat shortly after.
- Wash your hands after using Jublia (efinaconazole). Even with the brush, it’s easy to touch the infected nail by accident and spread the fungus to other parts of your body or to other people.
More on Jublia (efinaconazole) tips
Common questions about Jublia
In studies, people started to see improvement within 3 months of using Jublia. But it can take up to a year to completely clear the infection. The reason why it takes so long is because the infected nail must grow out and be replaced by healthy nail. Because this process is slow, you need to use Jublia for 48 weeks.
No, Jublia doesn't cause liver damage. It's an azole antifungal, and this class of medications can sometimes cause liver problems when taken by mouth or given by injection. But since Jublia is applied directly to the nail, only a tiny amount of medication enters your body, so it doesn't harm the liver.
No, Jublia is only available by brand name only.
No, Jublia is available by prescription only by a healthcare professional.
It isn’t known if Jublia passes into breast milk. Since you only apply the solution to your toenail, very little of it gets into your body. This means the risk to your baby is likely very low. Still, you should talk with your prescriber before using Jublia while breastfeeding to make sure it’s safe for both of you.
It’s best to avoid nail polish or other cosmetic nail products while you’re using Jublia since it's not clear if it will impact how well the medication works. Ask your prescriber what nail care options are ok to use while you’re receiving treatment.
Jublia is only FDA approved to treat toenail fungus. It's usually not prescribed for fingernail fungus because it hasn't been well studied in people with this condition. One report suggests that it might help, but more research is needed. If you have a fungal infection on your fingernails, talk with your primary care provider about the best treatment.
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Jublia (efinaconazole) dosage
Bottle of topical solution| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 4ml of 10% | 1 bottle | $750.47 | $750.47 |
| 8ml of 10% | 1 bottle | $1,488.16 | $1,488.16 |
Typical dosage for Jublia (efinaconazole)
Apply to the affected toenail(s) once a day for 48 weeks (about 11 months) using the brush applicator. Make sure to apply enough of the solution to cover the entire toenail, the skin under it, and the skin around it.
How much does Jublia (efinaconazole) cost?
$750.47
What are alternatives to Jublia (efinaconazole)?
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