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Compare Loprox vs. Jublia

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Ciclopirox (Loprox, Penlac) and Jublia (efinaconazole) are both prescription antifungal medications, but they have some key differences. Ciclopirox is available in various forms, including cream, gel, shampoo, suspension, and nail lacquer, and can treat a wide range of fungal infections on the skin, nails, and scalp. In contrast, Jublia is only available as a topical solution specifically for treating toenail fungus. Ciclopirox has a generic version, making it a more affordable option, while Jublia is only available as a brand-name medication. Treatment duration also varies: ciclopirox nail lacquer can take up to a year to show results, similar to Jublia, which requires daily application for 11 months. Additionally, ciclopirox requires weekly removal of the nail lacquer with rubbing alcohol, whereas Jublia does not. Both medications should not be used with nail polish, but Jublia is flammable and should be kept away from open flames.

  • Ciclopirox
    jublia (efinaconazole)
  • Ciclopirox
    jublia (efinaconazole)

  • Summary of Loprox vs. Jublia

    Summary for Antifungal
    Prescription only

    Ciclopirox works well for various types of fungal skin and nail infections. It's available as a cream, gel, shampoo, suspension, and topical solution. Different formulations of ciclopirox can treat different medical conditions. This medication applied directly to the affected area(s), anywhere from twice daily to twice weekly, depending on what medical condition you have and what formulation of ciclopirox you're prescribed. It typically takes a week to a month before you notice improvements to your condition. But it can take 6 months or longer to see improvements for certain nail infections.

    Summary for Antifungal
    Prescription only

    Jublia (efinaconazole) is a prescription antifungal medication used to treat toenail fungus in people 6 years and older. It comes as a topical solution that you apply once a day directly to the affected toenail and the skin around it. Treatment usually lasts for almost a year. Common side effects include ingrown toenail and redness, itching, or irritation at the application site.

  • Indications of Loprox vs. Jublia

    Indications for
    •Jock itch
    •Athlete's foot
    •Ringworm
    •Tinea versicolor (fungal infection that causes discolored spots on the skin)
    •Yeast infections of the skin
    •Seborrheic dermatitis of the scalp - shampoo and gel only
    •Fungal nail infection - nail lacquer only
    Indications for
    •Toenail fungus in people 6 years and older

  • Pros and Cons of Loprox vs. Jublia

    Pros and Const for Antifungal
    Pros
    •Has few side effects
    •Safe to use if you have liver or kidney problems
    •Easy to use and can be applied right where you need it
    •Available as a topical suspension, gel, cream, shampoo, and nail lacquer
    •Available as a lower-cost generic
    Cons
    •Shouldn't be used on young children (age cut-off differs by formulaton)
    •Can take weeks or months to treat some infections
    •Requires a prescription
    •Not the best treatment option for severe or complicated fungal infections
    •Shampoo can irritate eyes and discolor hair
    Pros and Const for Antifungal
    Pros
    •Used just once a day
    •Applied directly to the toenail(s)
    •Fewer side effects compared to oral antifungals
    Cons
    •Doesn't work as well as other antifungals
    •Can be messy to apply
    •Treatment lasts almost a year

  • Common Side Effects of Loprox vs. Jublia

    Common Side Effects for
    •Mild skin redness (up to 46% with the nail lacquer)
    •Temporary burning or stinging (up to 34%, most common with the gel)
    •Itching
    Common Side Effects for
    •Ingrown toenail (2%)
    •Skin irritation around the application site (2%)
    •Blisters around the application site (2%)

  • Warnings of Loprox vs. Jublia

    Common Side Effects for
    •Only for use on the skin, nails, or scalp
    •Allergic reactions
    Common Side Effects for

  • Prices with our coupons for Loprox vs. Jublia

    Learn more about Ciclopirox
    Learn more about jublia

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