Key takeaways
Ciclopirox (Loprox, Penlac) and Jublia (efinaconazole) are both prescription antifungal medications, but they have some key differences. Ciclopirox is available in various forms, including cream, gel, shampoo, suspension, and nail lacquer, and can treat a wide range of fungal infections on the skin, nails, and scalp. In contrast, Jublia is only available as a topical solution specifically for treating toenail fungus. Ciclopirox has a generic version, making it a more affordable option, while Jublia is only available as a brand-name medication. Treatment duration also varies: ciclopirox nail lacquer can take up to a year to show results, similar to Jublia, which requires daily application for 11 months. Additionally, ciclopirox requires weekly removal of the nail lacquer with rubbing alcohol, whereas Jublia does not. Both medications should not be used with nail polish, but Jublia is flammable and should be kept away from open flames.
