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Compare Lamisil vs. Jublia

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Terbinafine (Lamisil) and Jublia (efinaconazole) are both antifungal medications used to treat nail fungus, but they have some key differences. Terbinafine is taken orally as a tablet, while Jublia is a topical solution applied directly to the toenail. Terbinafine is typically taken once a day for 6 to 12 weeks, whereas Jublia is applied daily for about 11 months. Terbinafine can cause side effects like headache, rash, and upset stomach, and it has a risk of serious liver damage. Jublia, on the other hand, mainly causes local side effects like ingrown toenails and skin irritation. Terbinafine is available as a lower-cost generic, but Jublia does not have a generic version. Additionally, Jublia is only approved for toenail fungus, while terbinafine can treat both fingernail and toenail infections.

  • Terbinafine
    jublia (efinaconazole)
  • Terbinafine
    jublia (efinaconazole)

  • Summary of Lamisil vs. Jublia

    Summary for Antifungal
    Prescription only

    Terbinafine is a first-choice treatment option for fingernail and toenail fungus. It's available as once-daily tablets, but treatment can take many weeks. Common side effects of terbinafine include headache, rash, diarrhea, and upset stomach. Terbinafine can have interactions with other medications, including certain antidepressants, beta-blockers, and some medications that treat an irregular heart rhythm.

    Summary for Antifungal
    Prescription only

    Jublia (efinaconazole) topical solution is an azole antifungal. It's applied directly to the toenail(s) once daily to treat toenail fungus. Treatment with Jublia (efinaconazole) typically lasts 11 months. Most people don't experience side effects from this medication, but some have reported ingrown toenail and application site reactions (e.g., irritation, pain). Jublia (efinaconazole) is prescription-only and there are no generic medications available.

  • Indications of Lamisil vs. Jublia

    Indications for
    •Fungal infection of toenail or fingernail
    Indications for
    •Fungal toenail infection in adults and children age 6 years and older

  • Pros and Cons of Lamisil vs. Jublia

    Pros and Const for Antifungal
    Pros
    •Works better to treat nail fungus than other treatment options
    •First-choice over other antifungal medications that are taken by mouth (e.g., versus itraconazole (Sporanox))
    •Only taken once a day, with or without food
    •Lower-cost generic available
    Cons
    •Can take several weeks to work
    •Can cause loss of taste or smell (sometimes permanently)
    •Not recommended if you have long-term or current liver problems
    •Not studied in children
    Pros and Const for Antifungal
    Pros
    •Possible option if over-the-counter antifungal medications didn't work well for you
    •Good choice for people who don't want to take pills, get surgery, or get laser treatment
    •Applied once daily
    Cons
    •Treatment lasts almost a year
    •Doesn't work as well as oral antifungals for treating more severe infections
    •It's not completely known how safe it is during pregnancy

  • Common Side Effects of Lamisil vs. Jublia

    Common Side Effects for
    •Headache (13%)
    •Rash (6%)
    •Diarrhea (6%)
    •Upset stomach (4%)
    Common Side Effects for
    •Ingrown toenail (2%)
    •Skin irritation around the application site (2%)
    •Blisters around the application site (2%)

  • Warnings of Lamisil vs. Jublia

    Common Side Effects for
    •Liver damage
    •Changes to taste and smell
    •Depression
    •Low white blood cell levels
    •Serious skin reactions
    •Lupus flare up
    •Clotting and bleeding problems
    Common Side Effects for
    •For use on toenails only
    •Flammable

  • Prices with our coupons for Lamisil vs. Jublia

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