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Compare Lamisil vs. Mycelex

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Terbinafine tablets and clotrimazole lozenges are both antifungal medications, but they treat different types of infections. Terbinafine is used to treat fungal infections of the fingernails and toenails and is taken as a once-daily tablet for several weeks. In contrast, clotrimazole (former brand name: Mycelex) is used to treat and prevent oral thrush and comes as a lozenge that you dissolve in your mouth multiple times a day. Terbinafine can cause side effects like headache, rash, and upset stomach, and it may interact with other medications. Clotrimazole has fewer side effects, mainly causing nausea and an unpleasant feeling in the mouth. Terbinafine is not recommended for people with liver problems, while clotrimazole lozenges should be used with caution in those with liver issues. Both medications require a prescription for oral forms, but both also have over-the-counter topical forms available.

  • Terbinafine
    Clotrimazole lozenge
  • Terbinafine
    Clotrimazole lozenge

  • Summary of Lamisil vs. Mycelex

    Summary for Antifungal
    Prescription only

    Terbinafine is a first-choice treatment option for fingernail and toenail fungus. It's available as once-daily tablets, but treatment can take many weeks. Common side effects of terbinafine include headache, rash, diarrhea, and upset stomach. Terbinafine can have interactions with other medications, including certain antidepressants, beta-blockers, and some medications that treat an irregular heart rhythm.

    Summary for Antifungal
    Prescription only

    Clotrimazole lozenge is an antifungal that treats and prevents yeast infection in the mouth and throat known as oral thrush. Clotrimazole lozenge is a troche, or a throat lozenge, that's slowly dissolved in the mouth, and it must be used several times a day. This medication is approved for use in people over the age of 3, but it should be used with caution in people with liver problems. Side effects can include nausea and an unpleasant feeling in the mouth. It isn't available over the counter, so you must have a prescription from your provider.

  • Indications of Lamisil vs. Mycelex

    Indications for
    •Fungal infection of toenail or fingernail
    Indications for
    •Treatment of oral thrush of the mouth and throat caused by Candida
    •Prevention of oral thrush for people undergoing chemotherapy, radiation, or steroid therapy for cancer or organ transplants

  • Pros and Cons of Lamisil vs. Mycelex

    Pros and Const for Antifungal
    Pros
    •Works better to treat nail fungus than other treatment options
    •First-choice over other antifungal medications that are taken by mouth (e.g., versus itraconazole (Sporanox))
    •Only taken once a day, with or without food
    •Lower-cost generic available
    Cons
    •Can take several weeks to work
    •Can cause loss of taste or smell (sometimes permanently)
    •Not recommended if you have long-term or current liver problems
    •Not studied in children
    Pros and Const for Antifungal
    Pros
    •Good at treating mild oral thrush
    •Very few side effects
    •Good option for people who have trouble swallowing pills
    Cons
    •Has to be taken multiple times a day
    •Takes about 30 minutes to fully dissolve in your mouth
    •Might cause changes to liver labs, which can suggest liver problems

  • Common Side Effects of Lamisil vs. Mycelex

    Common Side Effects for
    •Headache (13%)
    •Rash (6%)
    •Diarrhea (6%)
    •Upset stomach (4%)
    Common Side Effects for
    •Changes to liver lab test results (15%)

  • Warnings of Lamisil vs. Mycelex

    Common Side Effects for
    •Liver damage
    •Changes to taste and smell
    •Depression
    •Low white blood cell levels
    •Serious skin reactions
    •Lupus flare up
    •Clotting and bleeding problems
    Common Side Effects for
    •Liver problems

  • Prices with our coupons for Lamisil vs. Mycelex

    Learn more about Terbinafine
    Learn more about Clotrimazole lozenge

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