Ketoconazole cream and triamcinolone are both topical medications used to treat skin conditions, but they belong to different medication classes and have distinct uses. Ketoconazole cream is an antifungal medication used to treat fungal skin infections like ringworm, jock itch, athlete's foot, and seborrheic dermatitis. It works by damaging the protective outer layer of the fungus. Triamcinolone, on the other hand, is a corticosteroid used to treat inflammatory skin conditions such as eczema and psoriasis by reducing inflammation and irritation. While ketoconazole is applied once daily, triamcinolone is typically applied 2 to 4 times a day, depending on the formulation. Ketoconazole is available as a generic and requires a prescription, whereas triamcinolone is also prescription-only but comes in various forms like cream, ointment, lotion, and spray. Common side effects of ketoconazole include itching and skin irritation, while triamcinolone can cause burning, itching, and skin thinning if used excessively. Additionally, triamcinolone should not be used on infected skin, as it can worsen infections, whereas ketoconazole is specifically used to treat fungal infections.