Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Clobetasol (Clobex, Olux) and minoxidil (Loniten) are both prescription medications, but they belong to different classes and treat different conditions. Clobetasol is a topical corticosteroid used to treat skin conditions like psoriasis and eczema by reducing inflammation and immune response. Minoxidil, on the other hand, is an oral vasodilator used to treat high blood pressure by relaxing blood vessels. Clobetasol is applied to the skin in various forms like cream and shampoo, while minoxidil is taken by mouth. Clobetasol is available as a generic medication and is used for short-term treatment due to potential side effects like skin thinning. Minoxidil is also available as a generic and is typically used when other blood pressure medications haven't worked, but it can cause side effects like swelling and a fast heart rate. Clobetasol should not be used on the face or groin, and minoxidil requires additional medications to manage its side effects.
Clobetasol
Minoxidil
Clobetasol
Minoxidil
Summary of Clobetasol vs. Minoxidil
Summary for Corticosteroid
Prescription only
Clobetasol is a super potent (very strong) corticosteroid that's applied to the skin. It helps relieve skin inflammation and irritation from moderate-to-severe skin problems, like psoriasis. Clobetasol is available in many different formulations. This includes a cream, ointment, shampoo, topical solution, and foam. Most formulations are for people 12 years and older. But others, like the shampoo and lotion, are for adults only. Some side effects include burning, stinging, and irritation where it's applied. Clobetasol has both brand-name and generic options.
Summary for Vasodilator
Prescription only
Minoxidil helps treat high blood pressure (hypertension) in adults and children by relaxing the blood vessels. It's typically used only when you have extremely high blood pressure, when you have symptoms, and when other medications haven't worked to control your blood pressure. Minoxidil tablets are only for these situations because the medication has side effects and risks, like swelling of the body, fast heart rate, and other heart problems that can be potentially serious.
Indications of Clobetasol vs. Minoxidil
Indications for
•Skin rashes and itchy skin - all topical forms except shampoo
•Plaque psoriasis not on the scalp - all topical forms except shampoo
•Moderate-to-severe scalp psoriasis - shampoo and certain foams only