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Interleukin Antagonists

Interleukin antagonists are used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, crohn's disease, psoriasis and other autoinflammatory syndromes. They work to reduce swelling and to suppress the immune system.

Why are interleukin antagonists prescribed?

  1. Eczema (18%)
  2. Sinus Infection (17%)
  3. Asthma (17%)
  4. Nasal Polyps (17%)
  5. Eosinophilic Esophagitis (17%)
  6. Plaque Psoriasis (5%)
  7. Psoriatic Arthritis (3%)
  8. Crohn's Disease (2%)
  9. Ulcerative Colitis (2%)
  10. Rheumatoid Arthritis (2%)

Key takeaways

Interleukin antagonists are used to treat conditions such as rheumatoid arthritis, psoriasis, and asthma. They also have other uses, such as managing inflammatory bowel disease and COVID-19. These medications work by blocking the action of specific interleukins, which are proteins that can cause inflammation and other immune responses in your body. Interleukin antagonists typically come as injections and infusions. There are many examples available, including Stelara (ustekinumab), Bimzelx (bimekizumab), Nucala (mepolizumab), and more.

Prices for popular Interleukin Antagonists medications
Viewing 25 of 38 medications
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Bimzelx

as low as$5
BIMEKIZUMAB treats psoriasis. It works by slowing down an overactive immune system.  It is a monoclonal antibody.
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Dupixent

as low as$0
Dupixent (dupilumab) is used to treat certain patients with eczema, prurigo nodularis (PN), chronic spontaneous urticaria (CSU), bullous pemphigoid (BP), asthma, chronic obstructive pulmonary disease (COPD), nasal polyps (NP) and eosinophilic esophagitis (EOE). There is currently no generic alternative to Dupixent. It may be covered by your Medicare or insurance plan.
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Ebglyss

as low as$5
Ebglyss is part of the Interleukin Antagonists class and treats Eczema. Interleukin antagonists are used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, crohn's disease, psoriasis and other autoinflammatory syndromes. They work to reduce swelling and to suppress the immune system. Ebglyss is only available as a brand name drug.
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Starjemza

as low as$513
Starjemza is part of the Interleukin Antagonists class and treats Plaque Psoriasis, Psoriatic Arthritis, Ulcerative Colitis and other conditions. Interleukin antagonists are used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, crohn's disease, psoriasis and other autoinflammatory syndromes. They work to reduce swelling and to suppress the immune system. Starjemza is only available as a brand name drug.
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Actemra

as low as$571
TOCILIZUMAB treats autoimmune conditions, such as arthritis. It works by slowing down an overactive immune system. It may also be used to treat severe COVID-19 in people who are hospitalized. It is a monoclonal antibody.
Yesintek is part of the Interleukin Antagonists class and treats Plaque Psoriasis, Psoriatic Arthritis, Ulcerative Colitis and other conditions. Interleukin antagonists are used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, crohn's disease, psoriasis and other autoinflammatory syndromes. They work to reduce swelling and to suppress the immune system. Yesintek is only available as a brand name drug.
Pyzchiva is part of the Interleukin Antagonists class and treats Plaque Psoriasis, Psoriatic Arthritis, Ulcerative Colitis and other conditions. Interleukin antagonists are used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, crohn's disease, psoriasis and other autoinflammatory syndromes. They work to reduce swelling and to suppress the immune system. Pyzchiva is only available as a brand name drug.
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Wezlana

as low as$2,816
Wezlana is part of the Interleukin Antagonists class and treats Psoriasis, Psoriatic Arthritis, Ulcerative Colitis and other conditions. Interleukin antagonists are used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, crohn's disease, psoriasis and other autoinflammatory syndromes. They work to reduce swelling and to suppress the immune system. Wezlana is only available as a brand name drug.
Ustekinumab-aekn (Selarsdi) is part of the Interleukin Antagonists class and treats Plaque Psoriasis, Psoriatic Arthritis, Ulcerative Colitis and other conditions. Interleukin antagonists are used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, crohn's disease, psoriasis and other autoinflammatory syndromes. They work to reduce swelling and to suppress the immune system. Ustekinumab-aekn (Selarsdi) is only available as a brand name drug.
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Nucala

as low as$4,235
Nucala (mepolizumab) is used in combination with other treatments to help treat severe asthma. It is also used for the treatment of hypereosinophilic syndrome, rhinosinusitis with nasal polyps, and a rare form of vasculitis. Nucala is an Interleukin Antagonist, which works by reducing inflammation in the lungs. The most common form of Nucala is a 100mg/ml autoinjector. It is also available as a 100mg/ml syringe, 40mg/0.4ml syringe, and 100mg vial. There are currently no generic alternatives for Nucala. It may be covered by some Medicare and insurance plans.
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Adbry

as low as$4,296
TRALOKINUMAB reduces swelling, redness, itching, or rashes caused by skin conditions, such as eczema. It works by decreasing inflammation of the skin. It is a monoclonal antibody.
Nemluvio is part of the Interleukin Antagonists class and treats Prurigo Nodularis and Eczema. Interleukin antagonists are used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, crohn's disease, psoriasis and other autoinflammatory syndromes. They work to reduce swelling and to suppress the immune system. Nemluvio is only available as a brand name drug.
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Siliq

as low as$4,665
BRODALUMAB treats psoriasis. It works by slowing down an overactive immune system. It is a monoclonal antibody.
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Kineret

as low as$6,693
ANAKINRA treats rheumatoid arthritis and other inflammatory conditions, such as neonatal-onset multisystem inflammatory disease (NOMID) and deficiency of interleukin-1 receptor antagonist (DIRA). It works by slowing down an overactive immune system.
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Taltz

as low as$8,083
Taltz (ixekizumab) is used to treat adults with psoriatic arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis, and for adults and children with moderate to severe plaque psoriasis. There are no generic alternatives to Taltz. It may be covered by Medicare or insurance plans.
SECUKINUMAB treats autoimmune conditions, such as psoriasis and arthritis. It works by slowing down an overactive immune system. It is a monoclonal antibody.
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Icotyde

as low as$8,360
Icotyde is part of the Interleukin Antagonists class and treats Plaque Psoriasis. Interleukin antagonists are used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, crohn's disease, psoriasis and other autoinflammatory syndromes. They work to reduce swelling and to suppress the immune system. Icotyde is only available as a brand name drug.
Stelara (ustekinumab) is an expensive drug used to treat plaque psoriasis, psoriatic arthritis and ulcerative colitis. This medicine is also used to treat Crohn's disease. It is not a cure. This drug is more popular than comparable drugs. There are currently no generic alternatives to Stelara. While 96% of insurance plans cover the most common version of Stelara at a co-pay of $32.50-$80.00, many of them have restrictions.
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Omvoh

as low as$11,523
MIRIKIZUMAB treats ulcerative colitis. It works by decreasing inflammation in the digestive tract. It is a monoclonal antibody.
Tremfya (guselkumab) is indicated for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy. It is also used for the treatment of adults with active psoriatic arthritis. There are currently no generic alternatives for Tremfya. It may be covered by your Medicare or insurance plan, but some pharmacy coupons or cash prices could help offset the cost.
SATRALIZUMAB treats neuromyelitis optica spectrum disorder (NMOSD), a condition that causes inflammation in the nerves of the eyes and spinal cord. It works by decreasing inflammation. It is a monoclonal antibody.
SPESOLIMAB treats generalized pustular psoriasis (GPP) flares. It works by slowing down an overactive immune system. It is a monoclonal antibody.
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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