Skip to main content

Anti-epileptics

Anti-epileptics are used to control seizures to treat epilepsy and trigeminal neuralgia. They work by reducing irregular impulses in the brain that cause seizures and pain.

Why are anti epileptics prescribed?

  1. Epilepsy (53%)
  2. Postherpetic Neuralgia (29%)
  3. Bipolar Disorder (5%)
  4. Lennox-Gastaut Syndrome (4%)
  5. Diabetic Neuropathy (3%)
  6. Fibromyalgia (3%)
  7. Migraine (3%)
  8. Trigeminal Neuralgia (1%)
  9. Restless Leg Syndrome (0%)
  10. Neonatal Seizures (0%)

Key takeaways

Anti-epileptics are used to prevent and control seizures. Some also have other uses, such as managing nerve pain, migraines, and fibromyalgia. These medications work by stabilizing electrical activity in your brain. Anti-epileptics come in different forms, including oral pills and extended-release tablets. Examples include gabapentin (Gralise, Neurontin), lamotrigine (Lamictal), levetiracetam (Keppra, Roweepra, Keppra XR, Roweepra XR), pregabalin (Lyrica), topiramate (Topamax), and zonisamide (Zonegran).

Prices for popular Anti-epileptics medications
Viewing 25 of 48 medications
tablet icon

Gralise (gabapentin)

as low as$11
Gralise (gabapentin) is used to treat pain after shingles, or postherpetic neuralgia (PHN). It is available as a brand and generic.

GoodRx has partnered with InsideRx and Almatica Pharma to reduce the price for this prescription. Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Gralise is covered by some Medicare and insurance plans.
See pricesMore info
capsule icon

Neurontin (gabapentin)

as low as$11
Gabapentin (Neurontin) is an inexpensive drug used to control partial seizures in adults with epilepsy. It is also used to treat certain types of nerve pain. This drug is more popular than comparable drugs. It is available in generic and brand versions. Generic gabapentin is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
tablet icon

Lamictal (lamotrigine)

as low as$7
Lamotrigine (Lamictal) is an inexpensive drug used to control seizures in adults and children with epilepsy and Lennox-Gastaut syndrome. This drug is slightly more popular than comparable drugs. It is available in brand and generic versions. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
tablet icon

Keppra (levetiracetam)

as low as$9
Levetiracetam (Keppra, Roweepra) is a moderately priced drug used with other medications to treat certain types of seizures. This drug is slightly less popular than comparable drugs. It is available in brand and generic versions. Generic levetiracetam is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
tablet icon

Roweepra (levetiracetam)

as low as$9
Levetiracetam (Keppra, Roweepra) is a moderately priced drug used with other medications to treat certain types of seizures. This drug is slightly less popular than comparable drugs. It is available in brand and generic versions. Generic levetiracetam is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
capsule icon

Lyrica (pregabalin)

as low as$13
Lyrica (pregabalin) is used to control seizures and treat nerve pain from diabetes, shingles, spinal cord injury, and fibromyalgia. It is slightly more popular than other anti-epileptics. It is available in brand and generic versions.

GoodRx has partnered with InsideRx and Pfizer to reduce the price for this prescription. Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Lyrica is covered by most Medicare and insurance plans.
See pricesMore info
tablet icon

Keppra XR (levetiracetam ER)

as low as$35
Levetiracetam ER (Keppra XR) is an expensive drug used with other medicines to treat certain types of seizures. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic levetiracetam ER is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
tablet icon

Roweepra XR (levetiracetam ER)

as low as$35
LEVETIRACETAM prevents and controls seizures in people with epilepsy. It works by calming overactive nerves in your body.
See pricesMore info
tablet icon

Topamax (topiramate)

as low as$8
Topiramate (Topamax) is an inexpensive drug used to treat seizures in adults or children with epilepsy. It is also used for the prevention of migraine headaches. It is slightly more popular than comparable drugs. It is available in brand and generic versions. Generic topiramate is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
tablet icon

Subvenite

as low as$9
LAMOTRIGINE prevents and controls seizures in people with epilepsy. It may also be used to treat bipolar disorder. It works by calming overactive nerves in your body.
See pricesMore info
tablet icon

Depakote (divalproex)

as low as$11
Divalproex (Depakote) is a moderately priced drug used to prevent seizures caused by some forms of epilepsy. It is also used to treat bipolar mania and to prevent migraine headaches. This drug is slightly less popular than other comparable drugs. It is available in brand and generic versions. Generic divalproex is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
capsule icon

Dilantin (phenytoin)

as low as$12
Phenytoin (Dilantin, Phenytek) is a moderately priced drug used to control seizures in certain types of epilepsy. It is also used to prevent seizures during or after surgery. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic phenytoin is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
capsule icon

Phenytek (phenytoin)

as low as$12
Phenytoin (Dilantin, Phenytek) is a moderately priced drug used to control seizures in certain types of epilepsy. It is also used to prevent seizures during or after surgery. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic phenytoin is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
tablet icon

Mysoline (primidone)

as low as$15
Primidone (Mysoline) is a moderately priced drug used to control seizures in certain types of epilepsy. It is not for use in absence (petit mal) seizures. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic primidone is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
tablet icon

Depakote ER (divalproex ER)

as low as$19
Divalproex ER (Depakote ER) is an expensive drug used to prevent seizures caused by some forms of epilepsy. It is also used to treat bipolar mania and to prevent migraine headaches. This drug is slightly less popular than other comparable drugs. It is available in brand and generic versions. Generic divalproex er is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
tablet icon

Trileptal (oxcarbazepine)

as low as$19
Oxcarbazepine (Trileptal) is a moderately priced drug used to treat people with epilepsy. It helps prevent partial seizures. This drug is less popular than other comparable drugs. It is available in brand and generic versions. The most common version of Trileptal is covered by 76% of insurance plans at a co-pay of $60.00-$80.00, however, some pharmacy coupons or cash prices may be lower.
See pricesMore info
capsule icon

Zonegran (zonisamide)

as low as$19
Zonisamide (Zonegran) is a moderately priced drug used to control partial seizures in adults with epilepsy. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic zonisamide is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
capsule icon

valproic acid

as low as$24
Valproic acid (Depakene) is a moderately priced drug used to treat certain types of seizures in patients with epilepsy. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic valproic acid is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
tablet icon

Vimpat (lacosamide)

as low as$26
Lacosamide (Vimpat) is used to control seizures caused by certain types of epilepsy. A generic version of Vimpat may become available in 2022.
See pricesMore info
tablet icon

Tegretol (carbamazepine, epitol)

as low as$30
Carbamazepine (Tegretol, epitol) is a moderately priced drug used to control seizures caused by certain types of epilepsy. This medicine is also used to treat nerve related pain. This drug is less popular than comparable drugs. It is available in multiple brand and generic versions. Generic carbamazepine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
tablet icon

Lamictal XR (lamotrigine ER)

as low as$31
Lamotrigine ER (Lamictal XR) is an expensive drug used to control seizures in adults and children with epilepsy. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic lamotrigine ER is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
capsule icon

Carbatrol (carbamazepine ER)

as low as$32
CARBAMAZEPINE prevents and controls seizures in people with epilepsy. It may also be used to treat nerve pain. It works by calming overactive nerves in your body.
See pricesMore info
tablet icon

Tegretol XR (carbamazepine ER)

as low as$32
Carbamazepine ER (Tegretol XR) is a moderately priced drug used to control seizures caused by certain types of epilepsy. This medicine is also used to treat nerve related pain. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic carbamazepine ER is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
capsule icon

Celontin (methsuximide)

as low as$43
Methsuximide (Celontin) is a moderately priced drug used to control seizures in certain types of epilepsy. This drug is less popular than comparable drugs. It is available as a brand and generic. It is currently covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
capsule icon

Qudexy XR (topiramate ER)

as low as$44
Topiramate ER (Qudexy XR) is an expensive drug used to treat epilepsy and Lennox Gastaut syndrome. This drug is less popular than comparable drugs. It is available in generic and brand versions. It is covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

Subscribe and save

Get prescription saving tips and more from GoodRx Health. Enter your email to sign up

By signing up, I agree to GoodRx’s Terms of Use and Privacy Policy, and to receive marketing messages from GoodRx.

Latest Articles

mother with toddler looking serious-1267558400

10 Common Antiepileptic Seizure Medications to Know

Kevin Le, PharmD, BCPS, BCPPSUpdated on Apr 2, 2025
Health: Pain: GettyImages-1322012192

Should You Take Gabapentin for Back Pain? Experts Discuss

Kelly Elterman, MDUpdated on Mar 26, 2025
Anti-epileptics: medical consulation 1352346247

Briviact vs. Keppra for Epilepsy: 6 Differences to Consider

Patricia Weiser, PharmDPublished on Mar 3, 2025
oxcarbazepine: side effect oxcarbazepine

8 Oxcarbazepine Side Effects to Know About: Dizziness, Tiredness, and More

Alex Brewer, PharmD, MBAPublished on Jan 2, 2025
oxcarbazepine: drug interaction oxcarbazepine

Alcohol, Birth Control Pills, and More: 8 Oxcarbazepine Interactions to Watch Out For

Alex Brewer, PharmD, MBAPublished on Dec 17, 2024
benzodiazepines: drug interaction benzodiazepine

Alcohol, Opioids, and Gabapentin: 10 Benzodiazepine Interactions to Watch For

Austin Ulrich, PharmD, BCACPPublished on Dec 4, 2024
Health: Hypertension: GettyImages dv1051014

Does Gabapentin Cause Weight Gain? Here’s What You Need to Know

Alex Brewer, PharmD, MBAUpdated on Nov 5, 2024
benzodiazepines: man taking oral medication 1138124057

What Are Benzodiazepines? 10 Things to Know About This Group Of Medications

Daphne Berryhill, RPhPublished on Oct 3, 2024
Liver: Side effect: kidney pain bathroom sink mirror 607488402

14 Medications That May Elevate Liver Enzymes and Raise Your Risk of Liver Damage

Rachel Feaster, PharmD, BCOP, BCPSUpdated on Sep 23, 2024
Health: Gabapentin: pharmacist consultation with patient 1179644947

How Does Gabapentin Work? 6 FAQs Answered

Rosanna Sutherby, PharmDUpdated on Sep 18, 2024
clonazepam: man taking medication at home 1475394041

How Does Clonazepam Work? All About Its Mechanism of Action

Alex Brewer, PharmD, MBAPublished on Sep 11, 2024
briviact: briviact dosage

Briviact Dosages: Your GoodRx Guide

Alex Evans, PharmD, MBAPublished on Aug 20, 2024
Diabetic Neuropathy: How It Affects Your Feet
Video play button

Diabetes and Foot Pain: How to Prevent and Treat Diabetic Neuropathy

2:00
Updated on Aug 16, 2024
Health: pain: woman reading medication label-1254588010

Sciatic Nerve Pain: 6 Prescription Medications That May Help

Christina Aungst, PharmDUpdated on Aug 2, 2024
Trileptal: man with pill and water 1372814954

Does Trileptal Cause Sexual Side Effects?

Alex Evans, PharmD, MBAPublished on Jul 29, 2024
Serious Complications of Shingles and How to Avoid Them
Video play button

How to Treat Shingles: Medication, Pain Relief, Home Remedies and More

2:10
Updated on Jul 9, 2024
Lamotrigine: side effects lamotrigine

Does Lamotrigine Cause Sexual Side Effects?

Joshua Murdock, PharmD, BCBBSPublished on Jul 9, 2024
Gabapentin: drug interaction gabapentin

5 Gabapentin Interactions You Should Know About

Austin Ulrich, PharmD, BCACPUpdated on Jul 2, 2024
phenytoin: drug interaction phenytoin

11 Phenytoin Interactions You Should Know About

Makaela Premont, PharmDUpdated on Jun 11, 2024
cat licking paw-1212822618

7 Common Reasons Cats Lick Themselves — and When It Becomes a Problem

Ana GasconUpdated on May 28, 2024
Medication education: hcp senior patient going through medications 182789562

10 Medications That Are Dangerous to Stop Abruptly

Vanessa Carranza, PharmDUpdated on May 14, 2024
Topiramate: side effects topiramate

11 Topiramate Side Effects You Should Know About

Amy B. Gragnolati, PharmD, BCPSUpdated on May 2, 2024
gaba-agonists: man researching medication on smartphone 1473378723

What is GABA? 6 Things to Know About This Calming Chemical Messenger

Patricia Weiser, PharmDPublished on Apr 18, 2024
depakote: side effects depakote

12 Depakote Side Effects You Should Know About

Amy B. Gragnolati, PharmD, BCPSUpdated on Apr 1, 2024

Browse medications

View All
Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.
ABCDEFGHIJKLMNOPQRSTUVWXYZ