Compare Neurontin vs. Chlorpromazine

Gabapentin (Neurontin) and Chlorpromazine (Thorazine) are both prescription medications, but they serve different purposes and belong to different drug classes. Gabapentin is an antiepileptic used to treat certain seizures and nerve pain, while Chlorpromazine is a first-generation antipsychotic used for a variety of conditions, including psychotic disorders, schizophrenia, and severe behavioral issues in children. Gabapentin is typically taken three times a day and is available in generic form as pills and a liquid. In contrast, Chlorpromazine can be taken two to four times a day and is available as a tablet and injection, but the brand Thorazine is no longer available. Gabapentin works by affecting nerve activation, whereas Chlorpromazine controls dopamine activity in the brain. Common side effects of Gabapentin include dizziness and sleepiness, while Chlorpromazine can cause drowsiness, uncontrollable muscle movements, and dry mouth. Both medications can cause withdrawal symptoms if stopped suddenly, but Chlorpromazine also carries a higher risk of death in older adults with dementia-related psychosis.