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Neurontin vs. Paxil

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Gabapentin (Neurontin) and Paroxetine (Paxil) are both prescription medications, but they are used for different conditions and belong to different drug classes. Gabapentin is an antiepileptic medication used to treat certain seizures and nerve pain, while Paroxetine is a selective serotonin reuptake inhibitor (SSRI) used for various mental health conditions like depression, anxiety, and PTSD. Gabapentin is typically taken three times a day and is available in both generic and brand forms, including immediate-release and extended-release versions. In contrast, Paroxetine is usually taken once daily and is available as both immediate-release and extended-release tablets, as well as an oral suspension. Common side effects of Gabapentin include dizziness and sleepiness, whereas Paroxetine can cause nausea, sexual side effects, and weight gain. Additionally, Gabapentin can be misused and is controlled in some states, while Paroxetine is not a controlled substance. Both medications can cause withdrawal symptoms if stopped abruptly, but they work in different ways: Gabapentin affects nerve activity, while Paroxetine increases serotonin levels in the brain.

Gabapentin

(Neurontin)

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Paroxetine

(Paxil)

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Summary for Neurontin

Prescription only

Gabapentin, also known by its brand name Neurontin, is used to treat nerve pain from shingles in adults. This medication can also help treat partial (focal) seizures in adults and children. Gabapentin (Neurontin) comes as pills and a liquid that you take by mouth. The dosage depends on things like what you're treating, how old you are, and how well the medication is working. In general, you take it 3 times a day. Common side effects include making you feel dizzy and sleepy.

Indications for Neurontin

Pros and Cons for Neurontin

Pros

  • An option for relieving nerve pain caused by shingles
  • Can take with other anti-seizure medications for partial-onset seizures in people 3 years and older
  • Available as a tablet, capsule, and liquid for those who have trouble swallowing pills

Cons

  • Usually need to taken three times per day
  • Can cause dizziness and sleepiness
  • Can cause withdrawal symptoms if you stop taking the medication too suddenly or too fast

Common Side Effects for Neurontin

  • Sleepiness (19%)
  • Dizziness (17%)
  • Poor muscle control or clumsiness (13%)
  • Fatigue (11%)

Warnings for Neurontin

  • Severe allergic reactions
  • Sleepiness, dizziness, and trouble concentrating
  • Risk of suicidal thoughts and behavior
  • Higher risk of seizures and other side effects if you stop the medication too suddenly or too fast
  • Dangerously slowed breathing
  • Changes in behavior in children

Summary for Paxil

Prescription only

Paroxetine (also known by it's brand name Paxil) is a selective serotonin reuptake inhibitor (SSRI), used for different types of anxiety problems and depression. It's available as a brand name and generic version, and it comes as an immediate-release tablet, an oral suspension, and an extended-release tablet. Possible side effects include nausea, sexual side effects, and weight gain. It can also cause withdrawal symptoms (e.g., headache, trouble sleeping, anxiety) if you suddenly stop taking it.

Indications for Paxil

Pros and Cons for Paxil

Pros

  • Only needs to be taken once daily
  • Available as a tablet and oral liquid
  • Can be taken with or without food
  • Can be used for many different mental health conditions
  • Can be helpful for people who have both anxiety and depression

Cons

Common Side Effects for Paxil

  • Abnormal ejaculation (up to 28%)
  • Nausea (up to 25%)
  • Weakness (up to 22%)
  • Sleepiness or trouble sleeping (up to 24%)
  • Dry mouth (up to 18%)
  • Constipation (up to 16%)
  • Sweating (up to 14%)
  • Dizziness (up to 14%)
  • Diarrhea (up to 12%)
  • Low libido (up to 12%)
  • Shakiness (up to 11%)

Warnings for Paxil

  • Worsening depression, suicidal thoughts, and unusual behavior
  • Serotonin syndrome
  • Risk of harm to unborn babies
  • Sexual problems
  • Withdrawal
  • Risk of bleeding
  • Not for use alone in bipolar disorder
  • Glaucoma
  • Low blood sodium levels
  • Seizures
  • Risk of abnormal heart rhythm from interactions

Prices with our coupons for Neurontin vs. Paxil

Price Card Drug Icon
Gabapentin60 capsules / 300mg
$10.29$111.22
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Paroxetine30 tablets / 20mg
$4.00$4.00
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