Key takeaways
Lamotrigine (Lamictal) and gabapentin (Neurontin) are both antiepileptic medications, but they have different uses and side effects. Lamotrigine is used to treat seizures and bipolar disorder, while gabapentin is used for seizures and nerve pain from shingles. Lamotrigine is available in both immediate-release and extended-release forms, whereas gabapentin is typically taken three times a day in immediate-release form. Gabapentin can cause dizziness and sleepiness, and it has a risk of misuse, leading some states to classify it as a controlled substance. Lamotrigine, on the other hand, can cause serious skin reactions and requires a slow increase in dosage to minimize this risk. Both medications can increase the risk of suicidal thoughts and should not be stopped suddenly without consulting a healthcare provider. Lamotrigine is available as a lower-cost generic, while gabapentin is also available in generic form and as a liquid for those who have trouble swallowing pills.
