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Compare Vraylar vs. Lamictal

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Vraylar (cariprazine)
    Lamotrigine (Lamictal)
  • Vraylar (cariprazine)
    Lamotrigine (Lamictal)

  • Summary of Vraylar vs. Lamictal

    Summary for Atypical antipsychotic
    Prescription only

    Vraylar (cariprazine) is an atypical antipsychotic used to treat schizophrenia and bipolar I disorder in adults. It can also be used as an add-on medication to help with major depressive disorder (MDD). Vraylar (cariprazine) is taken by mouth once a day. Some common side effects of this medication include uncontrolled muscle movements, headache, and restlessness. Unlike some other antipsychotic medications, Vraylar (cariprazine) causes minimal weight gain. Vraylar (cariprazine) is brand name only and not available as a generic medication.

    Summary for Antiepileptic
    Prescription only

    Lamotrigine (Lamictal) can be used alone or together with other medications to treat seizures. It's available in immediate-release and extended-release formulations. The immediate-release formulation can also be used for bipolar disorder. Lamotrigine (Lamictal) can cause serious skin reactions like rash.

  • Indications of Vraylar vs. Lamictal

    Indications for
    •Schizophrenia
    •Manic or mixed episodes of bipolar I disorder
    •Bipolar depression of bipolar I disorder
    •Major depressive disorder (MDD), as an add-on medication
    Indications for
    •Seizures (partial seizures, tonic-clonic seizures)
    •Seizures of Lennox-Gastaut syndrome - immediate-release only
    •Bipolar disorder - immediate-release only

  • Pros and Cons of Vraylar vs. Lamictal

    Pros and Const for Atypical antipsychotic
    Pros
    •Taken once a day
    •Can be taken with or without food
    •Works in your body for a longer period of time than other similar medications
    Cons
    •You might have to see your healthcare provider several times until you find a dose that works best for you.
    •Higher risk for uncontrolled muscle movements than some similar medications
    •Might take several weeks before you experience the full effects of this medication
    Pros and Const for Antiepileptic
    Pros
    •Starter kits are available to help with dosing when you first start the medication.
    •Dose can be adjusted based on your response
    •Available in various forms: chewable tablets, quick-dissolving tablets, and extended-release tablets
    •Available as a lower-cost generic
    Cons
    •Can cause dizziness
    •Dose has to be slowly raised due to risk of serious rash
    •Interacts with many medications such as birth control pills, divalproex (Depakote), and dofetilide (Tikosyn)
    •Unknown if safe or works well in children under 2 years old (immediate release) or children under 13 years old (extended release)

  • Common Side Effects of Vraylar vs. Lamictal

    Common Side Effects for
    •Uncontrolled muscle movements (up to 20%)
    •Headache (up to 18%)
    •Restlessness (up to 14%)
    •Trouble sleeping (up to 13%)
    •Constipation (up to 10%)
    •Nausea (up to 8%)
    •Stomach pain (up to 7%)
    •Toothache (up to 6%)
    Common Side Effects for

    Below are common side effects reported by adults who took this medication along with other treatments. Percentages can differ depending on your condition (e.g., bipolar) and your age.

    Immediate release

    •Dizziness (38%)
    •Headache (29%)
    •Double vision (28%)
    •Loss of coordination (22%)
    •Nausea (19%)
    •Blurry vision (16%)
    •Sleepiness (14%)
    •Stuffy nose (14%)
    •Sore throat (10%)
    •Rash (10%)

    Extended release

    •Dizziness (14%)
    •Nausea (7%)
    •Vomiting (6%)
    •Tremor (6%)
    •Feeling tired (6%)
    •Double vision (5%)
    •Diarrhea (5%)

  • Warnings of Vraylar vs. Lamictal

    Common Side Effects for
    •Higher risk of death in older adults with dementia-related psychosis
    •Suicidal thoughts and behavior
    •Neuroleptic malignant syndrome
    •High blood sugar, high cholesterol, and weight gain
    •Difficulty controlling movements (tardive dyskinesia)
    •Higher risk of infections
    •Higher risk of falls
    •Trouble controlling body temperature
    •Difficulty swallowing
    •Seizures
    Common Side Effects for
    •Severe skin reactions and allergic reactions
    •Overactive immune system
    •Irregular heartbeat
    •Suicidal behavior and thoughts
    •Meningitis (brain inflammation)
    •Withdrawal seizures
    •Possible eye problems
    •Interaction with other medications

  • Prices with our coupons for Vraylar vs. Lamictal

    Learn more about Vraylar
    Learn more about Lamotrigine

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