Sustol
(granisetron)
Get free couponsOlanzapine
(Zyprexa)
Get free couponsSummary for Sustol
Sustol (granisetron) is a medication used to prevent nausea and vomiting due to cancer medications (chemotherapy) in adults. It can last for up to 7 days.
Indications for Sustol
- Prevention of nausea and vomiting caused by chemotherapy
Pros and Cons for Sustol
Pros
- Works well for preventing nausea
- Lasts for up to 7 days
- Good option for people who have a hard time taking pills
Cons
- Must be given by a healthcare provider as an injection under the skin
- Not clear how safe the medication is in pregnant or breastfeeding females
- Can't be used in children
Common Side Effects for Sustol
- Injection site reactions, such as bruising, redness, or swelling (37-62%)
- Constipation (14-22%)
- Weakness or lack of energy (11-21%)
- Headache (9-13%)
- Diarrhea (8-9%)
- Stomach pain (7%)
Warnings for Sustol
- Injection site reactions
- Serotonin syndrome
- Severe allergic reactions
- Stomach problems
Summary for Zyprexa
Olanzapine (Zyprexa) is an atypical antipsychotic used treat schizophrenia or bipolar disorder. It can also treat depression, in combination with fluoxetine (Prozac), when other treatments haven't worked well. This medication is thought to work by balancing the levels of certain chemicals in the brain. Olanzapine (Zyprexa) is taken by mouth, typically once daily, by adults and children. Olanzapine (Zyprexa) is also available as an injection that's usually given in a hospital or clinic setting. Some of the more common side effects of olanzapine (Zyprexa) include sleep problems, dizziness, and weight gain.
Indications for Zyprexa
- Schizophrenia in adults and children age 13 years and older
- Bipolar I disorder in adults and children age 13 years and older
When taken with fluoxetine (Prozac):
- Bipolar depression in adults and children age 10 years and older
- Depression that hasn't responded well to other treatments
Pros and Cons for Zyprexa
Pros
- Taken by mouth
- Taken once daily
- Might notice an improvement in your symptoms in as early as a week of starting olanzapine (Zyprexa)
- Available as a lower-cost generic
Cons
- Can cause anticholinergic side effects, such as constipation and dry mouth
- Can affect your sleep
- More likely to cause weight gain, high blood cholesterol, and high blood sugar levels compared to some other atypical antipsychotics
Common Side Effects for Zyprexa
- Sleepiness (29%)
- Trouble sleeping (12%)
- Accidental injury (12%)
- Dizziness (11%)
- Weakness (10%)
- Dry mouth (9%)
- Constipation (9%)
- Upset stomach (7%)
- Runny nose (7%)
Warnings for Zyprexa
- Higher risk of death in older people with dementia-related psychosis
- Worsening depression, suicidal thoughts and behavior
- Severe allergic skin reactions
- Neuroleptic malignant syndrome
- Weight gain, higher blood sugar, and higher cholesterol levels
- Difficulty controlling body movements
- Changes in blood pressure and higher risk of falls
- Risk of infection (from low white blood cell count)
- Seizures
- High prolactin levels
- Difficulty concentrating and extreme sleepiness
- Anticholinergic side effects
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