Sustol vs. Zyprexa for Bipolar Disorder: Important Differences and Potential Risks.

Sustol

(granisetron)

Olanzapine

(Zyprexa)

Summary for Sustol

Prescription only

Sustol (granisetron) is a medication used to prevent nausea and vomiting due to cancer medications (chemotherapy) in adults. It can last for up to 7 days.

Indications for Sustol

Prevention of nausea and vomiting caused by chemotherapy

Pros and Cons for Sustol

Pros

Works well for preventing nausea
Lasts for up to 7 days
Good option for people who have a hard time taking pills

Cons

Must be given by a healthcare provider as an injection under the skin
Not clear how safe the medication is in pregnant or breastfeeding females
Can't be used in children

Common Side Effects for Sustol

Injection site reactions, such as bruising, redness, or swelling (37-62%)
Constipation (14-22%)
Weakness or lack of energy (11-21%)
Headache (9-13%)
Diarrhea (8-9%)
Stomach pain (7%)

Warnings for Sustol

Injection site reactions
Serotonin syndrome
Severe allergic reactions
Stomach problems

Summary for Zyprexa

Prescription only

Olanzapine (Zyprexa) is an atypical antipsychotic used treat schizophrenia or bipolar disorder. It can also treat depression, in combination with fluoxetine (Prozac), when other treatments haven't worked well. This medication is thought to work by balancing the levels of certain chemicals in the brain. Olanzapine (Zyprexa) is taken by mouth, typically once daily, by adults and children. Olanzapine (Zyprexa) is also available as an injection that's usually given in a hospital or clinic setting. Some of the more common side effects of olanzapine (Zyprexa) include sleep problems, dizziness, and weight gain.

Indications for Zyprexa

Schizophrenia in adults and children age 13 years and older
Bipolar I disorder in adults and children age 13 years and older

When taken with fluoxetine (Prozac):

Bipolar depression in adults and children age 10 years and older
Depression that hasn't responded well to other treatments

Pros and Cons for Zyprexa

Pros

Taken by mouth
Taken once daily
Might notice an improvement in your symptoms in as early as a week of starting olanzapine (Zyprexa)
Available as a lower-cost generic

Cons

Can cause anticholinergic side effects, such as constipation and dry mouth
Can affect your sleep
More likely to cause weight gain, high blood cholesterol, and high blood sugar levels compared to some other atypical antipsychotics

Common Side Effects for Zyprexa

Sleepiness (29%)
Trouble sleeping (12%)
Accidental injury (12%)
Dizziness (11%)
Weakness (10%)
Dry mouth (9%)
Constipation (9%)
Upset stomach (7%)
Runny nose (7%)

Warnings for Zyprexa

Higher risk of death in older people with dementia-related psychosis
Worsening depression, suicidal thoughts and behavior
Severe allergic skin reactions
Neuroleptic malignant syndrome
Weight gain, higher blood sugar, and higher cholesterol levels
Difficulty controlling body movements
Changes in blood pressure and higher risk of falls
Risk of infection (from low white blood cell count)
Seizures
High prolactin levels
Difficulty concentrating and extreme sleepiness
Anticholinergic side effects

Prices with our coupons for Sustol vs. Zyprexa

Sustol ER1 carton / 6 kits of 10mg/0.4ml

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Olanzapine30 tablets / 5mg

$12.46$15.65

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Sustol vs. Zyprexa

Sustol

Olanzapine

Summary for Sustol

Indications for Sustol

Pros and Cons for Sustol

Pros

Cons

Common Side Effects for Sustol

Warnings for Sustol

Summary for Zyprexa

Indications for Zyprexa

Pros and Cons for Zyprexa

Pros

Cons

Common Side Effects for Zyprexa

Warnings for Zyprexa

Prices with our coupons for Sustol vs. Zyprexa

Browse medications by letter

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Sustol

Olanzapine

Summary for Sustol

Indications for Sustol

Pros and Cons for Sustol

Pros

Cons

Common Side Effects for Sustol

Warnings for Sustol

Summary for Zyprexa

Indications for Zyprexa

Pros and Cons for Zyprexa

Pros

Cons

Common Side Effects for Zyprexa

Warnings for Zyprexa