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Fluoxetine Coupon - Fluoxetine 20mg capsule

fluoxetine

Generic Prozac
Used for Depression, Panic Disorder, Obsessive-Compulsive Disorder, PTSD, Eating Disorders
Used for Depression, Panic Disorder, Obsessive-Compulsive Disorder, PTSD, Eating Disorders

Fluoxetine (Prozac) is a selective serotonin reuptake inhibitor (SSRI). It's used to treat several mental health conditions, including depression and panic disorder. The immediate-release pill and liquid are taken by mouth, typically once or twice daily. The delayed-release capsule is taken weekly, but it's approved only for depression. Some common side effects of fluoxetine (Prozac) include headaches, difficulty sleeping, and tiredness. Don't suddenly stop this medication if you've been taking it for a while; doing so can lead to symptoms of withdrawal.

Last reviewed on February 22, 2024
basics-icon

What is Fluoxetine (Prozac)?

What is Fluoxetine (Prozac) used for?

How Fluoxetine (Prozac) works

Fluoxetine (Prozac) is a selective serotonin reuptake inhibitor (SSRI). It works mainly by raising the levels of serotonin, a chemical in your brain. Serotonin plays an important role in regulating your mood and emotions.

Are you looking for information on fluoxetine (Sarafem) for premenstrual dysphoric disorder (PMDD) instead?
When does Fluoxetine (Prozac) start working?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Initial effect
Full effect

Drug Facts

Common BrandsProzac
Drug ClassSSRI
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only

More on Fluoxetine (Prozac) essentials

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What are the side effects of Fluoxetine (Prozac)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Difficulty falling asleep (up to 33%)
  • Nausea (up to 29%)
  • Headache (21%)
  • Weakness (up to 21%)
  • Diarrhea (up to 18%)
  • Low appetite (up to 17%)
  • Drowsiness (up to 17%)
  • Anxiety (up to 15%)
  • Nervousness (up to 14%)
  • Tremor (up to 13%)
  • Dry mouth (up to 12%)
  • Throat pain (up to 11%)
  • Yawning (up to 11%)
  • Low sex drive (up to 11%)

Other Side Effects

  • Abnormal dreams
  • Allergic rash
  • Flu-like symptoms

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Suicidal thoughts or behaviors
  • Serotonin syndrome: fast heart rate, dizziness, sweating, flushing, tremor (shakiness), muscle stiffness, muscle twitching or spasms, uncoordinated movement, distress, seizures, distress, hallucinations, coma
  • Seizures
  • Allergic reactions: hives, rash, blisters, swelling of the lips or tongue, difficulty breathing
  • Abnormal heart rhythm (QT prolongation): chest pounding, short of breath, chest pain, feeling faint or lightheaded
  • Severe bleeding: bruising that doesn't improve, black-colored stools, pink or red-colored urine, coughing up or vomiting blood, or unusual bleeding from the nose or gums
  • Low blood sodium levels: nausea, fatigue, headache, confusion, disoriented, hallucinations (seeing things that aren't real), seizures, unconsciousness
When do Fluoxetine (Prozac) possible side effects begin and end?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Trouble sleeping
Nausea
Diarrhea
Headache
Sexual problems
Suicidal thoughts
Seek immediate medical care if you experience this side effect.
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Hives, itching, or skin rash

inability to sit still

restlessness

Less common

Chills or fever

joint or muscle pain

Rare

Anxiety

cold sweats

confusion

convulsions (seizures)

cool pale skin

diarrhea

difficulty with concentration

drowsiness

dryness of the mouth

excessive hunger

fast or irregular heartbeat

headache

increased sweating

increased thirst

lack of energy

mood or behavior changes

overactive reflexes

purple or red spots on the skin

racing heartbeat

shakiness or unsteady walk

shivering or shaking

talking, feeling, and acting with excitement and activity you cannot control

trouble with breathing

unusual or incomplete body or facial movements

unusual tiredness or weakness

Incidence not known

Abdominal or stomach pain

agitation

back or leg pains

bleeding gums

blindness

blistering, peeling, or loosening of the skin

bloating

blood in the urine or stools

bloody, black or tarry stools

blue-yellow color blindness

blurred vision

chest pain or discomfort

clay-colored stools

constipation

continuing vomiting

cough or dry cough

dark urine

decreased urine output

decreased vision

depression

difficulty with breathing

difficulty with swallowing

dizziness or lightheadedness

eye pain

fainting

fast, pounding, or irregular heartbeat or pulse

general body swelling

high fever

hives, itching, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

hostility

indigestion

irregular or slow heart rate

irritability

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

light-colored stools

loss of appetite

loss of bladder control

muscle twitching

nausea

nightmares

no blood pressure or pulse

noisy breathing

nosebleeds

pain in the ankles or knees

painful, red lumps under the skin, mostly on the legs

pains in the stomach, side, or abdomen, possibly radiating to the back

pinpoint red spots on the skin

rapid weight gain

red or irritated eyes

red skin lesions, often with a purple center

redness, tenderness, itching, burning, or peeling of the skin

severe muscle stiffness

severe sleepiness

slurred speech

sore throat

sores, ulcers, or white spots on the lips or in the mouth

stopping of heart

sudden shortness of breath or troubled breathing

sudden weakness in the arms or legs

sudden, severe chest pain

swelling of the face, ankles, or hands

swollen or painful glands

thoughts of killing oneself

tightness in the chest

tiredness

twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs

unconsciousness

unpleasant breath odor

unusual bleeding or bruising

unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

unusually pale skin

use of extreme physical or emotional force

vomiting of blood

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Decreased appetite

Less common or rare

Abnormal dreams

breast enlargement or pain

change in sense of taste

changes in vision

feeling of warmth or heat

flushing or redness of the skin, especially on face and neck

frequent urination

hair loss

increased appetite

increased sensitivity of the skin to sunlight

menstrual pain

stomach cramps, gas, or pain

unusual secretion of milk, in females

weight loss

yawning

Incidence not known

Cracks in the skin

loss of heat from the body

painful or prolonged erections of the penis

scaly skin

swelling of the breasts or breast soreness in both females and males

unusual milk production

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Fluoxetine (Prozac)

thumbs-up

Pros

Good choice for treating depression, OCD, and panic disorder

Less likely to make you sleepy compared to some other antidepressants, such as paroxetine (Paxil)

Taken by mouth, typically once daily (IR capsules and liquid) or once weekly (DR capsules, for depression only)

Can be taken with or without food

thumbs-down

Cons

Can take up to 2 months for you to feel the full effects of the medication

Can raise the risk of suicidal thoughts and/or behavior in those age 24 or younger

Can interact with other medications, especially those affecting serotonin levels

Can cause withdrawal symptoms if you suddenly stop taking it

pharmacist-tips

Pharmacist tips for Fluoxetine (Prozac)

pharmacist
  • You can take fluoxetine (Prozac) with or without food, but fluoxetine (Prozac) also commonly causes nausea, especially when starting the medication and with dose changes; taking it with food might help with these side effects.

    • Don't change your dose or suddenly stop taking fluoxetine (Prozac) without talking to your provider first. Doing so can cause bothersome withdrawal symptoms like nausea, headache, and sleeping problems. Follow your psychiatrist's instructions to lower your dose slowly over a period of time to safely stop the medication.

      • Fluoxetine (Prozac) can cause some people to feel less hungry. Make sure you're eating a healthy and well-balanced diet while taking fluoxetine (Prozac) to ensure you're getting enough nutrition.

        • Fluoxetine (Prozac) can make you sleepy and dizzy. Don't drive or do anything requiring concentration until you know how this medication affects you.

          • Avoid drinking alcohol while taking fluoxetine (Prozac) because it can worsen some side effects (e.g., drowsiness, dizziness) as well as worsen your depression or anxiety symptoms.

            • Let your psychiatrist know if you're pregnant or thinking of becoming pregnant. They can talk with you about the benefits and risks of taking fluoxetine (Prozac) during pregnancy, as well as other treatment options. This is important because untreated mental health conditions during pregnancy can be harmful for you and your baby.

              • Fluoxetine (Prozac) can get into breastmilk and cause side effects (e.g., fussiness, sleepiness) in breastfed babies. Let your psychiatrist know if you're breastfeeding. They'll discuss the risks and benefits of continuing fluoxetine (Prozac).

                More on Fluoxetine (Prozac) tips

                faqs

                Frequently asked questions about Fluoxetine (Prozac)

                What does fluoxetine (Prozac) feel like when it starts working?
                How you feel after starting fluoxetine (Prozac) can differ depending on your medical condition and how serious your symptoms are. For example, some people who took fluoxetine (Prozac) for depression noticed feeling more energetic or having a more positive mood after a few weeks of taking fluoxetine (Prozac). But it can take 1-2 months to experience the full benefits of this medication. At the same time, you might also notice some side effects from this medication. Some of the more common ones include difficulty sleeping, headache, and nausea. Talk with your psychiatrist if you've more questions about what it might be like to take fluoxetine (Prozac).
                How long does it take for fluoxetine (Prozac) to work?
                It will take a few weeks before you notice any benefits from fluoxetine (Prozac). But it can take about 1 to 2 months before you feel the full benefits of this medication. But the exact length of time can differ depending on what medical condition you're being treated for. Keep in mind that when you first start fluoxetine (Prozac), your psychiatrist will likely prescribe a lower dose to help your body get used to this medication and watch for any side effects. Typically, if you don't notice any improvements with fluoxetine (Prozac) after taking it for about a month, your psychiatrist might raise your dose. Contact your psychiatrist if you're not sure if fluoxetine (Prozac) is working.
                Does fluoxetine (Prozac) help with anxiety?
                Fluoxetine (Prozac) isn't FDA-approved for generalized anxiety disorder (GAD). But, it's one of the first-choice options for GAD (off-label use). Talk with your psychiatrist if you've more questions about fluoxetine (Prozac) and anxiety.
                Does fluoxetine (Prozac) make you tired?
                Yes, fluoxetine (Prozac) can cause tiredness as a side effect. This medication can also make it hard for people to sleep at night, which might also lead to feeling drowsy during the day. When you first start fluoxetine (Prozac), pay attention to how this medication is affecting your sleep. If it's making you too sleepy or interrupting your sleep, contact your psychiatrist. They might recommend you change the time of day you take your dose, or they might lower your dose.
                Does fluoxetine (Prozac) cause weight gain?
                Unlike other SSRIs, fluoxetine (Prozac) isn't likely to cause weight gain. If you have any questions about fluoxetine (Prozac) and its effect on body weight, talk with your psychiatrist.
                Does fluoxetine (Prozac) cause acne?
                No, acne wasn't a reported from people taking fluoxetine (Prozac). But this medication can make you sweat more, which might cause or worsen acne. Additionally, there is a strong connection between mental health problems and acne breakouts. If you notice your acne worsening after starting fluoxetine (Prozac), ask your primary care provider or dermatologist about available treatment options.
                Do fluoxetine (Prozac) side effects go away?
                Many side effects from fluoxetine (Prozac), such as nausea or sleeping problems, can get better over time. You're more likely to experience side effects when first starting fluoxetine (Prozac) or when your provider raises your dose. But if any side effects become too bothersome for you, let your psychiatrist know. They might adjust your fluoxetine (Prozac) dose or recommend certain treatment, depending on the side effect you're experiencing.
                What happens if you miss a day of fluoxetine (Prozac)?
                If you miss a single dose of fluoxetine (Prozac), take it as soon as you remember. But if it's almost time for your next dose, just skip the missed dose and take your next dose at the next scheduled time. Never take 2 doses of fluoxetine (Prozac) to make up a missed dose. Based on the half-life of fluoxetine (Prozac), it takes about a month for most of the medication to leave your body after a single dose. So missing one dose of fluoxetine (Prozac) shouldn't affect your treatment or cause withdrawal. Still, to get the most our of the medication and to avoid any potential problems, take fluoxetine (Prozac) exactly as prescribed.
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                warings-icon

                What are the risks and warnings for Fluoxetine (Prozac)?

                Fluoxetine (Prozac) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                risk-warning

                Worsening depression, suicidal thoughts and behavior

                • Risk factors: Age under 24 years old | History of depression or other mental health conditions

                  Taking fluoxetine (Prozac) can make your depression worse and cause you to have thoughts of suicide or harming yourself. The risk is highest if you're 24 years of age or younger, during the first few weeks of taking the medication, and when your dose changes. If you or anyone around you notice that you have suicidal thoughts or unusual behavior (e.g., anxiety, panic attacks, difficulty sleeping, feeling angry or irritated, restlessness) while taking fluoxetine (Prozac), get medical help right away.

                  risk-warning

                  Anxiety and trouble sleeping

                  Fluoxetine (Prozac) can cause anxiety and trouble sleeping in some people. If this side effect is very bothersome for you, talk with your psychiatrist.

                  risk-warning

                  Serotonin syndrome

                  • Risk factors: Taking other medications that raise serotonin levels in your brain

                    Some people taking fluoxetine (Prozac) have developed a rare, but potentially life-threatening condition called serotonin syndrome. This condition happens where there's too much serotonin in the brain. Your risk for serotonin syndrome is higher if you use fluoxetine (Prozac) with other medications that can raise your serotonin levels, such as certain antidepressants, mental health medications, pain medications, and migraine medications. Let your psychiatrist know about all the medications you take before starting fluoxetine (Prozac). Also, don't start any new medications without talking to your psychiatrist first. Symptoms of serotonin syndrome include fast heart rate, sweating, muscle stiffness or spasms, fever, and confusion. Get medical help right away if you have any of these symptoms.

                    risk-warning

                    Severe allergic reactions

                    Severe allergic reactions to fluoxetine (Prozac) are possible, including life-threatening reactions like facial swelling, shock, and anaphylaxis (closing of the throat). If you notice hives, rash, red skin, swelling of the lips or tongue, or difficulty breathing after using fluoxetine (Prozac), get medical attention right away.

                    risk-warning

                    Not for use alone in bipolar disorder

                    Fluoxetine (Prozac) can be taken for depression from bipolar disorder only if it's taken together with olanzapine (Zyprexa). This is because taking fluoxetine (Prozac) alone can trigger a bipolar manic episode. Before starting fluoxetine (Prozac), your psychiatrist will check to see if you have or are at risk for bipolar disorder. Talk to your psychiatrist right away if you or your loved ones notice unusual changes in your behavior, such as racing thoughts, restlessness, getting easily distracted, or unusual talkativeness.

                    risk-warning

                    Risk of bleeding

                    • Risk factors: Taking blood-thinners or other medications that raise your risk of bleeding

                      Fluoxetine (Prozac) can raise your risk of severe bleeding or bruising, especially if you're also taking antiplatelets (e.g., aspirin, clopidogrel (Plavix)) or anticoagulants (e.g., warfarin (Coumadin), apixaban (Eliquis), rivaroxaban (Xarelto)). Get medical help if you get bruising that doesn't improve, black-colored stools, pink or red-colored urine, coughing up or vomiting blood, or unusual bleeding from the nose or gums.

                      risk-warning

                      Glaucoma

                      • Risk factors: History of angle-closure glaucoma

                        Fluoxetine (Prozac) can lead to or worsen angle-closure glaucoma. You might need to see your optometrist regularly and get eye exams to check your eyes and make sure your vision isn't worsening. Contact your optometrist or psychiatrist if you notice changes in your vision after starting fluoxetine (Prozac).

                        risk-warning

                        Low blood sodium levels

                        • Risk factors: Older adults | Taking diuretic medications

                          Fluoxetine (Prozac) can cause low blood sodium levels. Your provider might closely monitor your blood sodium levels before and during treatment with fluoxetine (Prozac). Get medical help right away if you experience weakness, confusion, difficulty concentrating, headache, or memory problems because these could be signs of low blood sodium levels, which is a medical emergency.

                          risk-warning

                          Life-threatening abnormal heart rhythm (QT prolongation)

                          • Risk factors: Low blood potassium or magnesium levels | Older age | Kidney problems | History of heart problems, slow heart rate, or other abnormal heart rhythms (arrhythmias) | Personal or family history of long QT syndrome | Taking other medications that cause QT prolongation

                            Fluoxetine (Prozac) can affect your heart rhythm, which can be serious and life-threatening. One example includes lengthening the time period from when the heart pumps and then relaxes. This is known as QT prolongation. Your risk is higher if you have certain factors, including abnormal electrolyte levels, heart rhythm problems, or are taking other medications that cause heart rhythm problems, such as amiodarone (Pacerone) and ciprofloxacin (Cipro), among others. To lower your risk, your psychiatrist or primary care provider might periodically monitor your heart and perform electrocardiograms (EKGs) to make sure your heart rhythm is normal. If you feel your chest pounding, have shortness of breath, have chest pain, or feel faint or lightheaded while taking fluoxetine (Prozac), call 911 right away.

                            dosage

                            Fluoxetine (Prozac) dosage forms

                            The average cost for 30 capsules of 20mg of Fluoxetine (Prozac) is $3.00 with a free GoodRx coupon. This is 88.07% off the average retail price of $25.16.
                            bottle of oral solution
                            Bottle of oral solution
                            DosageQuantityPrice as low asPrice per unit
                            120ml of 20mg/5ml1 bottle$33.92$33.92
                            capsule
                            Capsule
                            DosageQuantityPrice as low asPrice per unit
                            10mg30 capsules$2.70$0.09
                            20mg30 capsules$3.00$0.10
                            40mg30 capsules$4.00$0.13
                            package
                            Package
                            DosageQuantityPrice as low asPrice per unit
                            4 capsules of 90mg1 package$43.40$43.40
                            tablet
                            Tablet
                            DosageQuantityPrice as low asPrice per unit
                            10mg30 tablets$4.00$0.13
                            20mg30 tablets$10.20$0.34
                            60mg30 tablets$12.60$0.42

                            Typical dosing for Fluoxetine (Prozac)

                            In general, your psychiatrist will have you start with lower dose of fluoxetine (Prozac) and raise it slowly over a few weeks. If your total daily dose is higher than 20 mg, they might ask you to split the dose and take it twice daily.

                            Immediate-release capsule:

                            • Major depressive disorder (MDD)

                              • Adults: The typical starting dose is 20 mg by mouth daily in the morning. The maximum recommended dose is 80 mg daily total.

                              • Children ages 8 years and older: The typical dose ranges between 10 mg to 20 mg by mouth once daily.

                            • Obsessive compulsive disorder (OCD)

                              • Adults: The typical starting dose is 20 mg by mouth daily in the morning. The maximum recommended dose is 80 mg daily total.

                              • Children ages 7 years and older: The typical starting dose ranges from 10 mg to 20 mg by mouth once daily, depending on body weight. The typical maintenance dose ranges from 20 mg to 60 mg daily.

                            • Bulimia

                              • Adults: The typical maintenance dose is 60 mg by mouth once daily in the morning.

                            • Panic disorder

                              • Adults: The typical starting dose is 10 mg by mouth once daily. The typical maintenance dose is 20 mg daily. The maximum recommended dose is 60 mg daily.

                            • Depression from bipolar 1 disorder

                              • Adults and children ages 10 years and older: The typical dose ranges from 20 mg to 50 mg by mouth daily, taken along with olanzapine (Zyprexa).

                            • Treatment resistant depression

                              • Adults: The typical dose ranges from 20 mg to 50 mg by mouth daily, taken along with olanzapine (Zyprexa).

                            Immediate-release fluoxetine also comes as tablet and liquid, but these only treat MDD, OCD, bulimia, and panic disorder.

                            Delayed-release capsule:

                            • Depression (ages 7 years and older): The typical dose is 90 mg by mouth once weekly. Your provider will let you know if and when you can transition to the fluoxetine (Prozac) DR capsule. Usually, you can start this medication a week after the last daily dose of fluoxetine (Prozac) 20 mg.

                            More on Fluoxetine (Prozac) dosage forms

                            interactions

                            Interactions between Fluoxetine (Prozac) and other drugs

                            Fluoxetine (Prozac) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Fluoxetine (Prozac). Please note that only the generic name of each medication is listed below.

                            Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                            Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                            Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                            drug-cost

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                            contraindications-icon

                            Fluoxetine (Prozac) contraindications

                            Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Fluoxetine (Prozac) will not be safe for you to take.
                            alternatives

                            What are alternatives to Fluoxetine (Prozac)?

                            There are a number of medications that your doctor can prescribe in place of Fluoxetine (Prozac). Compare a few possible alternatives below.
                            latest news

                            What is the latest news about Fluoxetine (Prozac)?

                            images

                            Fluoxetine (Prozac) images

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                            References

                            Best studies we found

                            American College of Obstetricians and Gynecologists. (202). Depression during pregnancy

                            Aurobindo Pharma Limited. (2024). FLUOXETINE - fluoxetine hydrochloride capsule [package insert]. DailyMed.

                            Dr.Reddy's Laboratories Limited. (2021). FLUOXETINE HYDROCHLORIDE capsule, delayed release pellets [package insert]. DailyMed.

                            View All References (6)

                            Lannett Company, Inc. (2023). FLUOXETINE- fluoxetine hydrochloride liquid [package insert]. DailyMed.

                            Marken, P. A., et al. (2000). Selecting a selective serotonin reuptake inhibitor: Clinically important distinguishing features. Primary Care Companion to the Journal of Clinical Psychiatry.

                            Powers, M., et al. (2015). Clinical Practice Review for GAD. Anxiety and Depression Association of America.

                            ScieGen Pharmaceuticals, Inc. (2023). FLUOXETINE- fluoxetine hydrochloride tablet [package insert]. DailyMed.

                            Wichniak, A., et al. (2017). Effects of Antidepressants on Sleep. Current Psychiatry Reports.

                            Zajecka, J., et al. (1999). Changes in adverse events reported by patients during 6 months of fluoxetine therapy. Journal of Clinical Psychiatry.

                            GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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