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Warfarin Coupon - Warfarin 5mg tablet

warfarin

Generic Coumadin, Jantoven
Used for Atrial Fibrillation, Heart Attack, Deep Vein Thrombosis, Pulmonary Embolism
Used for Atrial Fibrillation, Heart Attack, Deep Vein Thrombosis, Pulmonary Embolism

Warfarin (Coumadin) is a blood thinner (anticoagulant). It's used to prevent and treat blood clots in adults and children with conditions such as deep vein thrombosis (DVT) or pulmonary embolism (PE). Warfarin (Coumadin) is taken by mouth, typically once daily. Your provider will adjust the dose based on your international normalized ratio (INR). Taking too much warfarin (Coumadin) can lead to side effects like bruising and serious bleeding. If needed, your provider can give you an antidote to reverse the effects of warfarin (Coumadin).

Reviewed by:
reviewer
Robert Chad Hakim, PharmD, BCCCP
reviewer
Kristianne Hannemann, PharmD
Last reviewed on December 6, 2023
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostContraindicationsAlternativesLatest newsImagesReferencesPricesMedicare
basics-icon

What is Warfarin (Coumadin)?

What is Warfarin (Coumadin) used for?

  • Prevention and treatment blood clots in the veins

  • Prevention and treatment blood clots linked to atrial fibrillation (AFib) or heart valve replacement

  • Prevention of more blood clots and to lower risk of death after a heart attack

How Warfarin (Coumadin) works

Warfarin (Coumadin) is a blood thinner. It's also known as a vitamin K antagonist, meaning it stops vitamin K from working properly. Your body typically uses vitamin K to make blood clots. Warfarin (Coumadin) prevents blood clots from forming by blocking vitamin K.

Drug Facts

Common BrandsJantoven, Coumadin (brand no longer available)
Drug ClassVitamin K antagonist
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only

More on Warfarin (Coumadin) essentials

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Written by Justin DeFlorian, PharmD, BCPS
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What are the side effects of Warfarin (Coumadin)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Bleeding
  • Bruising

Other Side Effects

  • Rash
  • Nausea
  • Vomiting
  • Diarrhea
  • Chills
  • Itching
  • Change in taste

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Severe bleeding: feeling faint, lightheaded, dizziness, vomiting blood, bloody or dark-colored stools, severe stomach pain or discomfort
  • Calcium build-up in the blood vessels (calciphylaxis): skin discoloration, skin sores, painful lumps in the skin, skin infections
  • Skin or tissue death and gangrene: skin discoloration (especially darkened skin color), swelling, blisters, sudden and severe pain in skin, numbness

Source: DailyMed

More on Warfarin (Coumadin) side effects

warfarin: side effects warfarin

6 Warfarin Side Effects You Should Know About

Written by Justin DeFlorian, PharmD, BCPS

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Bleeding gums

blood in the urine

bloody stools

blurred vision

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

chest pain or discomfort

confusion

coughing up blood

difficulty with breathing or swallowing

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

excessive bruising

headache

increased menstrual flow or vaginal bleeding

nosebleeds

paralysis

peeling of the skin

prolonged bleeding from cuts

red or black, tarry stools

red or dark brown urine

stomach pain with cramping

sweating

unexplained swelling

unusual tiredness or weakness

Rare

Arm, back, or jaw pain

blue-green to black skin discoloration

blue or purple toes

change in consciousness

chest tightness or heaviness

chills

clay-colored stools

diarrhea

dizziness

fainting or loss of consciousness

fast or irregular breathing

fast or irregular heartbeat

fever

itching or skin rash

light-colored stools

loss of appetite

nausea and vomiting

pain in the toes

pain, redness, or sloughing of the skin

pale skin

purplish red, net-like, blotchy spots on the skin

skin blisters

small red or purple spots on the skin

stomach pain

swelling of the eyes or eyelids

troubled breathing with exertion

unpleasant breath odor

unusual bleeding or bruising

upper right stomach pain

vomiting of blood

yellow eyes and skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Joint pain

muscle pain

Rare

Bloated

change in taste, or bad, unusual, or unpleasant (after) taste

cold intolerance

excess air or gas in the stomach or intestines

full feeling

general feeling of discomfort or illness

hair loss or thinning of the hair

hives or welts

lack or loss of strength

pain

passing gas

red, sore, or itching skin

sores, welting, or blisters

unusual drowsiness, dullness, or feeling of sluggishness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Warfarin (Coumadin)

thumbs-up

Pros

Each strength of tablet is a unique color, making it easy to tell them apart

Only needs to be taken once a day

Has an antidote available in case of an emergency

Available as a lower-cost generic

thumbs-down

Cons

Only prevents new blood clots from forming or getting bigger; it doesn't work on existing blood clots

Requires regular blood draws to check INR levels

Interacts with foods and many commonly-prescribed medications

Not safe to take during pregnancy

pharmacist-tips

Pharmacist tips for Warfarin (Coumadin)

pharmacist

  • Mark your calendar with your appointments to see your provider and get any blood work done (e.g., INR, blood cell count). This will help make sure the medication is working well for you and you're not having side effects.

    • You can take warfarin (Coumadin) with or without food. If it's hurting your stomach, taking it with food can help.

      • Be consistent with the time of day you take your warfarin (Coumadin) dose as well as how much vitamin K-rich foods you eat. This will help make sure you respond to the medication well and that your INR result is where it should be. Talk to your provider if you have significant changes in your diet, health, or timing of your doses. You might need to get your INR checked sooner.

        • Take warfarin (Coumadin) exactly as your provider tells you. Make sure you know your prescribed warfarin (Coumadin) dose and the tablet sizes you have. It's possible you might need to take more than one strength, have to split tablets in half, or skip doses on certain days of the week. Ask your provider if you're not sure what your warfarin (Coumadin) dose is.

          • Warfarin (Coumadin) can make you bleed and bruise more easily. Be careful with high-impact activities or sports while taking this medication and for 5 days after your last dose. Stop taking the medication and get medical help right away if you feel lightheaded, dizzy, are vomiting or coughing up blood, or have blood in your stool. These are signs of bleeding that might be happening in your body.

            • Get medical help right away if you fall and hit your head, especially if you feel dizzy or have a headache. Your provider will want to check to make sure you don't have any brain bleeds.

              • If you're going to have a dental procedure or surgery, make sure your dentist or surgeon knows you're taking warfarin (Coumadin) and which provider prescribed it for you. You might have to temporarily stop your warfarin (Coumadin) a few days before the procedure.

                • Warfarin (Coumadin) can interact with many medications and supplements. Make sure your provider knows which medications you're taking, especially if you're taking a medication that can cause bleeding or supplements containing vitamin K. They might want to check your INR more often after you start anything new.

                  faqs

                  Frequently asked questions about Warfarin (Coumadin)

                  Is warfarin (Coumadin) an anticoagulant?
                  Yes, warfarin (Coumadin) is an anticoagulant (blood thinner). More specifically, it's a vitamin K antagonist that prevents blood clots by blocking vitamin K from working properly.
                  What are the best foods to eat while taking warfarin (Coumadin)?
                  There aren't any specific foods that you must eat or must avoid while taking warfarin (Coumadin). The most important thing is to be consistent with how much vitamin K-rich foods you eat, such as spinach and brussel sprouts. This is because vitamin K affects how well warfarin (Coumadin) works. When you're consistent with your diet, your vitamin K levels stays more steady. If your make changes to your diet while taking warfarin (Coumadin), let your provider know because they will probably want to check your INR to make sure it's within a safe range.
                  Can you eat eggs while on warfarin (Coumadin)?
                  Yes, you can eat eggs while taking warfarin (Coumadin). Eggs contain low levels of vitamin K. Eating eggs shouldn't affect how well warfarin (Coumadin) works.
                  Why should I take warfarin (Coumadin) in the evening?
                  Your provider might recommend you to take warfarin (Coumadin) in the evening. This is likely because blood draws for INR are often scheduled for the morning. If your provider want to make a dose change based on INR results, they can do so that same day if you take warfarin (Coumadin) in the evening. Research shows that taking warfarin (Coumadin) in the evening doesn't make it work any better. The most important thing is to take it at the same time every day. Figure out a time of the day that's most convenient for you to take warfarin (Coumadin) where you're likely to not miss doses. Otherwise, your INR might not be accurate, which can raise your risk for bleeds or clots.
                  How is the warfarin (Coumadin) dose adjusted based on INR?
                  Your provider will target a "goal" INR based on what medical condition you're taking warfarin (Coumadin) for. Typically, your provider will have you start on a dose of warfarin (Coumadin) ranging from 2 mg to 5 mg by mouth once a day. Then, they'll check your INR with blood draws after a few days. And once your INR becomes more stable, your provider will adjust the warfarin (Coumadin) dose as needed to stay within that "goal" INR. Keep in mind that different factors, like what food you're eating and what other medications you're taking, can also affect INR. So your provider will check INR regularly to make sure you're within a safe range.
                  What is a dangerous INR level on warfarin (Coumadin)?
                  Your provider will target a "goal" INR based on what medical condition you have. They'll check your INR level regularly to make sure it's not too high or low. If your INR level is too high, then you're more likely to have a serious bleed. Your provider might ask you to skip a few doses of warfarin (Coumadin) so that the INR level can go back down. If your INR level is too low, then you're at higher risk for blood clots and your provider will likely need to raise your warfarin (Coumadin) dose.
                  What is the antidote for warfarin (Coumadin)?
                  Your provider will give you an antidote for warfarin (Coumadin) if you've a high INR level and you're actively bleeding. The antidote is called prothrombin complex concentrate (Kcentra, Balfaxar). It contains proteins that help form blood clots in order to stop bleeding caused by too much warfarin (Coumadin). Since these proteins need vitamin K to work, your provider will likely also give you vitamin K (phytonadione) as well.
                  How long does warfarin (Coumadin) take to work?
                  It takes about 1 to 3 days to start to see the effects of warfarin (Coumadin). But the maximum effect of warfarin (Coumadin) isn't seen until 5 to 7 days later. For this reason, providers typically wait a few days to see how your INR responds to warfarin (Coumadin) before adjusting the dose. It's important to take warfarin (Coumadin) exactly as prescribed and at the same time every day.
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                  warings-icon

                  What are the risks and warnings for Warfarin (Coumadin)?

                  Warfarin (Coumadin) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                  risk-warning

                  Severe or life-threatening bleeding

                  • Risk factors: Higher-than-recommended INR | Age greater than 65 years | Bleeding problems or injury | High blood pressure | Kidney or liver problems | Cancer | Taking other medications that raise your risk for bleeding | Drinking alcohol


                    Taking warfarin (Coumadin) can raise your risk for bleeds. Your provider will check your INR regularly to make sure it's within a safe range. Keep in mind that other medications and foods can interact with warfarin (Coumadin) and affect how well it works. Your provider might check your INR more often any time you start or stop a medication, or make changes to your diet.

                    Get immediate medical attention if you fall and hit your head so your care team can check for signs of bleeding on the inside of your body. Also, get help right away if you notice blood in your urine, have bright red or dark, tarry "coffee ground" stool, cough or vomit blood, or can't stop bleeding from a wound.

                    If you do have a serious bleed, your provider will give you prothrombin complex concentrate (Kcentra, Balfaxar) and vitamin K (phytonadione) to reverse the effects of warfarin (Coumadin).

                    risk-warning

                    Risk of blood clots from stopping too early

                    Don't skip doses or suddenly stop taking warfarin (Coumadin) unless your provider specifically told you it's safe to do so. This raises your risk of blood clots to form in your body. If you're wanting to stop warfarin (Coumadin), contact your provider so they can create a safe plan for you. Go to the hospital if you experience symptoms of blood clots, such as:
                    - Stroke: sudden numbness or weakness on one side of the body, feeling confused, trouble speaking or understanding speech, dizziness, trouble keeping balance
                    - Blood clot in the leg or arm: swelling or redness in arms or legs, skin that's warm to touch
                    - Blood clot in the lungs: trouble breathing, chest pain, cough, irregular heartbeat

                    risk-warning

                    Risk of fat-containing clots

                    Taking warfarin (Coumadin) can raise your risk of clots made of fat to be released into your blood. Like blood clots, they can get trapped into smaller blood vessels and stop blood flow to important organs. The most commonly involved organs are the kidneys, pancreas, spleen, and liver. It can also happen in your feet, which can cause your toes to turn a dark purple or blue color (a problem called "purple toe syndrome"). If you notice any skin color changes after starting warfarin (Coumadin), talk to your provider right away, as you'll need to stop the medication.

                    risk-warning

                    Calcium build-up in blood vessels (calciphylaxis)

                    Although rare, warfarin (Coumadin) can cause a potentially serious and life-threatening condition called calciphylaxis. This is when calcium builds up in the blood vessels. When this happens, there's less room for blood to flow through your vessels. Symptoms include skin discoloration, skin sores, painful lumps in the skin, or skin infections. Seek medical help right away if you notice any significant skin changes while taking warfarin (Coumadin).

                    risk-warning

                    Skin or tissue death and risk of gangrene

                    • Risk factors: Use in people with heparin-induced thrombocytopenia (HIT) or HIT with thrombosis syndrome (HITTS)

                      Although rare, taking warfarin (Coumadin) can cause blood flow problems to the skin, which can lead to skin tissue death (called necrosis) and gangrene. This side effect has been reported as early as within a few days of starting warfarin (Coumadin). While the cause isn't clear, it's likely related to clotting problems.

                      This side effect can also happen in people with heparin-induced thrombocytopenia (HIT), which is a severe reaction to heparin.

                      Seek medical help right away if you notice skin discoloration (especially darkened skin color), swelling, blisters, sudden and severe pain in skin, numbness. Your provider will likely ask you to stop taking warfarin (Coumadin).

                      risk-warning

                      Not for use during pregnancy

                      Warfarin (Coumadin) can cause birth defects and severe harm to babies and mothers. This medication shouldn't be used in pregnancy unless the benefit is clearly greater than the risk, such as in people who are at high risk for clots. Your provider might test you for pregnancy before starting warfarin (Coumadin). If you're able to become pregnant, use birth control (contraception) during, and for at least one month after, stopping warfarin (Coumadin). Talk to your provider right away if you become pregnant or are thinking of becoming pregnant.

                      dosage

                      Warfarin (Coumadin) dosage forms

                      The average cost for 30 tablets of 5mg of Warfarin (Coumadin) is $4.00 with a free GoodRx coupon. This is 64.89% off the average retail price of $11.39.
                      tablet
                      Tablet
                      DosageQuantityPrice as low asPrice per unit
                      1mg90 tablets$10.00$0.11
                      2mg90 tablets$10.00$0.11
                      2.5mg90 tablets$10.00$0.11
                      3mg90 tablets$10.00$0.11
                      4mg90 tablets$10.00$0.11
                      5mg30 tablets$4.00$0.13
                      6mg90 tablets$10.00$0.11
                      7.5mg90 tablets$10.00$0.11
                      10mg90 tablets$10.00$0.11

                      Typical dosing for Warfarin (Coumadin)

                      More on Warfarin (Coumadin) dosage forms

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                      Warfarin Dosages: Your GoodRx Guide

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                      interactions

                      Interactions between Warfarin (Coumadin) and other drugs

                      Warfarin (Coumadin) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Warfarin (Coumadin). Please note that only the generic name of each medication is listed below.

                      More on Warfarin (Coumadin) interactions

                      Warfarin: drug interaction warfarin

                      10 Warfarin Interactions to Watch Out For

                      Written by Daphne Berryhill, RPh

                      Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                      Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                      Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                      drug-cost

                      How much does Warfarin (Coumadin) cost?

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                      contraindications-icon

                      Warfarin (Coumadin) contraindications

                      Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Warfarin (Coumadin) will not be safe for you to take.

                      • Pregnancy (except for those with artificial heart valves who are at risk for clots)

                      • Abortion or pregnancy complications (e.g., eclampsia or pre-eclampsia)

                      • Active bleeding, easily bleed, or bleeding problems

                      • Recent surgery, or having surgery soon, in the brain, spinal cord, eye, or trauma surgery that requires large open surfaces

                      • Inability to be consistent with taking warfarin (Coumadin)

                      • Spinal puncture, or other procedures with potential to cause uncontrolled bleeding

                      • Major regional or lumbar block anesthesia

                      • Severely high blood pressure (malignant hypertension)

                      alternatives

                      What are alternatives to Warfarin (Coumadin)?

                      There are a number of medications that your doctor can prescribe in place of Warfarin (Coumadin). Compare a few possible alternatives below.
                      Warfarin (Coumadin)
                      Used for:

                      • Prevention and treatment blood clots in the veins

                      • Prevention and treatment blood clots linked to atrial fibrillation (AFib) or heart valve replacement

                      • Prevention of more blood clots and to lower risk of death after a heart attack

                      $4.00 Lowest GoodRx priceView Prices
                      Eliquis (apixaban)
                      Used for:

                      • Treat blood clots and lower the risk of new clots in children from birth and older

                      $594.55 Lowest GoodRx priceView Prices
                      Xarelto (rivaroxaban)
                      Used for:
                      $170.96 Lowest GoodRx priceView Prices
                      latest news

                      What is the latest news about Warfarin (Coumadin)?

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                      Deep vein thrombosis causes blood clots to form, normally in the leg. Learn more about the treatments used to ease and prevent this condition.

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                      images

                      Warfarin (Coumadin) images

                      Peach Oblong Tv 5 And 1721 - Warfarin Sodium 5mg Tablet
                      This medicine is Peach, Oblong, Scored Tablet Imprinted With "1721" And "Tv 5".Peach Oblong Tv 5 And 1721 - Warfarin Sodium 5mg Tablet
                      Peach Oblong Tv 5 And 1721 - Warfarin Sodium 5mg Tablet
                      This medicine is Peach, Oblong, Scored Tablet Imprinted With "1721" And "Tv 5".Peach Oblong Tv 5 And 1721 - Warfarin Sodium 5mg Tablet
                      Peach Oblong Warfarin Taro And 5 - Warfarin Sodium 5mg Tablet
                      This medicine is Peach, Oblong, Scored Tablet Imprinted With "5" And "Warfarin Taro".Peach Oblong Warfarin Taro And 5 - Warfarin Sodium 5mg Tablet
                      Peach Round I G And W 5 - Warfarin Sodium 5mg Tablet
                      This medicine is Peach, Round, Scored Tablet Imprinted With "I G" And "W 5".Peach Round I G And W 5 - Warfarin Sodium 5mg Tablet

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                      References

                      Best studies we found

                      Buttolph, A., et al. (2023). Gangrene. StatPearls.

                      Garrison, S. R., et al. (2020). The effect of warfarin administration time on anticoagulation stability (INRange): A pragmatic randomized controlled trial. Annals of Family Medicine.

                      Naranjo, M., et al. (2023). Malignant hypertension. StatPearls.

                      View All References (5)

                      National Institutes of Health, Office of Dietary Supplements. (2021). Vitamin K: Fact sheet for health professionals.

                      Patel, S., et al. (2023). Warfarin. StatPearls.

                      Scrinivasan, A. F., et al. (2004). Warfarin-induced skin necrosis and venous limb gangrene in the setting of heparin-induced thrombocytopenia. Archives of Internal Medicine.

                      Upsher-Smith Laboratories, LLC. (2023). Jantoven- warfarin sodium tablet [package insert]. DailyMed.

                      Westphal, S. G., et al. (2023). Calciphylaxis. StatPearls.

                      GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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