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Compare Caplyta vs. Vraylar

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Caplyta (lumateperone)
    Vraylar (cariprazine)
  • Caplyta (lumateperone)
    Vraylar (cariprazine)

  • Summary of Caplyta vs. Vraylar

    Summary for Atypical antipsychotic
    Prescription only

    Caplyta (lumateperone) is an atypical antipsychotic. It's used to treat schizophrenia and depression related to bipolar disorder in adults. Caplyta (lumateperone) is taken by mouth, typically once daily. Common side effects of this medication include drowsiness, nausea, and dizziness. Caplyta (lumateperone) is brand name only and isn't available as a generic.

    Summary for Atypical antipsychotic
    Prescription only

    Vraylar (cariprazine) is an atypical antipsychotic used to treat schizophrenia and bipolar I disorder in adults. It can also be used as an add-on medication to help with major depressive disorder (MDD). Vraylar (cariprazine) is taken by mouth once a day. Some common side effects of this medication include uncontrolled muscle movements, headache, and restlessness. Unlike some other antipsychotic medications, Vraylar (cariprazine) causes minimal weight gain. Vraylar (cariprazine) is brand name only and not available as a generic medication.

  • Indications of Caplyta vs. Vraylar

    Indications for
    •Schizophrenia
    •Bipolar depression, with or without lithium (Lithobid) or valproate
    Indications for
    •Schizophrenia
    •Manic or mixed episodes of bipolar I disorder
    •Bipolar depression of bipolar I disorder
    •Major depressive disorder (MDD), as an add-on medication

  • Pros and Cons of Caplyta vs. Vraylar

    Pros and Const for Atypical antipsychotic
    Pros
    •Taken once daily
    •Less likely to cause movement disorders compared to other antipsychotics
    •Less likely to cause weight gain than most other antipsychotics
    Cons
    •Might take a few weeks to see more noticeable improvements in your symptoms
    •Not approved for children
    •Commonly causes drowsiness as a side effect
    Pros and Const for Atypical antipsychotic
    Pros
    •Taken once a day
    •Can be taken with or without food
    •Works in your body for a longer period of time than other similar medications
    Cons
    •You might have to see your healthcare provider several times until you find a dose that works best for you.
    •Higher risk for uncontrolled muscle movements than some similar medications
    •Might take several weeks before you experience the full effects of this medication

  • Common Side Effects of Caplyta vs. Vraylar

    Common Side Effects for

    Schizophrenia

    •Sleepiness (24%)
    •Nausea (9%)
    •Dry mouth (6%)
    •Dizziness (5%)

    Bipolar depression

    •Headache (14%)
    •Sleepiness (13%)
    •Dizziness (8%)
    •Nausea (8%)
    •Dry mouth (5%)
    Common Side Effects for
    •Uncontrolled muscle movements (up to 20%)
    •Headache (up to 18%)
    •Restlessness (up to 14%)
    •Trouble sleeping (up to 13%)
    •Constipation (up to 10%)
    •Nausea (up to 8%)
    •Stomach pain (up to 7%)
    •Toothache (up to 6%)

  • Warnings of Caplyta vs. Vraylar

    Common Side Effects for
    •Higher risk of death in older adults with dementia-related psychosis
    •Worsening depression, suicidal thoughts and behavior
    •Neuroleptic malignant syndrome
    •Movement problems
    •High blood sugar, high cholesterol, and weight gain
    •Low white blood cells
    •Changes in blood pressure and heartbeat
    •Seizures
    Common Side Effects for
    •Higher risk of death in older adults with dementia-related psychosis
    •Suicidal thoughts and behavior
    •Neuroleptic malignant syndrome
    •High blood sugar, high cholesterol, and weight gain
    •Difficulty controlling movements (tardive dyskinesia)
    •Higher risk of infections
    •Higher risk of falls
    •Trouble controlling body temperature
    •Difficulty swallowing
    •Seizures

  • Prices with our coupons for Caplyta vs. Vraylar

    Learn more about Caplyta
    Learn more about Vraylar

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