Key takeaways
Gabapentin (Neurontin) and fluphenazine (Prolixin) are both prescription medications, but they are used for different conditions and belong to different drug classes. Gabapentin is an antiepileptic used to treat certain seizures and nerve pain, while fluphenazine is a typical antipsychotic used to treat psychotic disorders. Gabapentin is available in generic form and can be taken as a tablet, capsule, or liquid, typically three times a day. In contrast, fluphenazine is also available in generic form and can be taken as a tablet, liquid, or injection, with the long-acting injection given every 4 to 6 weeks. Gabapentin works by affecting nerve activity, whereas fluphenazine works by blocking dopamine activity in the brain. Common side effects of gabapentin include dizziness and sleepiness, while fluphenazine can cause drowsiness and movement problems. Additionally, gabapentin can raise the risk of suicidal thoughts, whereas fluphenazine can lead to serious movement disorders and is not safe for older adults with dementia-related psychosis.
