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Compare Neurontin vs. Imitrex

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Gabapentin (Neurontin) and Sumatriptan (Imitrex) are both prescription medications, but they are used for different conditions and belong to different drug classes. Gabapentin is an antiepileptic used to treat certain seizures and nerve pain, while Sumatriptan is a triptan used to treat migraines. Gabapentin is typically taken three times daily and is available in generic form as pills and a liquid. In contrast, Sumatriptan is taken as a single dose at the onset of a migraine, with the option to take a second dose after two hours if needed, and is also available as a lower-cost generic tablet. Gabapentin can cause dizziness and sleepiness, and it has a risk of misuse, leading some states to classify it as a controlled substance. Sumatriptan can cause tingling, numbness, and fatigue, and it has serious risks like heart problems and serotonin syndrome, especially when taken with certain other medications. Gabapentin is used for ongoing conditions and requires careful dose adjustments, while Sumatriptan is used for acute migraine relief and has strict limits on how often it can be taken.

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