Compare Neurontin vs. Depakote

Gabapentin (Neurontin) and Divalproex (Depakote) are both antiepileptic medications, but they have different uses and forms. Gabapentin is used to treat certain seizures and nerve pain, while Divalproex is used for seizures, bipolar disorder, and migraine prevention. Gabapentin is available as a lower-cost generic in tablets, capsules, and liquid forms, and is typically taken three times a day. In contrast, Divalproex comes in delayed-release and extended-release tablets, as well as sprinkle capsules, and is usually taken once or twice daily. Gabapentin can cause dizziness and sleepiness, and it may be misused, leading some states to classify it as a controlled substance. Divalproex, on the other hand, can cause weight changes, liver problems, and requires regular blood tests to monitor liver health. Both medications should not be stopped suddenly to avoid withdrawal symptoms, including seizures.