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Compare Mirapex vs. Neurontin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Pramipexole (Mirapex, Mirapex ER) and gabapentin (Neurontin) are both prescription medications, but they are used to treat different conditions and belong to different drug classes. Pramipexole is a dopamine agonist used to treat Parkinson's disease and restless legs syndrome (RLS), while gabapentin is an antiepileptic used to treat certain seizures and nerve pain. Pramipexole is available in both immediate-release and extended-release forms, with the immediate-release needing to be taken three times a day and the extended-release taken once daily. Gabapentin, on the other hand, is typically taken three times daily and is available as tablets, capsules, and liquid. Both medications can cause sleepiness and dizziness. Addition side effects of pramipexole include nausea, and constipation, whereas gabapentin commonly causes por muscle control. Additionally, pramipexole can cause compulsive behaviors and hallucinations, while gabapentin can raise the risk of suicidal thoughts and breathing problems. Both medications should not be stopped suddenly without consulting your healthcare provider due to the risk of withdrawal symptoms.

  • Pramipexole
    Gabapentin (Neurontin)
  • Pramipexole
    Gabapentin (Neurontin)

  • Summary of Mirapex vs. Neurontin

    Summary for Dopamine agonist
    Prescription only

    Pramipexole is used to treat Parkinson's disease (PD) and restless legs syndrome (RLS). The dosage depends on what form you’re taking: the immediate-release tablet is taken 3 times per day and the extended-release tablet is taken once per day. The immediate-release is only available as a lower-cost generic (the brand name Mirapex has been discontinued in the US). The extended-release version of this medication is available as brand (Mirapex ER) and generic. Side effects include nausea, drowsiness, dizziness, and tiredness.

    Summary for Antiepileptic
    Prescription only

    Gabapentin (Neurontin) is a medication approved to treat certain seizures and nerve pain. It's typically taken 3 times daily by mouth, and is available as pills and a liquid. Common side effects include dizziness and sleepiness.

  • Indications of Mirapex vs. Neurontin

    Indications for
    •Parkinson's disease
    •Moderate-to-severe restless legs syndrome - immediate-release tablets only
    Indications for
    •Nerve pain from shingles in adults
    •Add on treatment for partial (focal) seizures in people age 3 years and older

  • Pros and Cons of Mirapex vs. Neurontin

    Pros and Const for Dopamine agonist
    Pros
    •Works well to control movement problems
    •Available in a lower-cost generic version
    •Extended-release tablet can be taken once daily
    Cons
    •Only available as a tablet
    •Can cause extreme sleepiness
    •Immediate-release tablets need to be taken 3 times per day.
    Pros and Const for Antiepileptic
    Pros
    •Works well for seizures and nerve pain
    •Available as a lower-cost generic
    •Available as a tablet, capsule, and liquid for those who have trouble swallowing pills
    •Dose can be adjusted based on response
    Cons
    •Needs to be taken multiple times per day
    •Stopping the medication suddenly can lead to serious problems, such as seizures
    •Can raise your risk of suicidal thoughts or behavior
    •Commonly causes dizziness

  • Common Side Effects of Mirapex vs. Neurontin

    Common Side Effects for

    Early Parkinson’s disease (PD)

    •Sleepiness (33-36%)
    •Nausea (22-24%)
    •Constipation (12-14%)
    •Dizziness (12%)
    •Swelling in arms or legs (5-8%)
    •Fatigue (6%)
    •Hallucinations (5-6%)
    •Dry mouth (4-5%)

    Restless legs syndrome

    •Nausea (16%)
    •Headache (16%)
    •Fatigue (9%)
    •Sleepiness (6%)
    •Constipation (4%)
    Common Side Effects for
    •Dizziness (17-28%)
    •Sleepiness (19-21%)
    •Poor muscle control/clumsiness (3-13%)
    •Fatigue (3-11%)

  • Warnings of Mirapex vs. Neurontin

    Common Side Effects for
    •Extreme sleepiness
    •Changes in blood pressure and higher risk of falls
    •Intense urges
    •Hallucinations and behavior changes
    •Difficulty controlling body movements
    •Changes to your posture
    •Severe muscle damage (rhabdomyolysis)
    •Worsening symptoms of RLS
    Common Side Effects for
    •Severe allergic and skin reactions
    •Difficulty concentrating, extreme sleepiness, and dizziness
    •Withdrawal problems
    •Suicidal thoughts or behavior
    •Dangerously slow breathing (respiratory depression)
    •Brain and mental health side effects in children

  • Prices with our coupons for Mirapex vs. Neurontin

    Learn more about Pramipexole
    Learn more about Gabapentin

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