Key takeaways
Gabapentin (Neurontin) and Desipramine (Norpramin) are both prescription medications, but they belong to different drug classes and treat different conditions. Gabapentin is an antiepileptic used to treat certain seizures and nerve pain, while Desipramine is a tricyclic antidepressant (TCA) used to treat depression. Gabapentin is typically taken three times a day and is available in generic form as pills and a liquid. In contrast, Desipramine is usually taken once a day and also comes in a generic form. Gabapentin has a risk of misuse, leading some states to classify it as a controlled substance. Both medications can cause side effects like sleepiness, dizziness, confusion, and weight gain. Both medications can raise the risk of suicidal thoughts, but Desipramine is not a first-choice treatment for depression due to its side effects.
