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Compare Lyrica vs. Neurontin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Pregabalin (Lyrica)
    Gabapentin (Neurontin)
  • Pregabalin (Lyrica)
    Gabapentin (Neurontin)

  • Summary of Lyrica vs. Neurontin

    Summary for Antiepileptic
    Prescription only

    Pregabalin (Lyrica) treats pain caused by nerve damage and fibromyalgia in adults. It can be used with other medications to prevent seizures for both adults and children. Pregabalin (Lyrica) is taken by mouth, typically 2 or 3 times a day. It's available as a capsule and oral solution. Some of the more common side effects of this medication include dizziness and drowsiness.

    Summary for Antiepileptic
    Prescription only

    Gabapentin (Neurontin) is a medication approved to treat certain seizures and nerve pain. It's typically taken 3 times daily by mouth, and is available as pills and a liquid. Common side effects include dizziness and sleepiness.

  • Indications of Lyrica vs. Neurontin

    Indications for
    •Nerve pain from diabetes (diabetic peripheral neuropathy), shingles (postherpetic neuralgia), or spinal cord injury
    •Fibromyalgia
    •Partial-onset seizures
    Indications for
    •Nerve pain from shingles in adults
    •Add on treatment for partial (focal) seizures in people age 3 years and older

  • Pros and Cons of Lyrica vs. Neurontin

    Pros and Const for Antiepileptic
    Pros
    •Works well to relieve nerve pain caused by diabetes, shingles, and spinal cord injuries
    •Available in a capsule and oral solution
    •Used in combination with other anti-seizure drugs to treat partial-onset seizures
    •Available as a lower-cost generic
    Cons
    •Can cause dizziness and drowsiness
    •Must avoid drinking alcohol
    •Not recommended for breastfeeding females
    •Can cause weight gain
    Pros and Const for Antiepileptic
    Pros
    •Works well for seizures and nerve pain
    •Available as a lower-cost generic
    •Available as a tablet, capsule, and liquid for those who have trouble swallowing pills
    •Dose can be adjusted based on response
    Cons
    •Needs to be taken multiple times per day
    •Stopping the medication suddenly can lead to serious problems, such as seizures
    •Can raise your risk of suicidal thoughts or behavior
    •Commonly causes dizziness

  • Common Side Effects of Lyrica vs. Neurontin

    Common Side Effects for
    •Dizziness (8-29%)
    •Drowsiness (4-16%)
    •Swelling of hands, feet, arms, or legs (4-12%)
    •Dry mouth (2-7%)
    •Weight gain (4-6%)
    Common Side Effects for
    •Dizziness (17-28%)
    •Sleepiness (19-21%)
    •Poor muscle control/clumsiness (3-13%)
    •Fatigue (3-11%)

  • Warnings of Lyrica vs. Neurontin

    Common Side Effects for
    •Allergic reactions and severe swelling
    •Suicidal thoughts and behavior
    •Difficulty driving and concentrating
    •Breathing problems
    •Swelling in the limbs and weight gain
    •Withdrawal symptoms and risk of seizures
    •Possible risk of bleeds (from low platelet levels)
    •Possible risk of muscle breakdown
    Common Side Effects for
    •Severe allergic and skin reactions
    •Difficulty concentrating, extreme sleepiness, and dizziness
    •Withdrawal problems
    •Suicidal thoughts or behavior
    •Dangerously slow breathing (respiratory depression)
    •Brain and mental health side effects in children

  • Prices with our coupons for Lyrica vs. Neurontin

    Learn more about Pregabalin
    Learn more about Gabapentin

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