Compare Lyrica vs. Wellbutrin XL

Lyrica (Pregabalin) and bupropion (Wellbutrin XL, Wellbutrin SR) are both prescription medications, but they serve different purposes and belong to different drug classes. Lyrica is an antiepileptic used to treat nerve pain, fibromyalgia, and partial-onset seizures, while bupropion is an atypical antidepressant used to treat depression and seasonal affective disorder (SAD). Lyrica is taken 2 or 3 times a day and can cause dizziness and drowsiness, whereas bupropion is available in short-acting and long-acting forms, with the long-acting versions taken once daily. Bupropion is less likely to cause weight gain and sexual side effects compared to other antidepressants, but it can increase the risk of seizures, especially in people with a history of seizures or eating disorders. Lyrica, on the other hand, can cause weight gain and swelling in the limbs. Both medications require careful monitoring for side effects, but they address different health issues and have distinct risk profiles.