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Pregabalin Coupon - Pregabalin 75mg capsule

pregabalin

Generic Lyrica
Used for Epilepsy, Postherpetic Neuralgia, Diabetic Neuropathy, Fibromyalgia
Used for Epilepsy, Postherpetic Neuralgia, Diabetic Neuropathy, Fibromyalgia

Pregabalin (Lyrica) treats pain caused by nerve damage and fibromyalgia in adults. It can be used with other medications to prevent seizures for both adults and children. Pregabalin (Lyrica) is taken by mouth, typically 2 or 3 times a day. It's available as a capsule and oral solution. Some of the more common side effects of this medication include dizziness and drowsiness.

Last reviewed on March 22, 2023
Pregabalin (Lyrica) is a controlled substance, which means that it's more likely to be misused or cause dependence. There are federal and state laws that limit the amount of medication that can be prescribed or dispensed within a certain period of time.
basics-icon

What is Pregabalin (Lyrica)?

What is Pregabalin (Lyrica) used for?

How Pregabalin (Lyrica) works

Pregabalin (Lyrica) is an anticonvulsant. While the exact way it works to treat nerve pain and seizures isn't well-understood, it's thought to lower certain chemicals in the brain to relieve pain and prevent seizures.

Are you looking for information on extended-release form of pregabalin ER (Lyrica CR) instead?
When does Pregabalin (Lyrica) start working?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Initial effect
Full effect

Drug Facts

Common BrandsLyrica
Drug ClassAntiepileptic
Controlled Substance ClassificationSchedule V
Generic StatusLower-cost generic available
AvailabilityPrescription only

More on Pregabalin (Lyrica) essentials

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$342.740
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What are the risks and warnings for Pregabalin (Lyrica)?

Pregabalin (Lyrica) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

risk-warning

Allergic reactions and severe swelling

  • Risk factors: History of unusual swelling | Taking other medications that can cause swelling

    Although rare, angioedema (swelling of the face, tongue, neck, and/or other organs) can happen at any time when taking pregabalin (Lyrica). Sometimes, these reactions can be life-threatening because they affect your breathing. If you do experience a reaction, your provider will most likely ask you to stop taking pregabalin (Lyrica) and try different medication instead. Get medical help right away if you develop any head or neck swelling, hives, red skin, blisters, or trouble breathing.

    risk-warning

    Suicidal thoughts and behavior

    • Risk factors: Taking anti-seizure medications | History of depression

      Like other anti-seizure medications, pregabalin (Lyrica) can
      raise the risk of suicidal thoughts or behavior. This is rare, but can happen as early as 1 week after starting the medication. Tell your provider about new or worsening symptoms of depression or unusual changes in mood or behavior right away.

      risk-warning

      Difficulty driving and concentrating

      • Risk factors: Drinking alcohol | Taking other medications that cause drowsiness

        Taking pregabalin (Lyrica) can make you feel sleepy and affect your concentration and focus. These side effects tend to be higher when starting the medication or when taking higher doses. Avoid activities that require you to be alert, like driving or operating machinery, until you know how the medication affects you.

        risk-warning

        Breathing problems

        • Risk factors: History of breathing problems | Taking pregabalin (Lyrica) with CNS depressants

          It's best to avoid taking pregabalin (Lyrica) with other medications that can slow your breathing, such as opioid pain medications. Taking them together can lead to life-threatening breathing problems. If you're taking another medication that can slow breathing, your provider might prescribe you a lower dose of pregabalin (Lyrica). If you experience difficulty breathing, get medical help right away.

          risk-warning

          Swelling in the limbs and weight gain

          • Risk factors: Taking pregabalin (Lyrica) with certain diabetes medications

            Pregabalin (Lyrica) can cause swelling of the limbs, especially if you take certain diabetes medications, such as pioglitazone (Actos). Tell your provider if you have a history of heart problems before starting this medication since extra fluid can make conditions like heart failure worse. If you have a lot of swelling, contact your provider.

            Additionally, pregabalin (Lyrica) can commonly cause weight gain. Sometimes, the weight gain is related to the swelling from extra fluids, but this isn't the case for everyone. Your risk of weight gain is higher if you're taking a higher dose of pregabalin (Lyrica) for a longer period of time. Talk to your provider about ways to keep your weight healthy.

            risk-warning

            Withdrawal symptoms and risk of seizures

            • Risk factors: Stopping pregabalin (Lyrica) suddenly

              Don't suddenly stop taking pregabalin (Lyrica) without first talking with your provider. Doing so can lead to symptoms like nausea, headache, trouble sleeping, sweating, and diarrhea. In addition, if you've been taking pregabalin (Lyrica) to control seizures, stopping it suddenly can cause more seizures. If you want to stop taking this medication, let your provider know. They'll help you lower your dose slowly (over at least one week) before stopping completely.

              risk-warning

              Possible risk of bleeds (from low platelet levels)

              In clinical studies, some people taking pregabalin (Lyrica) had a lower amount of platelets (cells in your blood that help your blood clot). Typically, people who have low platelet levels are at a higher risk for bleeds. But data from clinical trials show that wasn't a higher number of bleeding events from taking pregabalin (Lyrica). To be safe, if you notice blood in your urine or stool, easy bruising, or bleeding that takes longer to stop, let your provider know. They can check your platelet count with a blood test to make sure it's within a safe range.

              risk-warning

              Possible risk of muscle breakdown

              Though rare, pregabalin (Lyrica) might raise your risk for a condition called rhabdomyolysis, which is when your muscles break down. Contact your provider if you notice unexplained muscle pain, tenderness, or weakness.

              basics-icon

              What are the side effects of Pregabalin (Lyrica)?

              The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

              Common Side Effects

              • Dizziness (8-29%)
              • Drowsiness (4-16%)
              • Swelling of hands, feet, arms, or legs (4-12%)
              • Dry mouth (2-7%)
              • Weight gain (4-6%)

              Other Side Effects

              • Weakness
              • Constipation
              • Accidental injury
              • Poor coordination or movement
              • Blurry or abnormal vision
              • Difficulty paying attention or concentrating

              Serious Side Effects

              Contact your healthcare provider immediately if you experience any of the following.
              • Angioedema: swelling in the face, lips, tongue, throat, hands, or feet, trouble breathing
              • Severe allergic reaction: hives, trouble breathing, swelling of the face, lips, tongue, or throat
              • Suicidal thoughts or behaviors
              • Severe drowsiness
              • Breathing problems
              When do Pregabalin (Lyrica) possible side effects begin and end?
              Time passed since treatment started:
              HOURS
              DAYS
              WEEKS
              MONTHS
              Dizziness
              Drowsiness
              If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

              Source: DailyMed

              The following side effects have also been reported

              Side effects that you should report to your care team as soon as possible:

              • Allergic reactions or angioedema—skin rash, itching, hives, swelling of the face, eyes, lips, tongue, arms, or legs, trouble swallowing or breathing
              • Blurry vision
              • Thoughts of suicide or self-harm, worsening mood, feelings of depression
              • Trouble breathing

              Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

              pros-and-cons

              Pros and cons of Pregabalin (Lyrica)

              thumbs-up

              Pros

              Works well to relieve nerve pain caused by diabetes, shingles, and spinal cord injuries

              Available in a capsule and oral solution

              Used in combination with other anti-seizure drugs to treat partial-onset seizures

              Available as a lower-cost generic

              thumbs-down

              Cons

              Can cause dizziness and drowsiness

              Must avoid drinking alcohol

              Not recommended for breastfeeding females

              Can cause weight gain

              pharmacist-tips

              Pharmacist tips for Pregabalin (Lyrica)

              pharmacist
              • You can take pregabalin (Lyrica) with or without food. Food won't affect how well this medication works for you.

                • If you're taking pregabalin (Lyrica) oral solution, make sure to use the measuring device provided to you at the pharmacy. Don't use household spoons because this could cause you to take or give the wrong amount of medication.

                  • Pregabalin (Lyrica) can cause dizziness, drowsiness, and blurry vision, so don't drive or do anything that requires concentration until you know how this medication affects you.

                    • Mixing pregabalin (Lyrica) with alcohol or other sedating medications (e.g., opioids, benzodiazepines, muscle relaxants) can make you very drowsy, affect your ability to react quickly, and slow your breathing. Tell your provider and pharmacist about all of your medications so they can check for potentially dangerous interactions.

                      • Talk to your healthcare provider if you want to stop taking pregabalin (Lyrica), especially if you're using it to prevent seizures. You'll need to lower your dose slowly over time to avoid any unwanted side effects, such as nausea, headache, trouble sleeping, and seizures.

                        • Pregabalin (Lyrica) can cause vision changes. Make sure to see your eye provider for your annual eye exam, and tell your provider if you notice any changes in your vision.

                          More on Pregabalin (Lyrica) tips

                          faqs

                          Frequently asked questions about Pregabalin (Lyrica)

                          How well does pregabalin (Lyrica) work for nerve pain?
                          While everyone will respond differently, studies have shown that roughly half of the people taking pregabalin (Lyrica) for various types of nerve pain saw their pain ease by about 30%. This is greater pain relief than what people experienced with placebo. In addition, when people first start pregabalin (Lyrica), some people noticed their pain improving in as early as one week. But it took longer for others to experience the benefit of this medication. Talk with your provider if you've more questions about how well this medications work to treat nerve pain.
                          What should I do if I miss a dose of pregabalin (Lyrica)?
                          If you forget to take your dose, take it as soon as you remember. If it's almost time for the next dose, just skip the missed dose. Never double up on pregabalin (Lyrica) to make up for a missed dose, because this can lead to dangerous side effects, such as drowsiness or trouble breathing.
                          Is pregabalin (Lyrica) safe during pregnancy?
                          There aren't enough studies to say whether taking pregabalin (Lyrica) during pregnancy is safe for your baby. In animal studies, it caused harm to babies born to mothers who took the medication during pregnancy. Some problems included bone abnormalities and low body weight. There's a North American Antiepileptic Drug (NAAED) Pregnancy Registry to monitor the safety of anti-seizure medications during pregnancy. If you're currently pregnant and taking pregabalin (Lyrica), it's encouraged that you enroll in the registry to help researchers learn more about the risks.
                          Why is pregabalin (Lyrica) a controlled substance?
                          Pregabalin (Lyrica) is classified as a schedule V controlled substance because during clinical studies it was found to have potential for addiction and dependence. This means the medication is more strictly regulated, and your pharmacy might have certain policies in place to help lower your risk for these issues.
                          Does pregabalin (Lyrica) help with sleep?
                          No, pregabalin (Lyrica) isn't FDA-approved to help with sleep. It's only approved to treat certain types of nerve-related pain and to prevent seizures. People who take pregabalin (Lyrica) can experience drowsiness as a side effect. In fact, pregabalin (Lyrica) can not only make you feel sleepy, but also make it difficult for you to concentrate or focus. Don't take pregabalin (Lyrica) with alcohol or other medications that can cause drowsiness, such as diphenhydramine (Benadryl), because doing so can raise your risk for falls or injuries. While there are some studies that looked at the use of pregabalin (Lyrica) for sleep, more research is needed in this area. Ask your provider if you've any questions about pregabalin (Lyrica) and sleep.
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                          dosage

                          Pregabalin (Lyrica) dosage forms

                          The average cost for 60 capsules of 75mg of Pregabalin (Lyrica) is $604.87 with a free GoodRx coupon. This is 21.66% off the average retail price of $772.16.
                          bottle of oral solution
                          Bottle of oral solution
                          DosageQuantityPrice as low asPrice per unit
                          473ml of 20mg/ml1 bottle$1202.35$1202.35
                          capsule
                          Capsule
                          DosageQuantityPrice as low asPrice per unit
                          25mg60 capsules$604.87$10.08
                          50mg60 capsules$604.87$10.08
                          75mg60 capsules$604.87$10.08
                          100mg60 capsules$604.87$10.08
                          150mg60 capsules$604.87$10.08
                          200mg60 capsules$588.07$9.80
                          225mg60 capsules$604.87$10.08
                          300mg60 capsules$592.64$9.88

                          Typical dosing for Pregabalin (Lyrica)

                          The dose will depend on why you're taking pregabalin (Lyrica). You'll typically start at a lower dose, and after 1 week your provider might raise your dose if needed.

                          Adults

                          • Nerve pain from diabetes: The typical starting dose is 50 mg by mouth 3 times a day.

                          • Nerve pain from shingles: The typical starting dose is 50 mg by mouth 3 times a day or 75 mg by mouth 2 times a day.

                          • Nerve pain from spinal cord injury or fibromyalgia: The typical starting dose is 75 mg by mouth 2 times a day.

                          • Partial-onset seizures (ages 17 years and older): The typical starting dose is 150 mg by mouth, split into 2 or 3 doses and taken throughout the day.

                          Children (ages 1 month and older)

                          • Partial-onset seizures (brand name Lyrica only): Your child's provider will calculate the dose based on your child's body weight. The typical starting dose ranges from 2.5 mg/kg to 3.5 mg/kg by mouth daily, split into 2 or 3 doses and throughout the day.

                          Your dose might differ if you have kidney problems.

                          More on Pregabalin (Lyrica) dosage forms

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                          What are alternatives to Pregabalin (Lyrica)?

                          There are a number of medications that your doctor can prescribe in place of Pregabalin (Lyrica). Compare a few possible alternatives below.
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                          Pregabalin (Lyrica) images

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                          References

                          Best studies we found

                          Alembic Pharmaceuticals Limited. (2023). PREGABALIN capsule [package insert]. DailyMed.

                          Boomershine, C.S. (2010). Pregabalin for the management of fibromyalgia syndrome. Journal of Pain Research.

                          Cho, Y. W., et al. (2014). Effects of Pregabalin in Patients with Hypnotic-Dependent Insomnia. Journal of Clinical Sleep Medicine.

                          View All References (4)

                          Derry, S., et al. (2019). Pregabalin for neuropathic pain in adults. The Cochrane Database of Systematic Reviews.

                          Kiriakopoulos, E. (n.d.). Focal onset aware seizures (simple partial seizures). Epilepsy Foundation.

                          Lyrica. (n.d.). Frequently asked questions about Lyrica.

                          Parke-Davis Div of Pfizer Inc. (2020). LYRICA- pregabalin capsule LYRICA- pregabalin solution [package insert]. DailyMed.

                          GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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