What is Fatigue?

Fatigue is characterized by low energy, tiredness, and low strength. Fatigue can be caused by disease, little physical activity, and mental conditions such as depression.

Treatment for fatigue includes resting, relaxing, eating healthy, exercising, therapy, and taking medications. Sympathomimetic-like agents and acetylcholine releasing agents are commonly prescribed to treat fatigue. They promote alertness and wakefulness.

Savings Tips for Fatigue

  • Provigil vs Nuvigil: Which Is Better for Daytime Sleepiness?

    September 09, 2015

    If you work the night shift and struggle to stay awake, or if you have daytime sleepiness from sleep apnea or other sleep disorders, you may have wondered if a medication can help you feel more alert.
    For excessive daytime sleepiness, Provigil and Nuvigil are first-line treatments. Provigil (the generic is modafinil) and Nuvigil are non-stimulant medications—but what does that mean? How do they work? And is one better than the other?
    How do Provigil and Nuvigil help keep you awake if they aren’t stimulants?

    • Most likely, Provigil (modafinil) and Nuvigil enhance dopamine signaling (meaning they make your body more sensitive to dopamine, a neurotransmitter than can promote wakefulness).
    •  See More
  • Is Your Medication Making You Tired?

    June 10, 2014

    One in ten visits to a primary care doctor is for fatigue. While certainly not the only cause, your medications can be the culprit for making you sleepy. Here are the players you need to know about.

    Beta blockers. These are medications used for high blood pressure, migraine prevention, control of heart rate in atrial fibrillation, and they improve mortality after heart attack. Ok, now for the downside. They can make you sleepy. See More

  • Wake Up! Provigil and Nuvigil, Relief from Fatigue

    July 19, 2013

    Folks with fatigue from obstructive sleep apnea or neurologic illnesses like multiple sclerosis see improvement in fatigue with Provigil and Nuvigil, but at a cost. Fatigue is a common complaint and a remedy may be worth paying money for.

    Modafinil (Provigil) acts on the central nervous system, although the mechanism for its effect is unknown. It is used as therapy for the treatment of excessive daytime sleepiness that persists in patients with obstructive sleep apnea (OSA) who have fatigue despite therapy (wearing the CPAP mask). See More

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Popular Fatigue Drugs

Popularity Drug Name Drug Class Price
Sympathomimetic-like Agents 103 See Prices
Sympathomimetic-like Agents 342 See Prices
see all 2 drugs

Note: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

Fatigue Drug Classes

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