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Tricyclic Antidepressants

Tricyclic antidepressants are used to treat depression, obsessive-compulsive disorder, insomnia, bed wetting, itching, and eczema. They work by increasing the amount of norepinephrine and serotonin in the brain to elevate mood, slow down brain activity, and relieve itching.

Why are tricyclic antidepressants prescribed?

  1. Depression (42%)
  2. Anxiety (19%)
  3. Alcohol Dependence (19%)
  4. Migraine (18%)
  5. Obsessive-Compulsive Disorder (2%)
  6. Bed Wetting (1%)
  7. Itching (0%)
  8. Eczema (0%)
  9. Insomnia (0%)

Key takeaways

Tricyclic antidepressants are used to treat depression. Some may treat other conditions, such as nerve pain, insomnia, and other mental health conditions. Tricyclic antidepressants work by balancing the levels of certain chemicals in your brain, such as serotonin and norepinephrine. Examples include amitriptyline, doxepin (Silenor), and nortriptyline (Pamelor).

Prices for popular Tricyclic Antidepressants medications
Viewing 12 of 12 medications
Amitriptyline is used to treat depression. It is more popular than comparable drugs. Amitriptyline is only available as a generic drug; all brands have been discontinued. Generic amitriptyline is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
DOXEPIN reduces itching caused by skin conditions, such as eczema. It works by blocking histamine, a substance released by the body during an allergic reaction.
Silenor (doxepin) is an expensive drug used to treat insomnia and helps you sleep through the night. It is slightly less popular than comparable drugs. There are currently no generic alternatives for Silenor. While 75% of insurance plans cover the most common version of Silenor at a co-pay of $32.50-$80.00, many of them have restrictions. Manufacturer and pharmacy coupons can help offset the cost.
DOXEPIN reduces itching caused by skin conditions, such as eczema. It works by blocking histamine, a substance released by the body during an allergic reaction.
Nortriptyline (Pamelor) is an inexpensive drug used to treat depression. It is slightly less popular than comparable drugs. It is available in generic and brand versions. Generic nortriptyline is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
DESIPRAMINE treats depression. It increases the amount of serotonin and norepinephrine in the brain, substances that help regulate mood. It belongs to a group of medications called tricyclic antidepressants (TCAs).
IMIPRAMINE treats depression. It increases the amount of serotonin and norepinephrine in the brain, substances that help regulate mood. It may also help reduce bedwetting in children. It belongs to a group of medications called tricyclic antidepressants (TCAs).
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amoxapine

as low as$18
AMOXAPINE treats depression. It increases the amount of serotonin and norepinephrine in the brain, substances that help regulate mood. It belongs to a group of medications called tricyclic antidepressants (TCAs).
CLOMIPRAMINE treats obsessive-compulsive disorder (OCD). It increases the amount of serotonin and norepinephrine in the brain, substances that help regulate mood. It belongs to a group of medications called tricyclic antidepressants (TCAs).
PROTRIPTYLINE treats depression. It increases the amount of serotonin and norepinephrine in the brain, substances that help regulate mood. It belongs to a group of medications called tricyclic antidepressants (TCAs).
TRIMIPRAMINE treats depression. It increases the amount of serotonin and norepinephrine in the brain, substances that help regulate mood. It belongs to a group of medications called tricyclic antidepressants (TCAs).
IMIPRAMINE treats depression. It increases the amount of serotonin and norepinephrine in the brain, substances that help regulate mood. It belongs to a group of medications called tricyclic antidepressants (TCAs).
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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