Major depression is a health condition where you feel sad and hopeless, or uninterested in your daily activities. Depression can cause other symptoms, too, like fatigue, problems sleeping, and appetite changes.
Antidepressants like fluoxetine (Prozac), bupropion (Wellbutrin), or venlafaxine (Effexor) are great options for treating major depression. But it can often be hard to tell if they’re making a difference, especially since the changes are gradual. Also, antidepressants can take a month or longer before they really start to kick in. This can leave you wondering: Is my medication actually working?