Head-to-head comparisons of medication uses, side effects, warnings, and more.
Bupropion
Alprazolam (Xanax)
Bupropion
Alprazolam (Xanax)
Summary of Wellbutrin XL vs. Xanax
Summary for Atypical antidepressant
Prescription only
Bupropion is taken by mouth to treat depression and seasonal affective disorder (SAD). It's available as short-acting tablets that are taken two or three times a day, as well as long-acting versions that are taken once daily. Bupropion has fewer sexual side effects compared to other antidepressants, but it's not a good choice for people with a history of seizures, eating disorders, or drink alcohol regularly.