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Compare Qelbree vs. Wellbutrin XL

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Qelbree (viloxazine)
    Bupropion
  • Qelbree (viloxazine)
    Bupropion

  • Summary of Qelbree vs. Wellbutrin XL

    Summary for NRI
    Prescription only

    Qelbree (viloxazine) is a medication used to treat attention-deficit hyperactivity disorder (ADHD) in children and adults. It's not a controlled substance like a lot of other ADHD medications, so it doesn't have a risk of abuse or dependence. Qelbree (viloxazine) is taken by mouth daily. And it can take at least 1 week before you notice your ADHD symptoms improving.

    Summary for Atypical antidepressant
    Prescription only

    Bupropion is taken by mouth to treat depression and seasonal affective disorder (SAD). It's available as short-acting tablets that are taken two or three times a day, as well as long-acting versions that are taken once daily. Bupropion has fewer sexual side effects compared to other antidepressants, but it's not a good choice for people with a history of seizures, eating disorders, or drink alcohol regularly.

  • Indications of Qelbree vs. Wellbutrin XL

    Indications for
    •Attention-deficit hyperactivity disorder (ADHD) in adults and children age 6 years and older
    Indications for
    •Depression
    •Seasonal affective disorder (SAD) - only bupropion HCl extended-release (Wellbutrin XL)

  • Pros and Cons of Qelbree vs. Wellbutrin XL

    Pros and Const for NRI
    Pros
    •Not a controlled substance, so there isn't a risk of abuse or dependence
    •Can take with or without food
    •Can sprinkle capsule contents over applesauce for people who have trouble swallowing capsules
    •Works well in children and adults
    Cons
    •Can take a week or longer before you notice your ADHD symptoms getting better
    •Can raise the risk of suicidal thoughts and behaviors, especially when first starting the medication
    •Interacts with a lot of medications such as duloxetine (Cymbalta) and tizanidine (Zanaflex)
    Pros and Const for Atypical antidepressant
    Pros
    •Works well for depression and can be used alone or in combination with other antidepressants
    •Causes fewer sexual side effects than some other antidepressants
    •Available in a lower-cost generic form
    •Less likely to cause weight gain compared to other antidepressants
    •Good option for people who haven't had success with traditional antidepressants like selective serotonin reuptake inhibitors (SSRIs)
    Cons
    •Can take several weeks to feel the full effects
    •Not the best option if you have a history of seizures or eating disorders like as anorexia or bulimia
    •Might need to limit or avoid using alcohol during treatment
    •Can cause trouble sleeping if you take it later in the day

  • Common Side Effects of Qelbree vs. Wellbutrin XL

    Common Side Effects for

    Adults

    •Trouble sleeping (23%)
    •Headache (17%)
    •Nausea (12%)
    •Extreme tiredness (12%)
    •Dry mouth (10%)
    •Not feeling hungry (10%)

    Children

    •Sleepiness (16%)
    •Headache (11%)
    •Not feeling hungry (7%)
    •Sore throat, cough, and other symptoms of an upper respiratory tract infection (7%)
    •Tiredness (6%)
    Common Side Effects for
    •Headache
    •Dry mouth
    •Nausea
    •Trouble sleeping
    •Dizziness
    •Sore throat
    •Constipation
    •Restlessness (agitation)

  • Warnings of Qelbree vs. Wellbutrin XL

    Common Side Effects for
    •Suicidal thoughts and unusual behavior
    •High blood pressure and fast heart rate
    •Not for use in bipolar disorder
    •Sleepiness
    •Drug interactions
    Common Side Effects for
    •Suicidal thoughts or behavior and abnormal mood changes
    •Mental health changes
    •Seizures
    •High blood pressure
    •Extreme enthusiasm or excitement (mania)

  • Prices with our coupons for Qelbree vs. Wellbutrin XL

    Learn more about Qelbree
    Learn more about Bupropion

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