Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Amphetamine sulfate (brands like Evekeo and Adzenys XR ODT) and Adderall (dextroamphetamine/amphetamine salts) are both stimulant medications used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. However, there are some key differences between them. Amphetamine sulfate contains only one type of amphetamine, while Adderall is a mix of different amphetamine salts, including amphetamine sulfate. This mixture in Adderall can sometimes make it more effective for some people. Amphetamine sulfate is also approved for short-term treatment of obesity, while Adderall is not. Both medications can cause side effects like trouble sleeping and loss of appetite, but they need to be taken exactly as prescribed to avoid misuse and dependence. Adderall is available as a lower-cost generic, while some forms of amphetamine sulfate are only available as brand-name medications. Both medications should be used with caution, especially if you have a history of heart problems or mental health issues.
Amphetamine (Evekeo)
Adderall
Amphetamine (Evekeo)
Adderall
Summary of Evekeo vs. Adderall
Summary for Stimulant
Prescription only
Immediate-release amphetamine, also known under the brand name Evekeo, is a stimulant. It's used to treat attention deficit-hyperactivity disorder (ADHD) in people 3 years and older. This medication can also help adults and some kids with narcolepsy. It's also approved to be used for a few weeks as an add-on treatment for obesity in people 12 and older. Immediate-release amphetamine comes as a tablet that you swallow with liquid. The dosage depends on why you're taking it and how well it works for you. Side effects can include loss of appetite and trouble sleeping. There are brand-name and generic versions. But there are special restrictions to get it because it's a controlled substance.
Summary for Stimulant
Prescription only
Adderall is a stimulant medication that's used to treat attention deficit-hyperactivity disorder (ADHD) and narcolepsy in adults and children. It contains the instant-release (IR) forms of dextroamphetamine and amphetamine salts. Adderall is available as a brand-name and lower-cost generic tablet that's taken by mouth. Your psychiatrist will adjust the dosage for you based on how well the medication works for you. Common side effects include trouble sleeping and loss of appetite.