Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Evekeo vs. Concerta

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Amphetamine sulfate (Evekeo, Adzenys XR ODT) and Methylphenidate ER (Concerta, Ritalin LA) are both stimulants used to treat attention deficit hyperactivity disorder (ADHD), but they have some differences. Amphetamine sulfate is also approved for narcolepsy and short-term obesity treatment, while Methylphenidate ER is only approved for ADHD. Amphetamine sulfate comes in various forms, including tablets, dissolvable tablets, and liquids, whereas Methylphenidate ER is available in tablets, capsules, chewable tablets, and liquids. Both medications can cause side effects like trouble sleeping and loss of appetite, but Methylphenidate ER can also cause headaches and stomach pain. Amphetamine sulfate works by increasing norepinephrine, dopamine, and serotonin levels, while Methylphenidate ER mainly affects norepinephrine and dopamine. Both medications have a risk of misuse and dependence and are controlled substances. If you're pregnant or breastfeeding, it's important to discuss the risks and benefits of these medications with your provider.

  • Amphetamine (Evekeo)
    Methylphenidate er
  • Amphetamine (Evekeo)
    Methylphenidate er

  • Summary of Evekeo vs. Concerta

    Summary for Stimulant
    Prescription only

    Immediate-release amphetamine, also known under the brand name Evekeo, is a stimulant. It's used to treat attention deficit-hyperactivity disorder (ADHD) in people 3 years and older. This medication can also help adults and some kids with narcolepsy. It's also approved to be used for a few weeks as an add-on treatment for obesity in people 12 and older. Immediate-release amphetamine comes as a tablet that you swallow with liquid. The dosage depends on why you're taking it and how well it works for you. Side effects can include loss of appetite and trouble sleeping. There are brand-name and generic versions. But there are special restrictions to get it because it's a controlled substance.

    Summary for Stimulant
    Prescription only

    Methylphenidate extended-release (ER) is a first-choice option for people with attention deficit-hyperactivity disorder (ADHD). This once-daily medication can start to work within 2 hours and can last throughout the day. Methylphenidate ER can cause difficulty sleeping and a loss of appetite. It also has a potential risk of misuse and dependency and is thus a controlled substance.

  • Indications of Evekeo vs. Concerta

    Indications for
    •Attention deficit-hyperactivity disorder (ADHD)
    •Narcolepsy
    •Short-term add-on treatment for obesity
    Indications for
    •Attention-deficit/hyperactivity disorder (ADHD)

  • Pros and Cons of Evekeo vs. Concerta

    Pros and Const for Stimulant
    Pros
    •One of the first-choice medications for ADHD
    •Typically works within 45 minutes
    Cons
    •Has a risk of misuse and dependence
    •Lasts just 4 to 6 hours, so might need to take more than one time each day
    •Can cause higher blood pressure
    Pros and Const for Stimulant
    Pros
    •First-choice medication for ADHD
    •Taken only once per day
    •Available in many different forms (e.g., pills, chewable tablet, liquid)
    •Some brands available in lower-cost generic form
    •Can be prescribed for children as young as 6 years old
    Cons
    •Has a risk of misuse and dependency
    •A controlled medication, so there are special requirements for getting the prescription filled
    •Dose needs to be raised and lowered slowly to avoid bothersome side effects like distress and trouble sleeping
    •Not the best choice for pregnant or breastfeeding females or people with heart conditions
    •Can interact with certain blood pressure medications and depression medications

  • Common Side Effects of Evekeo vs. Concerta

    Common Side Effects for
    •Low appetite
    •Trouble sleeping
    •Headache
    Common Side Effects for

    Side effects might differ depending on the formulation and brand. In general:

    •Headache
    •Low appetite
    •Stomach pain
    •Trouble sleeping

  • Warnings of Evekeo vs. Concerta

    Common Side Effects for
    •Risk of misuse and addiction
    •Risks to people with serious heart conditions
    •Higher blood pressure and faster heart rate
    •Strange thoughts or behaviors
    •Slow growth in children
    •Seizures
    •Problems with blood flow in the arms and legs, including Raynaud's phenomenon
    •Serotonin syndrome
    Common Side Effects for
    •Misuse and dependence
    •Serious heart problems
    •Changes in behavior or thoughts
    •Prolonged and painful erection
    •Blood circulation problem (Raynaud's phenomenon)
    •Slowed growth in children
    •Serotonin syndrome
    •Drug interactions

  • Prices with our coupons for Evekeo vs. Concerta

    Learn more about Amphetamine
    Learn more about Methylphenidate er

Compare other ADHD drugs

Evekeo vs AdderallEvekeo vs ConcertaEvekeo vs FocalinEvekeo vs MydayisEvekeo vs RitalinEvekeo vs VyvanseAdderall vs ConcertaAdderall vs StratteraAdderall vs XanaxAdderall Xr vs AdderallArmodafinil vs AdderallAtivan vs AdderallAzstarys vs AdderallDaytrana vs AdderallDesoxyn vs AdderallDexedrine vs AdderallDextroamphetamine vs AdderallFocalin vs AdderallGuanfacine vs AdderallIntuniv vs AdderallKapvay vs AdderallLexapro vs AdderallModafinil vs AdderallMydayis vs AdderallNamenda vs AdderallPhentermine vs AdderallProzac vs AdderallQelbree vs AdderallRitalin vs AdderallSunosi vs Adderall
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.