Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Amphetamine (Evekeo, Evekeo ODT, Adzenys XR ODT, Dyanavel XR) and Vyvanse (lisdexamfetamine) are both stimulant medications used to treat attention deficit-hyperactivity disorder (ADHD). They work by increasing levels of certain chemicals in the brain, such as norepinephrine, dopamine, and serotonin. However, they differ in several ways. Amphetamine is available in various forms, including immediate-release and extended-release tablets, orally disintegrating tablets, and oral liquids, while Vyvanse is available as capsules and chewable tablets. Amphetamine is also approved for narcolepsy and short-term obesity treatment, whereas Vyvanse is approved for moderate-to-severe binge eating disorder (BED) in adults. Vyvanse is typically taken once daily, while amphetamine dosing can vary based on the form and condition being treated. Both medications have a risk of misuse and dependence, potential to cause serious heart problems, and changes in behavior or thoughts. Common side effects for both include difficulty sleeping, loss of appetite, dry mouth and stomach pain. It's important to take these medications exactly as prescribed and discuss any concerns with your healthcare provider.
Amphetamine (Evekeo)
Vyvanse (lisdexamfetamine)
Amphetamine (Evekeo)
Vyvanse (lisdexamfetamine)
Summary of Evekeo vs. Vyvanse
Summary for Stimulant
Prescription only
Immediate-release amphetamine, also known under the brand name Evekeo, is a stimulant. It's used to treat attention deficit-hyperactivity disorder (ADHD) in people 3 years and older. This medication can also help adults and some kids with narcolepsy. It's also approved to be used for a few weeks as an add-on treatment for obesity in people 12 and older. Immediate-release amphetamine comes as a tablet that you swallow with liquid. The dosage depends on why you're taking it and how well it works for you. Side effects can include loss of appetite and trouble sleeping. There are brand-name and generic versions. But there are special restrictions to get it because it's a controlled substance.
Summary for Stimulant
Prescription only
Vyvanse, the brand name for lisdexamfetamine, is a stimulant medication. It's used to treat attention deficit-hyperactivity disorder (ADHD) in people 6 years and older. It can also treat binge eating disorder (BED) in adults. Vyvanse (lisdexamfetamine) comes as capsules and chewable tablets. It's taken once per day in the morning. The dosage starts low and gets adjusted based on how you respond to the medication. Common side effects include trouble sleeping and loss of appetite. Vyvanse (lisdexamfetamine) is a controlled substance because it has a high risk of misuse and dependency.